Search Results - "Janowsky, Aaron J."

Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1 by Stafford, Alexandra M, Reed, Cheryl, Baba, Harue, Walter, Nicole Ar, Mootz, John Rk, Williams, Robert W, Neve, Kim A, Fedorov, Lev M, Janowsky, Aaron J, Phillips, Tamara J

“…We identified a locus on mouse chromosome 10 that accounts for 60% of the genetic variance in methamphetamine intake in mice selectively bred for high versus…”
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Commonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other Drugs by Ozburn, Angela R., Janowsky, Aaron J., Crabbe, John C.

“…Background Alcohol abuse is comorbid with abuse of many other drugs, some with similar pharmacology and others quite different. This leads to the hypothesis of…”
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New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263 by Ofori, Edward, Onyameh, Edem K., Gonela, Uma M., Voshavar, Chandrashekhar, Bricker, Barbara, Swanson, Tracy L., Eshleman, Amy J., Schmachtenberg, Jennifer L., Bloom, Shelley H., Janowsky, Aaron J., Ablordeppey, Seth Y.

“…We have previously reported that dual 5-HT1A and 5-HT7 receptor ligands might find utility as treatment options for various CNS related conditions including…”
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Enantiomeric Separation, Absolute Configuration by X‑ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5‑HT1A and 5‑HT7A Receptors by Bricker, Barbara A., Voshavar, Chandrashekhar, Onyameh, Edem K., Gonela, Uma M., Lin, Xinsong, Swanson, Tracy L., Kozell, Laura B., Schmachtenberg, Jennifer L., Bloom, Shelley H., Janowsky, Aaron J., Ablordeppey, Seth Y.

“…We have previously identified 5-chloro-2-methyl-2-(3-(4-(pyridin-2-yl)­piperazin-1-yl)­propyl)-2,3-dihydro-1H-inden-1-one (SYA0340) as a dual 5-HT1A and 5-HT7…”
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Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT 1A and 5-HT 7A Receptors by Bricker, Barbara A, Voshavar, Chandrashekhar, Onyameh, Edem K, Gonela, Uma M, Lin, Xinsong, Swanson, Tracy L, Kozell, Laura B, Schmachtenberg, Jennifer L, Bloom, Shelley H, Janowsky, Aaron J, Ablordeppey, Seth Y

“…We have previously identified 5-chloro-2-methyl-2-(3-(4-(pyridin-2-yl)piperazin-1-yl)propyl)-2,3-dihydro-1 -inden-1-one (SYA0340) as a dual 5-HT and 5-HT…”
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[3H]Threo-(+/-)-methylphenidate binding to 3,4-dihydroxyphenylethylamine uptake sites in corpus striatum: correlation with the stimulant properties of ritalinic acid esters by Schweri, M M, Skolnick, P, Rafferty, M F, Rice, K C, Janowsky, A J, Paul, S M

“…Saturable and stereoselective binding sites for [3H]threo-(+/-)-methylphenidate were characterized in rat brain membranes. The highest density of…”
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Human serum alpha-L-fucosidase by Alhadeff, J A, Janowsky, A J

“…Human serum alpha-L-fucosidase has been purified 241 200-fold with 35% yield by an affinity chromatographic procedure utilizing…”
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Serotonergic denervation changes binding characteristics of beta-adrenoceptors in rat cortex by Manier, D H, Okada, F, Janowsky, A J, Steranka, L R, Sulser, F

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