Search Results - "Jansen, Angelique C M"

Dyslipidemia of Mothers With Familial Hypercholesterolemia Deteriorates Lipids in Adult Offspring by van der Graaf, Anouk, Vissers, Maud N, Gaudet, Daniel, Brisson, Diane, Sivapalaratnam, Suthesh, Roseboom, Tessa J, Jansen, Angelique C.M, Kastelein, John J.P, Hutten, Barbara A

“…OBJECTIVE—It is unknown whether elevated maternal low-density lipoprotein cholesterol (LDL-C) levels lead to dyslipidemia in the offspring. Because this could…”
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Relative risk for cardiovascular atherosclerotic events after smoking cessation: 6-9 years excess risk in individuals with familial hypercholesterolemia by Kramer, Anneke, Jansen, Angelique C M, van Aalst-Cohen, Emily S, Tanck, Michael W T, Kastelein, John J P, Zwinderman, Aeilko H

“…Smoking history is often di- or trichotomized into for example "never, ever or current smoking". However, smoking must be treated as a time-dependent covariate…”
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Diagnosing familial hypercholesterolaemia: the relevance of genetic testing by van Aalst-Cohen, Emily S, Jansen, Angelique C M, Tanck, Michael W T, Defesche, Joep C, Trip, Mieke D, Lansberg, Peter J, Stalenhoef, Anton F H, Kastelein, John J P

“…We assembled a cohort of patients with familial hypercholesterolaemia (FH) for both basic and clinical research. We used a set of established diagnostic…”
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Guidelines were developed for data collection from medical records for use in retrospective analyses by Jansen, Angelique C.M., van Aalst-Cohen, Emily S., Hutten, Barbara A., Büller, Harry R., Kastelein, John J.P., Prins, Martin H.

“…To construct a set of guidelines for data collection from medical records. Retrospective analysis of clinical data is often performed by physician-scientists…”
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Genetic Determinants of Cardiovascular Disease Risk in Familial Hypercholesterolemia by Jansen, Angelique C.M, van Aalst-Cohen, Emily S, Tanck, Michael W.T, Cheng, Suzanne, Fontecha, Marcel R, Li, Jia, Defesche, Joep C, Kastelein, John J.P

“…OBJECTIVE—To investigate the contribution of polymorphisms in multiple candidate genes to cardiovascular disease (CVD) risk in a large cohort of patients with…”
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Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia by VAN AALST-COHEN, Emily S, JANSEN, Angelique C. M, BOEKHOLDT, S. Matthijs, TANCK, Michael W. T, FONTECHA, Marcel R, CHENG, Suzanne, JIA LI, DEFESCHE, Joep C, KUIVENHOVEN, Jan Albert, KASTELEIN, John J. P

“…The objective of this study was to determine the extent to which common genetic variants can explain the variation of high-density lipoprotein cholesterol…”
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Phenotypic variability in familial hypercholesterolaemia: an update by Jansen, Angelique C M, van Wissen, Sanne, Defesche, Joep C, Kastelein, John J P

“…Heterozygous familial hypercholesterolaemia is among the most common inherited dominant disorders, and is characterized by severely elevated LDL-cholesterol…”
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Variation at the paraoxonase gene locus contributes to carotid arterial wall thickness in subjects with familial hypercholesterolemia by Roest, Mark, Jansen, Angelique C.M., Barendrecht, Arjan, Leus, Frank R., Kastelein, John J.P., Voorbij, Hieronymus A.M.

“…Paraoxonase (PON1) is a potent enzyme, physically associated with the high-density lipoprotein particle. PON1 may protect against cardiovascular disease (CVD),…”
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Diagnosing familial hypercholesterolaemia : the relevance of genetic testing. Commentary by DAMGAARD, Dorte, FAERGEMAN, Ole, VAN AALST-COHEN, Emily S, JANSEN, Angelique C. M, TANCK, Michael W. T, DEFESCHE, Joep C, TRIP, Mieke D, LANSBERG, Peter J, STALENHOEF, Anton F. H, KASTELEIN, John J. P

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Clinical, diagnostic, and therapeutic aspects of familial hypercholesterolemia by van Aalst-Cohen, Emily S, Jansen, Angelique C M, de Jongh, Saskia, de Sauvage Nolting, Pernette R W, Kastelein, John J P

“…Heterozygous familial hypercholesterolemia (FH) is a common inherited disorder of lipoprotein metabolism. FH is characterized by elevated levels of low-density…”
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