Search Results - "Janousková, Olga"

Macroporous 2-hydroxyethyl methacrylate hydrogels of dual porosity for cell cultivation: morphology, swelling, permeability, and mechanical behavior by Přádný, Martin, Dušková-Smrčková, Miroslava, Dušek, Karel, Janoušková, Olga, Sadakbayeva, Zhansaya, Šlouf, Miroslav, Michálek, Jiří

“…Macroporous hydrogels of dual porosity based on cross-linked poly(2-hydroxyethyl methacrylate) (pHEMA) were prepared, and their swelling, mechanical responses,…”
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Quinacrine reactivity with prion proteins and prion-derived peptides by Zawada, Zbigniew, Šafařík, Martin, Dvořáková, Eva, Janoušková, Olga, Březinová, Anna, Stibor, Ivan, Holada, Karel, Bouř, Petr, Hlaváček, Jan, Šebestík, Jaroslav

“…Quinacrine is a drug that is known to heal neuronal cell culture infected with prions, which are the causative agents of neurodegenerative diseases called…”
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Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment by Etrych, Tomáš, Janoušková, Olga, Chytil, Petr

“…Targeted drug delivery using nano-sized carrier systems with targeting functions to malignant and inflammatory tissue and tailored controlled drug release…”
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Quaternized Chitosan/Heparin Polyelectrolyte Multilayer Films for Protein Delivery by Urbaniak, Tomasz, García-Briones, Gabriela S., Zhigunov, Alexander, Hladysh, Sviatoslav, Adrian, Edyta, Lobaz, Volodymyr, Krunclová, Tereza, Janoušková, Olga, Pop-Georgievski, Ognen, Kubies, Dana

“…Layer-by-layer (LbL) polyelectrolyte coatings are intensively studied as reservoirs of bioactive proteins for modulating interactions between biomaterial…”
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Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration by Filipová, Marcela, Bojarová, Pavla, Rodrigues Tavares, Marina, Bumba, Ladislav, Elling, Lothar, Chytil, Petr, Gunár, Kristýna, Křen, Vladimír, Etrych, Tomáš, Janoušková, Olga

“…The development of efficient galectin-3 (Gal-3) inhibitors draws attention in the field of anti-cancer therapy, especially due to the prominent role of extra-…”
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Membrane Permeability and Responsiveness Drive Performance: Linking Structural Features with the Antitumor Effectiveness of Doxorubicin-Loaded Stimuli-Triggered Polymersomes by Jäger, Eliézer, Černoch, Peter, Vragovic, Martina, Calumby Albuquerque, Lindomar Jose, Sincari, Vladimir, Heizer, Tomáš, Jäger, Alessandro, Kučka, Jan, Janoušková, Olga Šebestová, Pavlova, Ewa, Šefc, Luděk, Giacomelli, Fernando Carlos

“…The permeability and responsiveness of polymer membranes are absolutely relevant in the design of polymersomes for cargo delivery. Accordingly, we herein…”
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Comparison of two isolation methods of tobacco-derived extracellular vesicles, their characterization and uptake by plant and rat cells by Kocholata, Michaela, Prusova, Michaela, Auer Malinska, Hana, Maly, Jan, Janouskova, Olga

“…Plant extracellular vesicles (pEVs) derived from numerous edible sources gain a lot of attention in recent years, mainly due to the potential to efficiently…”
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Fluorescence optical imaging in anticancer drug delivery by Etrych, Tomáš, Lucas, Henrike, Janoušková, Olga, Chytil, Petr, Mueller, Thomas, Mäder, Karsten

“…In the past several decades, nanosized drug delivery systems with various targeting functions and controlled drug release capabilities inside targeted tissues…”
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Enzymatically Cross-linked Hydrogels Based on Synthetic Poly(α-amino acid)s Functionalized with RGD Peptide for 3D Mesenchymal Stem Cell Culture by Dvořáková, Jana, Trousil, Jiří, Podhorská, Bohumila, Mikšovská, Zuzana, Janoušková, Olga, Proks, Vladimír

“…Injectable hydrogel scaffolds combined with stem cell therapy represent a promising approach for minimally invasive surgical tissue repair. In this study, we…”
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A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging by Koziolová, Eva, Goel, Shreya, Chytil, Petr, Janoušková, Olga, Barnhart, Todd E, Cai, Weibo, Etrych, Tomáš

“…Here, we describe a novel polymer platform suitable for efficient diagnostics and potential theranostics based on Zr-labeled N-(2-hydroxypropyl)methacrylamide…”
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pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects by Albuquerque, Lindomar J.C., Sincari, Vladimir, Jäger, Alessandro, Kucka, Jan, Humajova, Jana, Pankrac, Jan, Paral, Petr, Heizer, Tomas, Janouškova, Olga, Davidovich, Irina, Talmon, Yeshayahu, Pouckova, Pavla, Štěpánek, Petr, Sefc, Ludek, Hruby, Martin, Giacomelli, Fernando C., Jäger, Eliézer

“…The delivery of therapeutics into sites of action by using cargo-delivery platforms potentially minimizes their premature degradation and fast clearance from…”
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Bridging the extracellular vesicle knowledge gap: insights from non-mammalian vertebrates, invertebrates, and early-diverging metazoans by Liegertová, Michaela, Janoušková, Olga

“…Extracellular vesicles (EVs) are lipid-enclosed structures that facilitate intercellular communication by transferring cargo between cells. Although…”
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Fluorescent poly[N‐(2‐hydroxypropyl) methacrylamide] nanogel by dispersion polymerization as a contrast agent for live‐cell imaging by Šálek, Petr, Zbořilová, Daniela, Pavlova, Ewa, Kočková, Olga, Konefał, Rafał, Morávková, Zuzana, Janoušková, Olga

“…Here, we report a novel dispersion polymerization for the preparation of cross‐linked poly[N‐(2‐hydroxypropyl) methacrylamide] (PHPMA)‐based nanogels in…”
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Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance by Braunová, Alena, Kostka, Libor, Sivák, Ladislav, Cuchalová, Lucie, Hvězdová, Zuzana, Laga, Richard, Filippov, Sergey, Černoch, Peter, Pechar, Michal, Janoušková, Olga, Šírová, Milada, Etrych, Tomáš

“…New amphiphilic diblock polymer nanotherapeutics serving simultaneously as a drug delivery system and an inhibitor of multidrug resistance were designed,…”
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Mucus-derived exosome-like vesicles from the Spanish slug (Arion vulgaris): taking advantage of invasive pest species in biotechnology by Liegertová, Michaela, Semerádtová, Alena, Kocholatá, Michaela, Průšová, Michaela, Němcová, Lenka, Štofik, Marcel, Kříženecká, Sylvie, Malý, Jan, Janoušková, Olga

“…The slug Arion vulgaris has attracted major attention as one of the worst invasive herbivore pests in Europe and is renowned for the stiff mucus it secretes…”
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Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics by Laga, Richard, Janoušková, Olga, Ulbrich, Karel, Pola, Robert, Blažková, Jana, Filippov, Sergey K, Etrych, Tomáš, Pechar, Michal

“…An effective chemotherapy for neoplastic diseases requires the use of drugs that can reach the site of action at a therapeutically efficacious concentration…”
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The Effect of iPS-Derived Neural Progenitors Seeded on Laminin-Coated pHEMA-MOETACl Hydrogel with Dual Porosity in a Rat Model of Chronic Spinal Cord Injury by Ruzicka, Jiri, Romanyuk, Nataliya, Jirakova, Klara, Hejcl, Ales, Janouskova, Olga, Machova, Lucia Urdzikova, Bochin, Marcel, Pradny, Martin, Vargova, Lydia, Jendelova, Pavla

“…Spinal cord injury (SCI), is a devastating condition leading to the loss of locomotor and sensory function below the injured segment. Despite some progress in…”
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Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties by Braunová, Alena, Chytil, Petr, Laga, Richard, Šírová, Milada, Machová, Daniela, Parnica, Jozef, Říhová, Blanka, Janoušková, Olga, Etrych, Tomáš

“…The study compared the physico-chemical and biological properties of a water-soluble star-like polymer nanomedicine with three micellar nanomedicines formed by…”
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Polyelectrolyte nanoparticles based on poly[N-(2-hydroxypropyl)methacrylamide-block-poly(N-(3-aminopropyl)methacrylamide] copolymers for delivery of heparin-binding proteins by García-Briones, Gabriela S., Laga, Richard, Černochová, Zulfiya, Arjona-Ruiz, Carely, Janoušková, Olga, Šlouf, Miroslav, Pop-Georgievski, Ognen, Kubies, Dana

“…[Display omitted] •Polycationic p(HPMA-block-APMA) copolymers were synthesized by RAFT polymerization.•Copolymer/Heparin NPs were formed by electrostatic…”
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Complexation of CXCL12, FGF-2 and VEGF with Heparin Modulates the Protein Release from Alginate Microbeads by Adrian, Edyta, Treľová, Dušana, Filová, Elena, Kumorek, Marta, Lobaz, Volodymyr, Poreba, Rafal, Janoušková, Olga, Pop-Georgievski, Ognen, Lacík, Igor, Kubies, Dana

“…Long-term delivery of growth factors and immunomodulatory agents is highly required to support the integrity of tissue in engineering constructs, e.g.,…”
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