Search Results - "Jansen, Pernille"

Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator of Hepatic Lipoprotein Export by Kjolby, Mads, Andersen, Olav M., Breiderhoff, Tilman, Fjorback, Anja W., Pedersen, Karen Marie, Madsen, Peder, Jansen, Pernille, Heeren, Joerg, Willnow, Thomas E., Nykjaer, Anders

“…Recent genome-wide association studies (GWAS) have revealed strong association of hypercholesterolemia and myocardial infarction with SNPs on human chromosome…”
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Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury by Willnow, Thomas E, Nykjaer, Anders, Jansen, Pernille, Giehl, Klaus, Nyengaard, Jens R, Teng, Kenneth, Lioubinski, Oleg, Sjoegaard, Susanne S, Breiderhoff, Tilman, Gotthardt, Michael, Lin, Fuyu, Eilers, Andreas, Petersen, Claus M, Lewin, Gary R, Hempstead, Barbara L

“…Neurotrophins are essential for development and maintenance of the vertebrate nervous system. Paradoxically, although mature neurotrophins promote neuronal…”
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Neuronal Sorting Protein-Related Receptor sorLA/LR11 Regulates Processing of the Amyloid Precursor Protein by Andersen, Olav M., Reiche, Juliane, Schmidt, Vanessa, Gotthardt, Michael, Spoelgen, Robert, Behlke, Joachim, Christine A. F. von Arnim, Breiderhoff, Tilman, Jansen, Pernille, Wu, Xin, Bales, Kelly R., Cappai, Roberto, Masters, Colin L., Gliemann, Jørgen, Mufson, Elliott J., Hyman, Bradley T., Paul, Steven M., Nykjær, Anders, Willnow, Thomas E., Ingram, Vernon Martin

“…sorLA (sorting protein-related receptor) is a type-1 membrane protein of unknown function that is expressed in neurons. Its homology to sorting receptors that…”
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Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling by Vaegter, Christian B, Nykjaer, Anders, Jansen, Pernille, Fjorback, Anja W, Glerup, Simon, Skeldal, Sune, Kjolby, Mads, Richner, Mette, Erdmann, Bettina, Nyengaard, Jens R, Tessarollo, Lino, Lewin, Gary R, Willnow, Thomas E, Chao, Moses V

“…The receptor sortilin has been implicated in pro-apoptotic signaling of proneurotrophins. In this study, the authors uncover another role for sortilin in…”
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Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons by Tauris, Jacob, Gustafsen, Camilla, Christensen, Erik Ilsø, Jansen, Pernille, Nykjaer, Anders, Nyengaard, Jens R., Teng, Kenneth K., Schwarz, Elisabeth, Ovesen, Therese, Madsen, Peder, Petersen, Claus Munck

“…The precursor of the neurotrophin (NT) nerve growth factor (NGF) (proNGF) serves physiological functions distinct from its mature counterpart as it induces…”
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Sortilin is essential for proNGF-induced neuronal cell death by Nykjaer, Anders, Lee, Ramee, Teng, Kenneth K, Jansen, Pernille, Madsen, Peder, Nielsen, Morten S, Jacobsen, Christian, Kliemannel, Marco, Schwarz, Elisabeth, Willnow, Thomas E, Hempstead, Barbara L, Petersen, Claus M

“…Sortilin (∼95 kDa) is a member of the recently discovered family of Vps10p-domain receptors, and is expressed in a variety of tissues, notably brain, spinal…”
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Hypocalcemia and osteopathy in mice with kidney‐specific megalin gene defect by Leheste, Jörg R., Melsen, Flemming, Wellner, Maren, Jansen, Pernille, Schlichting, Uwe, Renner‐Müller, Ingrid, Andreassen, Troels T., Wolf, Eckehard, Bachmann, Sebastian, Nykjaer, Anders, Willnow, Thomas E.

“…Megalin is an endocytic receptor highly expressed in the proximal tubules of the kidney. Recently, we demonstrated that this receptor is essential for the…”
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Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons: ProNT3 induces Sortilin-dependent death by Tauris, Jacob, Gustafsen, Camilla, Christensen, Erik Ilsø, Jansen, Pernille, Nykjaer, Anders, Nyengaard, Jens R., Teng, Kenneth K., Schwarz, Elisabeth, Ovesen, Therese, Madsen, Peder, Petersen, Claus Munck

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Erratum: Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling by Vaegter, Christian B, Jansen, Pernille, Fjorback, Anja W, Glerup, Simon, Skeldal, Sune, Kjolby, Mads, Richner, Mette, Erdmann, Bettina, Nyengaard, Jens R, Tessarollo, Lino, Lewin, Gary R, Willnow, Thomas E, Chao, Moses V, Nykjaer, Anders

“…Nat. Neurosci. 14, 54–61 (2011); published online 21 November 2010; corrected after print 14 January 2011 In the version of this article initially published,…”
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Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

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Sortilin associates with Trk receptors to enhance anterograde transport and signaling by neurotrophins by Vaegter, Christian Bjerggaard, Jansen, Pernille, Winther Fjorback, Anja, Glerup, Simon, Skeldal, Sune, Kjolby, Mads, Richner, Mette, Erdmann, Bettina, Nyengaard, Jens Randel, Tessarollo, Lino, Lewin, Gary R., Willnow, Thomas T E, Chao, Moses Victor, Nykjaer, Anders

“…Binding of target-derived neurotrophins to Trk receptors at nerve terminals are required to stimulate neuronal survival, differentiation, innervation and…”
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Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1‐methyl‐4‐phenylpyridinium in nigral slice cultures by Madsen, Jakob Torp, Jansen, Pernille, Hesslinger, Christian, Meyer, Morten, Zimmer, Jens, Gramsbergen, Jan Bert

“…Complex‐I inhibition and oxidative processes have been implicated in the loss of nigral dopamine neurones in Parkinson's disease and the toxicity of MPTP and…”
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Fetal antigen 1 (FA1) in the human pancreas: cell type expression, topological and quantitative variations during development by Tornehave, D, Jansen, P, Teisner, B, Rasmussen, H B, Chemnitz, J, Moscoso, G

“…Monospecific rabbit anti-human fetal antigen 1 (FA1), was used to examine the distribution of FA1 during the development of the human fetal pancreas and liver…”
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