Search Results - "Janoff, E"

Antibody blocks acquisition of bacterial colonization through agglutination by Roche, A M, Richard, A L, Rahkola, J T, Janoff, E N, Weiser, J N

“…Invasive infection often begins with asymptomatic colonization of mucosal surfaces. A murine model of bacterial colonization with Streptococcus pneumoniae was…”
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Pneumococcal IgA1 protease subverts specific protection by human IgA1 by Janoff, E N, Rubins, J B, Fasching, C, Charboneau, D, Rahkola, J T, Plaut, A G, Weiser, J N

“…Bacterial immunoglobulin A1 (IgA1) proteases may sabotage the protective effects of IgA. In vitro , both exogenous and endogenously produced IgA1 protease…”
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23–valent pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double-blind, randomised and placebo controlled trial by French, N, Nakiyingi, J, Carpenter, LM, Lugada, E, Watera, C, Moi, K, Moore, M, Antvelink, D, Mulder, D, Janoff, EN, Whitworth, J, Gilks, CF

“…Infection with Streptococcus pneumoniae is a frequent and serious problem for HIV-immunosuppressed adults. Vaccination is recommended in the USA and Europe,…”
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Limited expression of APRIL and its receptors prior to intestinal IgA plasma cell development during human infancy by Gustafson, C E, Higbee, D, Yeckes, A R, Wilson, C C, De Zoeten, E F, Jedlicka, P, Janoff, E N

“…The absence of immunoglobulin A (IgA) in the intestinal tract renders young infants highly susceptible to enteric infections. However, mediators of initial IgA…”
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HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages by Stevenson, M, Swingler, S, Mann, A, Jacqué, J.-M, Brichacek, B, Sasseville, V.G, Williams, K, Lackner, A.A, Janoff, E.N, Wang, R, Fisher, D

“…Infection of macrophage lineage cells is a feature of primate lentivirus replication, and several properties of primate lentiviruses seem to have evolved to…”
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Magnitude, Duration, Quality, and Function of Pneumococcal Vaccine Responses in Elderly Adults by Rubins, Jeffrey B., Puri, Amitab K. G., Loch, Joyce, Charboneau, Darlene, MacDonald, Rod, Opstad, Nancy, Janoff, Edward N.

“…The suboptimal efficacy of the currently available 23-valent pneumococcal vaccine in the growing population of adults >65 years old may be related to the…”
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Increased Plasma Human Immunodeficiency Virus Type 1 Burden following Antigenic Challenge with Pneumococcal Vaccine by Brichacek, Beda, Swindells, Susan, Janoff, Edward N., Pirruccello, Samuel, Stevenson, Mario

“…Primary factors that influence virus burden during human immunodeficiency virus type 1 (HIV-1) disease progression remain a fundamental issue in pathogenesis…”
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Determination of Antibody Responses of Elderly Adults to All 23 Capsular Polysaccharides after Pneumococcal Vaccination by RUBINS, J. B, ALTER, M, LOCH, J, JANOFF, E. N

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Pneumococcal disease during HIV infection. Epidemiologic, clinical, and immunologic perspectives by Janoff, E N, Breiman, R F, Daley, C L, Hopewell, P C

“…To characterize the epidemiology, clinical manifestations, and immunologic risk factors for infections with Streptococcus pneumoniae among persons infected…”
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Immunologic And Clinical Stages in HIV-1-Infected Ugandan Adults Are Comparable and Provide No Evidence of Rapid Progression but Poor Survival With Advanced Disease by French, N, Mujugira, A, Nakiyingi, J, Mulder, D, Janoff, E N, Gilks, C F

“…Clear understanding of the natural history of HIV-1 disease is critical for planning and developing appropriate therapeutic strategies for HIV-1-infected…”
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Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia by Rubins, J B, Charboneau, D, Paton, J C, Mitchell, T J, Andrew, P W, Janoff, E N

“…Streptococcus pneumoniae is one of the most common etiologic agents of community-acquired pneumonia, particularly bacteremic pneumonia. Pneumolysin, a…”
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Identification of hydrogen peroxide as a Streptococcus pneumoniae toxin for rat alveolar epithelial cells by DUANE, P. G, RUBINS, J. B, WEISEL, H. R, JANOFF, E. N

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Antibody Class and Subclass Responses to Pneumococcal Polysaccharides following Immunization of Human Immunodeficiency Virus-Infected Patients by Carson, Paul J., Schut, Ronald L., Simpson, Margaret L., O'Brien, James, Janoff, Edward N.

“…Antibodies of the IgM class and IgG2 and IgA2 subclasses are prominent in responses to pneumococcal polysaccharides (PPS) but may be decreased in human…”
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Systemic and Mucosal Antibody Responses to Toxin A in Patients Infected with Clostridium difficile by Johnson, Stuart, Gerding, Dale N., Janoff, Edward N.

“…The systemic and mucosal humoral response to toxin A, the primary virulencefactor of Clostridium difficile, was measured in sera and intestinal secretions from…”
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Streptococcus pneumoniae Colonization, Bacteremia, and Immune Response among Persons with Human Immunodeficiency Virus Infection by Janoff, Edward N. J, O'Brien, James, Thompson, Patricia, Ehret, Josephine, Meiklejohn, Gordon, Duvall, Gordon, Douglas, John M.

“…Although invasive pneumococcal infections are common among men infected with human immunodeficiency virus (HIV), the prevalence of pharyngeal colonization with…”
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Pneumococcal vaccination in HIV-1-infected adults in Uganda : humoral response and two vaccine failures by FRENCH, N, GILKS, C. F, MUJUGIRA, A, FASCHING, C, O'BRIEN, J, JANOFF, E. N

“…To assess the feasibility of establishing a pneumococcal vaccine trial among HIV-1-infected adults in Uganda and to characterize their responses to 23-valent…”
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Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia by Rubins, J B, Charboneau, D, Fasching, C, Berry, A M, Paton, J C, Alexander, J E, Andrew, P W, Mitchell, T J, Janoff, E N

“…Pneumolysin, the major Streptococcus pneumoniae cytotoxin, contributes to the early pathogenesis of invasive pneumococcal pneumonia by facilitating…”
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Selective neutralization of a bacterial enterotoxin by serum immunoglobulin A in response to mucosal disease by JOHNSON, S, SYPURA, W. D, GERDING, D. N, EWING, S. L, JANOFF, E. N

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Killing of Streptococcus pneumoniae by capsular polysaccharide-specific polymeric IgA, complement, and phagocytes by Janoff, E N, Fasching, C, Orenstein, J M, Rubins, J B, Opstad, N L, Dalmasso, A P

“…The role of IgA in the control of invasive mucosal pathogens such as Streptococcus pneumoniae is poorly understood. We demonstrate that human pneumococcal…”
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Response of Recent Human Immunodeficiency Virus Seroconverters to the Pneumococcal Polysaccharide Vaccine and Haemophilus influenzae Type b Conjugate Vaccine by Weiss, Peter J., Wallace, Mark R., Oldfield, Edward C., O'Brien, James, Janoff, Edward N.

“…Antibody responses in recent human immunodeficiency virus (HIV) seroconverters to 2 vaccines were studied, Twenty patients infected with HIV for < 18 months…”
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