Search Results - "Janse, C.J."

Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites by Franke-Fayard, B., Djokovic, D., Dooren, M.W., Ramesar, J., Waters, A.P., Falade, M.O., Kranendonk, M., Martinelli, A., Cravo, P., Janse, C.J.

“…We report two improved assays for in vitro and in vivo screening of chemicals with potential anti-malarial activity against the blood stages of the rodent…”
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Comparative genomics in Plasmodium: a tool for the identification of genes and functional analysis by Thompson, J., Janse, C.J., Waters, A.P.

“…Comparative genomics allows inferences to be drawn about the coding potential of related genomes, and the evolutionary forces that have influenced genome…”
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Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model by Janse, C J, Waters, A P, Kos, J, Lugt, C B

“…The in vitro and in vivo antimalarial activity of artemisinin, artesunate and dihydroartemisinin has been compared using the Plasmodium berghei-rodent model…”
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The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti by Alavi, Y., Arai, M., Mendoza, J., Tufet-Bayona, M., Sinha, R., Fowler, K., Billker, O., Franke-Fayard, B., Janse, C.J., Waters, A., Sinden, R.E.

“…Knowledge of parasite–mosquito interactions is essential to develop strategies that will reduce malaria transmission through the mosquito vector. In this study…”
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Synchronized erythrocytic schizogony and gametocytogenesis of Plasmodium berghei in vivo and in vitro by Mons, B, Janse, C J, Boorsma, E G, Van der Kaay, H J

“…Both asexual and sexual development of Plasmodium berghei was synchronized without chemical intervention using in vitro culture techniques. Combined in vivo…”
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Plasmodium berghei: The application of cultivation and purification techniques to molecular studies of malaria parasites by Janse, C.J., Waters, A.P.

“…Species of malaria parasites that infect rodents provide models for the study of the biology of malaria parasites that infect humans. In this article, Chris…”
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Malaria Vaccines: Back to the Future? by Waters, A. P., Mota, M. M., van Dijk, M. R., Janse, C. J.

“…Malaria is the scourge of many developing countries, particularly those in sub-Saharan Africa, claiming several million lives each year. Here, Waters et al…”
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Long-term in vitro cultures of Plasmodium berghei and preliminary observations on gametocytogenesis by Janse, C J, Mons, B, Croon, J J, van der Kaay, H J

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Stable transfection of malaria parasite blood stages by Dijk, M.R. van (University of Leiden, Leiden, Netherlands.), Waters, A.P, Janse, C.J

“…Genetic manipulation of malaria parasites would revolutionize the study of this group of pathogens and have implications for vaccine and drug development. This…”
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In vitro culture of Plasmodium berghei using a new suspension system by Mons, B, Janse, C J, Croon, J J, van der Kaay, H J

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Transfection of Malaria Parasites by Waters, A.P., Thomas, A.W., van Dijk, M.R., Janse, C.J.

“…The stable genetic transformation of three phylogenetically diverse species ofPlasmodium,the parasitic etiological agent of malaria, is now possible. The…”
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Corrigendum to “The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti” [International Journal for Parasitology 33 (2003) 933–943] by Alavi, Y, Arai, M, Mendoza, J, Tufet-Bayona, M, Sinha, R, Fowler, K, Billker, O, Franke-Fayard, B, Janse, C.J, Waters, A, Sinden, R.E

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Plasmodium falciparum vaccine candidate antigen PF83/AMA-1 is expressed in the rodent malaria P. berghei: infected mice produce PF83/AMA-1 antibodies by van der Wel, A.M., Kocken, C.H.M., Dubbeld, M.A.D., Janse, C.J., Waters, A.P., Thomas, A.W.

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Chromosome translocation in Plasmodium berghei by Janse, C.J., Ramesar, J., Mons, B.

“…We decribe a chromosome translocation in a karyotype mutant of the rodent malarial parasite Plasmodium berghei. In this mutant (named EP) a small chromosome…”
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DNA synthesis in Plasmodium berghei during asexual and sexual development by Janse, C J, van der Klooster, P F, van der Kaay, H J, van der Ploeg, M, Overdulve, J P

“…DNA contents of individual stages of Plasmodium berghei were measured by direct microfluorometry after Feulgen-pararosaniline (SO2) staining. Sporozoites,…”
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Plasmodium berghei: gametocyte production, DNA content, and chromosome-size polymorphisms during asexual multiplication in vivo by Janse, C J, Boorsma, E G, Ramesar, J, van Vianen, P, van der Meer, R, Zenobi, P, Casaglia, O, Mons, B, van der Berg, F M

“…In this study the DNA content and the karyotype of clones of Plasmodium berghei, which differed in the capability to produce gametocytes, were determined. The…”
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In vitro formation of ookinetes and functional maturity of Plasmodium berghei gametocytes by Janse, C J, Mons, B, Rouwenhorst, R J, Van der Klooster, P F, Overdulve, J P, Van der Kaay, H J

“…In vitro formation of Plasmodium berghei ookinetes was studied. Gametocytes produced in vitro were obtained from heart and tail blood of Swiss mice and from…”
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Host cell specificity and schizogony of Plasmodium berghei under different in vitro conditions by Janse, C J, Boorsma, E G, Ramesar, J, Grobbee, M J, Mons, B

“…Invasion and intra-erythrocytic growth of two strains of Plasmodium berghei (ANKA and K173) were studied under different in vitro conditions. Some important…”
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Bromo-deoxyuridine is not incorporated into DNA of malaria parasites by Janse, C J, van Dijk, M, Raap, A K, Mons, B

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Plasmodium species: flow cytometry and microfluorometry assessments of DNA content and synthesis by Janse, C J, van Vianen, P H, Tanke, H J, Mons, B, Ponnudurai, T, Overdulve, J P

“…Fluorescence intensities were established by flow cytometry of different erythrocytic stages of Plasmodium berghei after staining of their DNA with…”
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