Search Results - "Janota, Danielle"
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The Roles of Bone Marrow-Derived Stem Cells in Coronary Collateral Growth Induced by Repetitive Ischemia
Published in Cells (Basel, Switzerland) (06-01-2023)“…Many clinical trials have attempted to use stem cells to treat ischemic heart diseases (IHD), but the benefits have been modest. Though coronary collaterals…”
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α1‐adrenergic receptor activation mimics ischemic postconditioning
Published in The FASEB journal (01-04-2013)“…Abstract only Ischemic postconditioning has been shown to reduce injury in response to ischemia/reperfusion. Because of limitations on the clinical use of…”
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Journal Article -
3
Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation
Published in Circulation research (11-09-2015)“…RATIONALE:In the working heart, coronary blood flow is linked to the production of metabolites, which modulate tone of smooth muscle in a redox-dependent…”
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4
Mitochondrial DNA integrity and function are critical for endothelium-dependent vasodilation in rats with metabolic syndrome
Published in Basic research in cardiology (01-12-2022)“…Endothelial dysfunction in diabetes is generally attributed to oxidative stress, but this view is challenged by observations showing antioxidants do not…”
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5
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation
Published in Journal of medicinal chemistry (28-03-2024)“…The inhibition of emopamil binding protein (EBP), a sterol isomerase within the cholesterol biosynthesis pathway, promotes oligodendrocyte formation, which has…”
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6
Lack of Efficient Metabolism Adaption Caused Failure of Regenerative Cell‐Based Therapy in a Rat Model of Metabolic Syndrome
Published in The FASEB journal (01-04-2017)“…Abstract only Nearly 30–40% of patients with coronary disease show little or no coronary collateral growth and have a poorer prognosis than those with…”
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7
Catecholamine Induced Takotsubo Cardiomyopathy: The role of coronary metabolic blood flow regulation in apical ballooning
Published in The FASEB journal (01-04-2016)“…Abstract only…”
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Journal Article -
8
Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction
Published in Basic research in cardiology (01-07-2017)“…Ischemic heart disease is still the leading cause of death even with the advancement of pharmaceutical therapies and surgical procedures. Early vascularization…”
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Journal Article -
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Alpha1-adrenergic receptor activation mimics ischemic postconditioning in cardiac myocytes
Published 01-01-2014“…Ischemic postconditioning has been shown to reduce injury in response to ischemia/reperfusion. Because of limitations on the clinical use of ischemic…”
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Dissertation