Search Results - "Janovska, P."

WNT5A: a motility-promoting factor in Hodgkin lymphoma by Linke, F, Zaunig, S, Nietert, M M, von Bonin, F, Lutz, S, Dullin, C, Janovská, P, Beissbarth, T, Alves, F, Klapper, W, Bryja, V, Pukrop, T, Trümper, L, Wilting, J, Kube, D

“…Classical Hodgkin lymphoma (cHL) has a typical clinical manifestation, with dissemination involving functionally neighboring lymph nodes. The factors involved…”
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Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma by Linke, F, Harenberg, M, Nietert, M M, Zaunig, S, von Bonin, F, Arlt, A, Szczepanowski, M, Weich, H A, Lutz, S, Dullin, C, Janovská, P, Krafčíková, M, Trantírek, L, Ovesná, P, Klapper, W, Beissbarth, T, Alves, F, Bryja, V, Trümper, L, Wilting, J, Kube, D

“…The interaction between vascular endothelial cells (ECs) and cancer cells is of vital importance to understand tumor dissemination. A paradigmatic cancer to…”
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Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control by Medrikova, D, Jilkova, Z M, Bardova, K, Janovska, P, Rossmeisl, M, Kopecky, J

“…Objective: Adverse effects of obesity on glucose homeostasis are linked to low-grade adipose tissue inflammation and accumulation of lipids in non-adipose…”
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Anti-obesity effect of n-3 polyunsaturated fatty acids in mice fed high-fat diet is independent of cold-induced thermogenesis by Janovská, P, Flachs, P, Kazdová, L, Kopecký, J

“…Long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA) exert beneficial effects on health and they could help to prevent development of obesity and…”
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Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids by Flachs, P., Rühl, R., Hensler, M., Janovska, P., Zouhar, P., Kus, V., Macek Jilkova, Z., Papp, E., Kuda, O., Svobodova, M., Rossmeisl, M., Tsenov, G., Mohamed-Ali, V., Kopecky, J.

“…Aims/hypothesis Calorie restriction is an essential component in the treatment of obesity and associated diseases. Long-chain n- 3 polyunsaturated fatty acids…”
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Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype by Flachs, P, Adamcova, K, Zouhar, P, Marques, C, Janovska, P, Viegas, I, Jones, J G, Bardova, K, Svobodova, M, Hansikova, J, Kuda, O, Rossmeisl, M, Liisberg, U, Borkowska, A G, Kristiansen, K, Madsen, L, Kopecky, J

“…Background/objective: Futile substrate cycling based on lipolytic release of fatty acids (FA) from intracellular triacylglycerols (TAG) and their…”
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n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet by Kuda, O, Jelenik, T, Jilkova, Z, Flachs, P, Rossmeisl, M, Hensler, M, Kazdova, L, Ogston, N, Baranowski, M, Gorski, J, Janovska, P, Kus, V, Polak, J, Mohamed-Ali, V, Burcelin, R, Cinti, S, Bryhn, M, Kopecky, J

“…Aims/hypothesis Fatty acids of marine origin, i.e. docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) act as hypolipidaemics, but they do not improve…”
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Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice by Teodoro, J S, Zouhar, P, Flachs, P, Bardova, K, Janovska, P, Gomes, A P, Duarte, F V, Varela, A T, Rolo, A P, Palmeira, C M, Kopecký, J

“…Objective: Besides their role in lipid absorption, bile acids (BAs) can act as signalling molecules. Cholic acid was shown to counteract obesity and associated…”
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Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype by Flachs, P, Adamcova, K, Zouhar, P, Marques, C, Janovska, P, Viegas, I, Jones, J G, Bardova, K, Svobodova, M, Hansikova, J, Kuda, O, Rossmeisl, M, Liisberg, U, Borkowska, A G, Kristiansen, K, Madsen, L, Kopecky, J

“…This corrects the article DOI: 10.1038/ijo.2016.228…”
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Post-translational modifications regulate signalling by Ror1 by Kaucká, M., Krejčí, P., Plevová, K., Pavlová, Š., Procházková, J., Janovská, P., Valnohová, J., Kozubík, A., Pospíšilová, Š., Bryja, V.

“…Aim:  In this study, we analysed the post‐translational modification of receptor tyrosine kinase‐like orphan receptor (Ror1). Ror1 is highly upregulated in B…”
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Inducibility of triglyceride turnover in white fat – A marker of lean phenotype by Adamcova, K, Flachs, P, Zouhar, P, Bardova, K, Svobodova, M, Janovska, P, Keenan, A, Madsen, L, Jones, J, Kristiansen, K, Kopecky, J

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Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells by Dave, Zankruti, Vondálová Blanářová, Olga, Čada, Štěpán, Janovská, Pavlína, Zezula, Nikodém, Běhal, Martin, Hanáková, Kateřina, Ganji, Sri Ranjani, Krejci, Pavel, Gömöryová, Kristína, Peschelová, Helena, Šmída, Michal, Zdráhal, Zbyněk, Pavlová, Šárka, Kotašková, Jana, Pospíšilová, Šárka, Bryja, Vítězslav

“…Chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) are malignancies characterized by the dependence on B-cell receptor (BCR) signaling and by…”
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Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice by Jilkova, Z M, Hensler, M, Medrikova, D, Janovska, P, Horakova, O, Rossmeisl, M, Flachs, P, Sell, H, Eckel, J, Kopecky, J

“…Objective: Resolution of low-grade inflammation of white adipose tissue (WAT) is one of the keys for amelioration of obesity-associated metabolic dysfunctions…”
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SUN-PP004: Combined Intervention with Pioglitazone and N-3 Fatty Acids in Metformin-Treated Diabetic Patients on Postprandial Lipid Clearance and Selected Cytokines by Kopecky, J, Veleba, J, Wohl, P, Janovska, P, Kuda, O, Horakova, O, Malinska, H, Kazdova, L, Flachs, P, Bardova, K, Rossmeisl, M, Olza, J, Calder, P, Gardlo, A, Fiserova, E, Jensen, J, Bryhn, M, Pelikanova, T

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Decreased fatty acid synthesis due to mitochondrial uncoupling in adipose tissue by Rossmeisl, Martin, Syrový, Ivo, Baumruk, Filip, Flachs, Pavel, Janovska, Petra, Kopecký, Jan

“…Synthesis of fatty acid (FA) in adipose tissue requires cooperation of mitochondrial and cytoplasmic enzymes. Mitochondria are required for the production of…”
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n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet by Kuda, O., Jelenik, T., Jilkova, Z., Flachs, P., Rossmeisl, M., Hensler, M., Kazdova, L., Ogston, N., Baranowski, M., Gorski, J., Janovska, P., Kus, V., Polak, J., Mohamed-Ali, V., Burcelin, R., Cinti, S., Bryhn, M., Kopecky, J.

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Adaptive Induction of Nonshivering Thermogenesis in Muscle Rather Than Brown Fat Could Counteract Obesity by Bardova, K, Janovska, P, Vavrova, A, Kopecky, J, Zouhar, P

“…Warm-blooded animals such as birds and mammals are able to protect stable body temperature due to various thermogenic mechanisms. These processes can be…”
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An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice by Rohm, Maria, Schäfer, Michaela, Laurent, Victor, Üstünel, Bilgen Ekim, Niopek, Katharina, Algire, Carolyn, Hautzinger, Oksana, Sijmonsma, Tjeerd P, Zota, Annika, Medrikova, Dasa, Pellegata, Natalia S, Ryden, Mikael, Kulyte, Agné, Dahlman, Ingrid, Arner, Peter, Petrovic, Natasa, Cannon, Barbara, Amri, Ez-Zoubir, Kemp, Bruce E, Steinberg, Gregory R, Janovska, Petra, Kopecky, Jan, Wolfrum, Christian, Blüher, Matthias, Berriel Diaz, Mauricio, Herzig, Stephan

“…Cancer cachexia is marked by a pathological loss of fat tissue, but preventing the degradation of AMPK in this tissue helps preserve its mass in mouse models…”
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Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia by Janovska, Pavlina, Poppova, Lucie, Plevova, Karla, Plesingerova, Hana, Behal, Martin, Kaucka, Marketa, Ovesna, Petra, Hlozkova, Michaela, Borsky, Marek, Stehlikova, Olga, Brychtova, Yvona, Doubek, Michael, Machalova, Michaela, Baskar, Sivasubramanian, Kozubik, Alois, Pospisilova, Sarka, Pavlova, Sarka, Bryja, Vitezslav

“…ROR1, a receptor in the noncanonical Wnt/planar cell polarity (PCP) pathway, is upregulated in malignant B cells of chronic lymphocytic leukemia (CLL)…”
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The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling by Soldano, Alessia, Okray, Zeynep, Janovska, Pavlina, Tmejová, Kateřina, Reynaud, Elodie, Claeys, Annelies, Yan, Jiekun, Atak, Zeynep Kalender, De Strooper, Bart, Dura, Jean-Maurice, Bryja, Vítězslav, Hassan, Bassem A

“…Wnt Planar Cell Polarity (PCP) signaling is a universal regulator of polarity in epithelial cells, but it regulates axon outgrowth in neurons, suggesting the…”
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