Search Results - "Janout, Vladimir"

Is Alzheimer's disease a type 3 diabetes? A review by Janoutová, Jana, Machaczka, Ondřej, Zatloukalová, Anna, Janout, Vladimír

“…Objectives: This is a review article that deals with the question of whether type 2 diabetes is a risk factor for the development of Alzheimer's disease…”
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A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer by Fahrmann, Johannes F, Bantis, Leonidas E, Capello, Michela, Scelo, Ghislaine, Dennison, Jennifer B, Patel, Nikul, Murage, Eunice, Vykoukal, Jody, Kundnani, Deepali L, Foretova, Lenka, Fabianova, Eleonora, Holcatova, Ivana, Janout, Vladimir, Feng, Ziding, Yip-Schneider, Michele, Zhang, Jianjun, Brand, Randall, Taguchi, Ayumu, Maitra, Anirban, Brennan, Paul, Max Schmidt, C, Hanash, Samir

“…We applied a training and testing approach to develop and validate a plasma metabolite panel for the detection of early-stage pancreatic ductal adenocarcinoma…”
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Out-of-hospital cardiac arrest by Porzer, Martin, Mrazkova, Eva, Homza, Miroslav, Janout, Vladimir

“…Out-of-hospital cardiac arrest (OHCA) is a leading cause of death in developed industrial countries. The global worldwide average of OHCA incidence in adults…”
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Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer by Capello, Michela, Bantis, Leonidas E, Scelo, Ghislaine, Zhao, Yang, Li, Peng, Dhillon, Dilsher S, Patel, Nikul J, Kundnani, Deepali L, Wang, Hong, Abbruzzese, James L, Maitra, Anirban, Tempero, Margaret A, Brand, Randall, Firpo, Matthew A, Mulvihill, Sean J, Katz, Matthew H, Brennan, Paul, Feng, Ziding, Taguchi, Ayumu, Hanash, Samir M

“…CA19-9, which is currently in clinical use as a pancreatic ductal adenocarcinoma (PDAC) biomarker, has limited performance in detecting early-stage disease. We…”
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Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review by Kovalová, Martina, Gottfriedová, Nikol, Mrázková, Eva, Janout, Vladimír, Janoutová, Jana

“…Introduction: The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression, or suppressing symptoms. The…”
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Association between polymorphism rs2421943 of the insulin-degrading enzyme and schizophrenia: Preliminary report by Ambrozová, Laura, Zeman, Tomáš, Janout, Vladimír, Janoutová, Jana, Lochman, Jan, Šerý, Omar

“…Insulin-degrading enzyme (IDE) is an important gene in studies of the pathophysiology of type 2 diabetes mellitus (T2DM). Recent studies have suggested a…”
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Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors by Nickerson, Michael L, Jaeger, Erich, Shi, Yangu, Durocher, Jeffrey A, Mahurkar, Sunil, Zaridze, David, Matveev, Vsevolod, Janout, Vladimir, Kollarova, Hellena, Bencko, Vladimir, Navratilova, Marie, Szeszenia-Dabrowska, Neonilia, Mates, Dana, Mukeria, Anush, Holcatova, Ivana, Schmidt, Laura S, Toro, Jorge R, Karami, Sara, Hung, Rayjean, Gerard, Gary F, Linehan, W Marston, Merino, Maria, Zbar, Berton, Boffetta, Paolo, Brennan, Paul, Rothman, Nathaniel, Chow, Wong-Ho, Waldman, Frederic M, Moore, Lee E

“…Purpose: To provide a comprehensive, thorough analysis of somatic mutation and promoter hypermethylation of the von Hippel-Lindau ( VHL ) gene in the cancer…”
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Air Pollutants over Industrial and Non-Industrial Areas: Historical Concentration Estimates by Michalik, Jiri, Machaczka, Ondrej, Jirik, Vitezslav, Heryan, Tomas, Janout, Vladimir

“…Only a few researchers have addressed the issue of lifetime exposure related to air pollutant concentration. This study aims to develop a methodology to obtain…”
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Is Mild Cognitive Impairment a Precursor of Alzheimer's Disease? Short Review by Janoutová, Jana, Šerý, Omar, Hosák, Ladislav, Janout, Vladimír

“…Mild Cognitive Impairment (MCI) may be a precursor of Alzheimer's disease (AD). There is a boundary area between normal aging and dementia. In practice, the…”
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Comparison of official food safety control systems in member states of the European Union by Svrčinová, Pavla, Janout, Vladimír

“…In recent years increasing pressure to limit the powers of the Czech public health authorities in the field of food safety has been noticed. An approach to…”
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Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States by Wozniak, Magdalena B, Le Calvez-Kelm, Florence, Abedi-Ardekani, Behnoush, Byrnes, Graham, Durand, Geoffroy, Carreira, Christine, Michelon, Jocelyne, Janout, Vladimir, Holcatova, Ivana, Foretova, Lenka, Brisuda, Antonin, Lesueur, Fabienne, McKay, James, Brennan, Paul, Scelo, Ghislaine

“…Gene expression microarray and next generation sequencing efforts on conventional, clear cell renal cell carcinoma (ccRCC) have been mostly performed in North…”
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Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors by Moore, Lee E, Nickerson, Michael L, Brennan, Paul, Toro, Jorge R, Jaeger, Erich, Rinsky, Jessica, Han, Summer S, Zaridze, David, Matveev, Vsevolod, Janout, Vladimir, Kollarova, Hellena, Bencko, Vladimir, Navratilova, Marie, Szeszenia-Dabrowska, Neonilia, Mates, Dana, Schmidt, Laura S, Lenz, Petra, Karami, Sara, Linehan, W Marston, Merino, Maria, Chanock, Stephen, Boffetta, Paolo, Chow, Wong-Ho, Waldman, Frederic M, Rothman, Nathaniel

“…Renal tumor heterogeneity studies have utilized the von Hippel-Lindau VHL gene to classify disease into molecularly defined subtypes to examine associations…”
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Epidemiological study on more accurate diagnosis of prostate cancer by Kopecký, Josef, Navláčilová, Veronika, Janoutová, Jana, Janout, Vladimír

“…The study aimed at assessing the potential benefit of prostate health index (PHI) for early detection of prostate cancer (PCa) and the use of PHI as a marker…”
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Epidemiological of and risk factors for Alzheimer's disease: a review by Povova, Jana, Ambroz, Petr, Bar, Michal, Pavukova, Veronika, Sery, Omar, Tomaskova, Hana, Janout, Vladimir

“…Alzheimer's disease (AD) is the most common form of dementia. It is a degenerative, incurable and terminal disease. The increasing prevalence of AD is, among…”
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Alterations of glycaemia, insulin resistance and body mass index within the C-peptide optimal range in non-diabetic patients by Kron, Vladimir, Verner, Miroslav, Smetana, Pavel, Janoutova, Jana, Janout, Vladimir, Martinik, Karel

“…The study focused on changes or cut-offs of glycaemia, insulin resistance and body mass index within the C-peptide reference range (260-1730 pmol/l). The…”
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Loss of chromosome Y leads to down regulation of KDM5D and KDM6C epigenetic modifiers in clear cell renal cell carcinoma by Arseneault, Madeleine, Monlong, Jean, Vasudev, Naveen S., Laskar, Ruhina S., Safisamghabadi, Maryam, Harnden, Patricia, Egevad, Lars, Nourbehesht, Nazanin, Panichnantakul, Pudchalaluck, Holcatova, Ivana, Brisuda, Antonin, Janout, Vladimir, Kollarova, Helena, Foretova, Lenka, Navratilova, Marie, Mates, Dana, Jinga, Viorel, Zaridze, David, Mukeria, Anush, Jandaghi, Pouria, Brennan, Paul, Brazma, Alvis, Tost, Jorg, Scelo, Ghislaine, Banks, Rosamonde E., Lathrop, Mark, Bourque, Guillaume, Riazalhosseini, Yasser

“…Recent genomic studies of sporadic clear cell renal cell carcinoma (ccRCC) have uncovered novel driver genes and pathways. Given the unequal incidence rates…”
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In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium by Hosgood, H. Dean, Boffetta, Paolo, Greenland, Sander, Lee, Yuan-Chin Amy, McLaughlin, John, Seow, Adeline, Duell, Eric J., Andrew, Angeline S., Zaridze, David, Szeszenia-Dabrowska, Neonila, Rudnai, Peter, Lissowska, Jolanta, Fabiánová, Eleonóra, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Morgenstern, Hal, Rothman, Nathaniel, Hung, Rayjean J., Brennan, Paul, Lan, Qing

“…Background: Domestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide…”
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Survival and prognostic factors of early‐stage non‐small cell lung cancer in Central and Eastern Europe: A prospective cohort study by Sheikh, Mahdi, Virani, Shama, Robbins, Hilary A., Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Lissowska, Jolanta, Navratilova, Marie, Mukeriya, Anush, Ognjanovic, Miodrag, Swiatkowska, Beata, Zaridze, David, Brennan, Paul

“…Background Although early diagnosis and surgical resection of the tumor have been shown to be the most important predictors of lung cancer survival, long‐term…”
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Occupational Trichloroethylene Exposure and Renal Carcinoma Risk: Evidence of Genetic Susceptibility by Reductive Metabolism Gene Variants by MOORE, Lee E, BOFFETTA, Paolo, BENCKO, Vladimir, NAVRATILOVA, Marie, SZESZENIA-DABROWSKA, Neonila, MATES, Dana, GROMIEC, Jan, HOLCATOVA, Ivana, MERINO, Maria, CHANOCK, Stephen, CHOW, Wong-Ho, ROTHMAN, Nathaniel, KARAMI, Sara, BRENNAN, Paul, STEWART, Patricia S, HUNG, Rayjean, ZARIDZE, David, MATVEEV, Vsevolod, JANOUT, Vladimir, KOLLAROVA, Helena

“…Trichloroethylene (TCE) is a suspected renal carcinogen. TCE-associated renal genotoxicity occurs predominantly through glutathione S-transferase (GST)…”
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Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals by Lips, Esther H, Gaborieau, Valerie, McKay, James D, Chabrier, Amelie, Hung, Rayjean J, Boffetta, Paolo, Hashibe, Mia, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Field, John K, Liloglou, Triantafillos, Xinarianos, George, McLaughlin, John, Liu, Geoffrey, Skorpen, Frank, Elvestad, Maiken Bratt, Hveem, Kristian, Vatten, Lars, Study, EPIC, Benhamou, Simone, Lagiou, Pagona, Holcátová, Ivana, Merletti, Franco, Kjaerheim, Kristina, Agudo, Antonio, Castellsagué, Xavier, Macfarlane, Tatiana V, Barzan, Luigi, Canova, Cristina, Lowry, Ray, Conway, David I, Znaor, Ariana, Healy, Claire, Curado, Maria Paula, Koifman, Sergio, Eluf-Neto, Jose, Matos, Elena, Menezes, Ana, Fernandez, Leticia, Metspalu, Andres, Heath, Simon, Lathrop, Mark, Brennan, Paul

“…Background Genetic variants in 15q25 have been identified as potential risk markers for lung cancer (LC), but controversy exists as to whether this is a direct…”
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