Search Results - "Jankowski, Michael"
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The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Published in Cell (23-12-2011)“…Innocuous touch of the skin is detected by distinct populations of neurons, the low-threshold mechanoreceptors (LTMRs), which are classified as Aβ-, Aδ-, and…”
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Dimensions of political conflict and party positions in multi-level democracies: evidence from the Local Manifesto Project
Published in West European politics (02-01-2020)“…Partisan conflicts have been frequently analysed in comparative political science research. Yet little is known about the dimensions of political conflict at…”
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Developmental impact of peripheral injury on neuroimmune signaling
Published in Brain, behavior, and immunity (01-10-2023)“…•Developmental injury uniquely impacts neuroimmune communication.•Immature immune cells may retain cellular memories of aversive stimuli.•Data discussed…”
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Hyaluronan homeostasis and its role in pain and muscle stiffness
Published in PM & R (01-12-2022)“…Hyaluronan (HA) is a glycosaminoglycan that consists of single‐chain polymers of disaccharide units of glucuronic acid and N‐acetylglucosamine. It is a chief…”
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Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination
Published in Nature neuroscience (01-08-2016)“…This study shows that the transcriptional regulator Zeb2 is required for the onset of peripheral myelination and remyelination. Zeb2 recruits HDAC1–HDAC2–NuRD…”
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Increased Expression of Transcription Factor SRY-box-Containing Gene 11 (Sox11) Enhances Neurite Growth by Regulating Neurotrophic Factor Responsiveness
Published in Neuroscience (01-07-2018)“…•Overexpression of Sox11 in sensory neurons promotes neurite growth.•Sox11 enhances the responsiveness of DRG neurons to GDNF and artemin but not NGF.•Results…”
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Purinergic signaling in peripheral nervous system glial cells
Published in Glia (01-08-2021)“…To facilitate analyses of purinergic signaling in peripheral nerve glia, we review recent literature and catalog purinergic receptor mRNA expression in…”
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Systemic administration of AAV-Slc25a46 mitigates mitochondrial neuropathy in Slc25a46−/− mice
Published in Human molecular genetics (13-03-2020)“…Abstract Mitochondrial disorders are the result of nuclear and mitochondrial DNA mutations that affect multiple organs, with the central and peripheral nervous…”
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Editorial: Insight in pediatric pain - 2023
Published in Frontiers in pain research (Lausanne, Switzerland) (21-06-2024)Get full text
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A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration
Published in Nature medicine (01-03-2018)“…Screening for small-molecule epigenetic modulators identifies HDAC3 inhibitors that promote peripheral myelin repair after nerve injury in rodents. Deficits in…”
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Comprehensive phenotyping of group III and IV muscle afferents in mouse
Published in Journal of neurophysiology (01-05-2013)“…While much is known about the functional properties of cutaneous nociceptors, relatively little is known about the comprehensive functional properties of group…”
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The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin
Published in PloS one (20-05-2019)“…In addition to large plexiform neurofibromas (pNF), NF1 patients are frequently disfigured by cutaneous neurofibromas (cNF) and are often afflicted with…”
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Vaccine alliance building blocks: a conjoint experiment on popular support for international COVID-19 cooperation formats
Published in Policy sciences (01-09-2021)“…The design principles of institutions that visibly and significantly affect citizens’ lives are likely to be politically salient. Popular support for these…”
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Dual Modulation of Nociception and Cardiovascular Reflexes during Peripheral Ischemia through P2Y1 Receptor-Dependent Sensitization of Muscle Afferents
Published in The Journal of neuroscience (06-01-2016)“…Numerous musculoskeletal pain disorders are based in dysfunction of peripheral perfusion and are often comorbid with altered cardiovascular responses to muscle…”
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Peripheral Mechanisms of Ischemic Myalgia
Published in Frontiers in cellular neuroscience (22-12-2017)“…Musculoskeletal pain due to ischemia is present in a variety of clinical conditions including peripheral vascular disease (PVD), sickle cell disease (SCD),…”
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Sex-specific role of RNA-binding protein, pAUF1, on prolonged hypersensitivity after repetitive ischemia with reperfusion injury
Published in Pain (Amsterdam) (08-10-2024)“…Repetitive ischemia with reperfusion (I/R) injury is a common cause of myalgia. Ischemia with reperfusion injuries occur in many conditions that differentially…”
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A dual role for peripheral GDNF signaling in nociception and cardiovascular reflexes in the mouse
Published in Proceedings of the National Academy of Sciences - PNAS (07-01-2020)“…Group III/IV muscle afferents transduce nociceptive signals and modulate exercise pressor reflexes (EPRs). However, the mechanisms governing afferent…”
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Early Life Nociception is Influenced by Peripheral Growth Hormone Signaling
Published in The Journal of neuroscience (19-05-2021)“…A number of cellular systems work in concert to modulate nociceptive processing in the periphery, but the mechanisms that regulate neonatal nociception may be…”
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Sex differences and mechanisms of muscle pain
Published in Current opinion in physiology (01-10-2019)“…•Men and women experience muscle pain differently. The underlying mechanisms for this difference are still not fully understood.•Peripheral mechanisms of…”
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Interleukin 1β inhibition contributes to the antinociceptive effects of voluntary exercise on ischemia/reperfusion-induced hypersensitivity
Published in Pain (Amsterdam) (01-02-2018)“…Issues of peripheral circulation have been increasingly suggested as an underlying cause of musculoskeletal pain in many conditions, including sickle cell…”
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