Search Results - "Jansen, Felix"

Extracellular Vesicles in Cardiovascular Disease by Jansen, Felix, Nickenig Georg, Werner, Nikos

“…Extracellular vesicles originate from diverse subcellular compartments and are released in the extracellular space. By transferring their cargoes into target…”
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Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches by Düsing, Philip, Zietzer, Andreas, Goody, Philip Roger, Hosen, Mohammed Rabiul, Kurts, Christian, Nickenig, Georg, Jansen, Felix

“…Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney disease (CKD). Both conditions are rising in incidence as well as…”
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Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles by Jansen, Felix, Yang, Xiaoyan, Hoelscher, Marion, Cattelan, Arianna, Schmitz, Theresa, Proebsting, Sebastian, Wenzel, Daniela, Vosen, Sarah, Franklin, Bernardo S, Fleischmann, Bernd K, Nickenig, Georg, Werner, Nikos

“…BACKGROUND—Repair of the endothelium after vascular injury is crucial for preserving endothelial integrity and preventing the development of vascular disease…”
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Role and Function of MicroRNAs in Extracellular Vesicles in Cardiovascular Biology by Pfeifer, Philipp, Jansen, Felix, Werner, Nikos

“…Intercellular communication mediated by extracellular vesicles is crucial for preserving vascular integrity and in the development of cardiovascular disease…”
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Targeting microRNA-10 in glioma; a focus with potential therapeutic application in genome editing by Maus, Katharina, Jansen, Felix, Hosen, Mohammed Rabiul

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Endothelial- and Immune Cell-Derived Extracellular Vesicles in the Regulation of Cardiovascular Health and Disease by Jansen, Felix, MD, Li, Qian, MD, Pfeifer, Alexander, MD, PhD, Werner, Nikos, MD

“…Summary Intercellular signaling by extracellular vesicles (EVs) is a route of cell-cell crosstalk that allows cells to deliver biological messages to specific…”
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Effects of high intensity training and high volume training on endothelial microparticles and angiogenic growth factors by Wahl, Patrick, Jansen, Felix, Achtzehn, Silvia, Schmitz, Theresa, Bloch, Wilhelm, Mester, Joachim, Werner, Nikos

“…Endothelial microparticles (EMP) are complex vesicular structures shed from activated or apoptotic endothelial cells. As endurance exercise affects the…”
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Acute Effects of Different Exercise Protocols on the Circulating Vascular microRNAs -16, -21, and -126 in Trained Subjects by Wahl, Patrick, Wehmeier, Udo F, Jansen, Felix J, Kilian, Yvonne, Bloch, Wilhelm, Werner, Nikos, Mester, Joachim, Hilberg, Thomas

“…mircoRNAs (miRNAs), small non-coding RNAs regulating gene expression, are stably secreted into the blood and circulating miRNAs (c-miRNAs) may play an…”
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Endothelial microparticle-promoted inhibition of vascular remodeling is abrogated under hyperglycaemic conditions by Jansen, Felix, Zietzer, Andreas, Stumpf, Tobias, Flender, Anna, Schmitz, Theresa, Nickenig, Georg, Werner, Nikos

“…Endothelial microparticles (EMPs) inhibit vascular remodeling by transferring functional microRNA (miRNA) into target vascular smooth muscle cells (VSMCs)…”
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The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles by Zietzer, Andreas, Hosen, Mohammed Rabiul, Wang, Han, Goody, Philip Roger, Sylvester, Marc, Latz, Eicke, Nickenig, Georg, Werner, Nikos, Jansen, Felix

“…The transfer of microRNAs (miRs) via extracellular vesicles (EVs) is a functionally relevant mechanism of intercellular communication that regulates both organ…”
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Analysis of nocturnal, hypoxia-induced miRNAs in sleep apnea patients by Goody, Philip Roger, Nachtsheim, Lisa, Hosen, Mohammed Rabiul, von Krosigk, Miriam, Christmann, Dominik, Klussmann, Jens Peter, Zietzer, Andreas, Breitrück, Nils, Jansen, Felix, Jansen, Stefanie

“…Obstructive sleep apnea syndrome (OSAS) is associated with an increased cardiovascular risk. The underlying mechanisms are largely unclear. MicroRNAs (miRNAs)…”
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Sodium thiocyanate treatment attenuates atherosclerotic plaque formation and improves endothelial regeneration in mice by Zietzer, Andreas, Niepmann, Sven Thomas, Camara, Bakary, Lenart, Monika Anna, Jansen, Felix, Becher, Marc Ulrich, Andrié, René, Nickenig, Georg, Tiyerili, Vedat

“…Atherosclerotic plaque formation is an inflammatory process that involves the recruitment of neutrophil granulocytes and the generation of reactive oxygen…”
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Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease by Babelova, Andrea, Jansen, Felix, Sander, Kerstin, Löhn, Matthias, Schäfer, Liliana, Fork, Christian, Ruetten, Hartmut, Plettenburg, Oliver, Stark, Holger, Daniel, Christoph, Amann, Kerstin, Pavenstädt, Hermann, Jung, Oliver, Brandes, Ralf P

“…Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of…”
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Acute Coronary Syndrome as an Unusual Initial Presentation of T-Prolymphocytic Leukemia: A Case Report and Review of the Literature by Klein, Christian R, Jansen, Felix, Brossart, Peter, Herling, Marco, Feldmann, Georg

“…T-prolymphocytic leukaemia (T-PLL) is the most common mature T-cell leukaemia in Central Europe and is often manifested by rapidly increasing lymphocytosis,…”
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CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling by Hosen, Mohammed Rabiul, Li, Qian, Liu, Yangyang, Zietzer, Andreas, Maus, Katharina, Goody, Philip, Uchida, Shizuka, Latz, Eicke, Werner, Nikos, Nickenig, Georg, Jansen, Felix

“…Long noncoding RNAs (lncRNAs) have emerged as biomarkers and regulators of cardiovascular disease. However, the expression pattern of circulating extracellular…”
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Analysis of circulating ceramides and hexosylceramides in patients with coronary artery disease and type II diabetes mellitus by Düsing, Philip, Heinrich, Nadine N, Al-Kassou, Baravan, Gutbrod, Katharina, Dörmann, Peter, Nickenig, Georg, Jansen, Felix, Zietzer, Andreas

“…Abstract Background Cardiovascular disease (CVD) remains the leading cause of death worldwide. The main driving force behind this association is coronary…”
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Editorial: Comorbidities and Aortic Valve Stenosis: Molecular Mechanism, Risk Factors and Novel Therapeutic Options by St Hilaire, Cynthia, Jansen, Felix, Goettsch, Claudia

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Sustained apnea induces endothelial activation by Eichhorn, Lars, Dolscheid‐Pommerich, Ramona, Erdfelder, Felix, Ayub, Muhammad Ajmal, Schmitz, Theresa, Werner, Nikos, Jansen, Felix

“…Background Apnea diving has gained worldwide popularity, even though the pathophysiological consequences of this challenging sport on the human body are poorly…”
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Kinetics of Circulating MicroRNAs in Response to Cardiac Stress in Patients With Coronary Artery Disease by Jansen, Felix, Schäfer, Lisa, Wang, Han, Schmitz, Theresa, Flender, Anna, Schueler, Robert, Hammerstingl, Christoph, Nickenig, Georg, Sinning, Jan‐Malte, Werner, Nikos

“…Background Circulating microRNAs (miRNAs/miRs) are regulated in patients with coronary artery disease. The impact of transient coronary ischemia on circulating…”
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AIM2 Stimulation Impairs Reendothelialization and Promotes the Development of Atherosclerosis in Mice by Lüsebrink, Enzo, Goody, Philip Roger, Lahrmann, Catharina, Flender, Anna, Niepmann, Sven Thomas, Zietzer, Andreas, Schulz, Christian, Massberg, Steffen, Jansen, Felix, Nickenig, Georg, Zimmer, Sebastian, Krogmann, Alexander Otto

“…Background: Atherosclerosis has been shown to result from chronic inflammation caused by constitutive activation of the pattern recognition receptors (PRR),…”
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