Search Results - "Jansen, Hans J."
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Scaffolding pre-assembled contigs using SSPACE
Published in Bioinformatics (Oxford, England) (15-02-2011)“…De novo assembly tools play a main role in reconstructing genomes from next-generation sequencing (NGS) data and usually yield a number of contigs. Using…”
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RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection
Published in Frontiers in immunology (17-04-2019)“…Macrophages are phagocytic cells from the innate immune system, which forms the first line of host defense against invading pathogens. These highly dynamic…”
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Primitive duplicate Hox clusters in the European eel's genome
Published in PloS one (24-02-2012)“…The enigmatic life cycle and elongated body of the European eel (Anguilla anguilla L., 1758) have long motivated scientific enquiry. Recently, eel research has…”
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Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen
Published in Antimicrobial agents and chemotherapy (01-02-2015)“…The translational value of zebrafish high-throughput screens can be improved when more knowledge is available on uptake characteristics of potential drugs. We…”
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MinION Analysis and Reference Consortium: Phase 1 data release and analysis
Published in F1000 research (2015)“…The advent of a miniaturized DNA sequencing device with a high-throughput contextual sequencing capability embodies the next generation of large scale…”
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Genome and transcriptome analysis of the beet armyworm Spodoptera exigua reveals targets for pest control
Published in G3 : genes - genomes - genetics (19-10-2021)“…The genus Spodoptera (Lepidoptera: Noctuidae) includes some of the most infamous insect pests of cultivated plants including Spodoptera frugiperda, Spodoptera…”
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MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry [version 1; peer review: 1 approved, 2 approved with reservations]
Published in F1000 research (2017)“…Background: Long-read sequencing is rapidly evolving and reshaping the suite of opportunities for genomic analysis. For the MinION in particular, as both the…”
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Deep RNA sequencing of the skeletal muscle transcriptome in swimming fish
Published in PloS one (08-01-2013)“…Deep RNA sequencing (RNA-seq) was performed to provide an in-depth view of the transcriptome of red and white skeletal muscle of exercised and non-exercised…”
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The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids
Published in Communications biology (24-11-2023)“…Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized metabolites mainly produced in Gentianales to cope with environmental…”
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The Human Pathogen Mycobacterium tuberculosis and the Fish Pathogen Mycobacterium marinum Trigger a Core Set of Late Innate Immune Response Genes in Zebrafish Larvae
Published in Biology (Basel, Switzerland) (01-09-2024)“…Zebrafish is a natural host of various species and a surrogate model organism for tuberculosis research. is evolutionarily one of the closest non-tuberculous…”
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The Madagascar palm genome provides new insights on the evolution of Apocynaceae specialized metabolism
Published in Heliyon (30-03-2024)“…Specialized metabolites possess diverse interesting biological activities and some cardenolides- and monoterpene indole alkaloids- (MIAs) derived…”
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Corrigendum: RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection
Published in Frontiers in immunology (02-12-2019)“…[This corrects the article DOI: 10.3389/fimmu.2019.00832.]…”
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Changes in ovarian gene expression profiles and plasma hormone levels in maturing European eel ( Anguilla anguilla ); Biomarkers for broodstock selection
Published in General and comparative endocrinology (01-01-2016)“…Highlights • Wild female European eels provide leads for predictive maturation biomarkers. • Expression of steroidogenic genes is increased in…”
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An updated version of the Madagascar periwinkle genome [version 1; peer review: 2 approved]
Published in F1000 research (2022)“…The Madagascar periwinkle, Catharanthus roseus, belongs to the Apocynaceae family. This medicinal plant, endemic to Madagascar, produces many important drugs…”
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Comparison of the exomes of common carp (Cyprinus carpio) and zebrafish (Danio rerio)
Published in Zebrafish (01-06-2012)“…Research on common carp, Cyprinus carpio, is beneficial for zebrafish research because of resources available owing to its large body size, such as the…”
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De novo whole-genome assembly of a wild type yeast isolate using nanopore sequencing
Published in F1000 research (01-01-2017)“…Background : The introduction of the MinION sequencing device by Oxford Nanopore Technologies may greatly accelerate whole genome sequencing. Nanopore sequence…”
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Analyzing the function of a hox gene: An evolutionary approach
Published in Development, growth & differentiation (01-12-2011)“…We present an evolutionary approach to dissecting conserved developmental mechanisms. We reason that important mechanisms for making the bodyplan will act…”
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king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
Published in Proceedings of the National Academy of Sciences - PNAS (17-12-2013)“…Snakes are limbless predators, and many species use venom to help overpower relatively large, agile prey. Snake venoms are complex protein mixtures encoded by…”
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XMeis3 is necessary for mesodermal Hox gene expression and function
Published in PloS one (28-03-2011)“…Hox transcription factors provide positional information during patterning of the anteroposterior axis. Hox transcription factors can co-operatively bind with…”
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Rapid de novo assembly of the European eel genome from nanopore sequencing reads
Published in Scientific reports (03-08-2017)“…We have sequenced the genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically…”
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