Search Results - "Jann, Cosimo"
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Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles
Published in Nature communications (24-10-2024)“…RNA modifications play a pivotal role in the regulation of RNA chemistry within cells. Several technologies have been developed with the goal of using RNA…”
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The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress
Published in Cell reports (Cambridge) (06-04-2021)“…Most mitochondrial proteins are synthesized as precursors in the cytosol and post-translationally transported into mitochondria. The mitochondrial surface…”
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CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate
Published in Biotechnology for biofuels (10-02-2021)“…Baker's yeast is a widely used eukaryotic cell factory, producing a diverse range of compounds including biofuels and fine chemicals. The use of lignocellulose…”
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Cracking the Code: Reprogramming the Genetic Script in Prokaryotes and Eukaryotes to Harness the Power of Noncanonical Amino Acids
Published in Chemical reviews (25-09-2024)“…Over 500 natural and synthetic amino acids have been genetically encoded in the last two decades. Incorporating these noncanonical amino acids into proteins…”
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Large scale microfluidic CRISPR screening for increased amylase secretion in yeast
Published in Lab on a chip (08-08-2023)“…Key to our ability to increase recombinant protein production through secretion is a better understanding of the pathways that interact to translate, process…”
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