Search Results - "Jankowska, Elżbieta"

Rpt5-Derived Analogs Stimulate Human Proteasome Activity in Cells and Degrade Proteins Forming Toxic Aggregates in Age-Related Diseases by Cekała, Katarzyna, Trepczyk, Karolina, Witkowska, Julia, Jankowska, Elżbieta, Wieczerzak, Ewa

“…Aging and age-related diseases are associated with a decline in the capacity of protein turnover. Intrinsically disordered proteins, as well as proteins…”
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Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity by Giżyńska, Małgorzata, Witkowska, Julia, Karpowicz, Przemysław, Rostankowski, Rafał, Chocron, Estrella S, Pickering, Andrew M, Osmulski, Pawel, Gaczynska, Maria, Jankowska, Elżbieta

“…Proline- and arginine-rich peptide PR11 is an allosteric inhibitor of 20S proteasome. We modified its sequence inter alia by introducing HbYX, RYX, or RHbX…”
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The Inhibition of Serum Amyloid A Protein Aggregation by a Five-Residue Peptidomimetic: Structural and Morphological Insights by Witkowska, Julia, Skibiszewska, Sandra, Wityk, Paweł, Pilarski, Marcel, Jankowska, Elżbieta

“…Serum amyloid A (SAA) is a small protein consisting of 104 residues and, under physiological conditions, exists mainly in hexameric form. It belongs to the…”
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Pro-apoptotic action of protein-carbohydrate fraction isolated from coelomic fluid of the earthworm Dendrobaena veneta against human colon adenocarcinoma cells by Czerwonka, Arkadiusz, Fiołka, Marta J., Jędrzejewska, Katarzyna, Jankowska, Elżbieta, Zając, Adrian, Rzeski, Wojciech

“…Earthworm coelomic fluid (CF) is known as a rich source of various bioactive compounds with promising anticancer features. However, it has been demonstrated…”
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New Peptide-Based Pharmacophore Activates 20S Proteasome by Osmulski, Paweł A, Karpowicz, Przemysław, Jankowska, Elżbieta, Bohmann, Jonathan, Pickering, Andrew M, Gaczyńska, Maria

“…The proteasome is a pivotal element of controlled proteolysis, responsible for the catabolic arm of proteostasis. By inducing apoptosis, small molecule…”
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Influence of short peptides with aromatic amino acid residues on aggregation properties of serum amyloid A and its fragments by Skibiszewska, Sandra, Żaczek, Szymon, Dybala-Defratyka, Agnieszka, Jędrzejewska, Katarzyna, Jankowska, Elżbieta

“…Serum amyloid A variant 1.1 (SAA1.1) is an acute phase protein. In response to injury, inflammation or infection its production increases highly, which may…”
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Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome – insights into the enzyme activation mechanism by Witkowska, Julia, Giżyńska, Małgorzata, Grudnik, Przemysław, Golik, Przemysław, Karpowicz, Przemysław, Giełdoń, Artur, Dubin, Grzegorz, Jankowska, Elżbieta

“…Proteasomes are responsible for protein turnover in eukaryotic cells, degrading short-lived species but also removing improperly folded or oxidatively damaged…”
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Acid–Base Properties of the (1-4,18-36) Fragments of Neuropeptide K and their Mono- and Polynuclear Copper(II) Complexes Products of Metal-Catalyzed Oxidation by Błaszak, Marta, Jankowska, Elżbieta, Kowalik-Jankowska, Teresa

“…Mononuclear and polynuclear complexes of the (1-4,18-36)NPK,…”
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Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein by Pierzynowska, Karolina, Gaffke, Lidia, Jankowska, Elżbieta, Rintz, Estera, Witkowska, Julia, Wieczerzak, Ewa, Podlacha, Magdalena, Węgrzyn, Grzegorz

“…In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of…”
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Spread of nano-objects in the air as a result of switching-on a microwave by Jankowska, Elżbieta

“…Switching-on a microwave results in the creation of nano-sized particles, which can spread through the air of a given premise, e.g., room. The study was…”
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RNArchitecture: a database and a classification system of RNA families, with a focus on structural information by Boccaletto, Pietro, Magnus, Marcin, Almeida, Catarina, Żyła, Adriana, Astha, Astha, Pluta, Radosław, Bagiński, Błażej, Jankowska, Elżbieta, Dunin-Horkawicz, Stanisław, Wirecki, Tomasz K, Boniecki, Michał J, Stefaniak, Filip, Bujnicki, Janusz M

“…Abstract RNArchitecture is a database that provides a comprehensive description of relationships between known families of structured non-coding RNAs, with a…”
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Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C by Orlikowska, Marta, Jankowska, Elżbieta, Kołodziejczyk, Robert, Jaskólski, Mariusz, Szymańska, Aneta

“…Cystatins are natural inhibitors of cysteine proteases, enzymes that are widely distributed in animals, plants, and microorganisms. Human cystatin C (hCC) has…”
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Peptidomimetics Based on C-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins by Cekała, Katarzyna, Trepczyk, Karolina, Sowik, Daria, Karpowicz, Przemysław, Giełdoń, Artur, Witkowska, Julia, Giżyńska, Małgorzata, Jankowska, Elżbieta, Wieczerzak, Ewa

“…Degradation of misfolded, redundant and oxidatively damaged proteins constitutes one of the cellular processes which are influenced by the 20S proteasome…”
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Interplay between Structure and Charge as a Key to Allosteric Modulation of Human 20S Proteasome by the Basic Fragment of HIV-1 Tat Protein by Karpowicz, Przemysław, Osmulski, Paweł A, Witkowska, Julia, Sikorska, Emilia, Giżyńska, Małgorzata, Belczyk-Ciesielska, Agnieszka, Gaczynska, Maria E, Jankowska, Elżbieta

“…The proteasome is a giant protease responsible for degradation of the majority of cytosolic proteins. Competitive inhibitors of the proteasome are used against…”
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Spinal control of motor outputs by intrinsic and externally induced electric field potentials by Jankowska, Elzbieta

“…Despite numerous studies on spinal neuronal systems, several issues regarding their role in motor behavior remain unresolved. One of these issues is how…”
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Oligomers and peptidomimetics consisting of methyl 3-amino-2,3-dideoxyhexopyranosiduronic acids by Sikorska, Emilia, Tuwalska, Dorota, Karpowicz, Przemysław, Jankowska, Elżbieta, Nowacki, Andrzej, Liberek, Beata

“…In search of new foldamers, the synthesis of homo and heterooligomeric tetramers, consisting of methyl 3-amino-2,3-dideoxyhexopyranosiduronic acids, from the…”
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Designing peptidic inhibitors of serum amyloid A aggregation process by Sosnowska, Marta, Skibiszewska, Sandra, Kamińska, Emilia, Wieczerzak, Ewa, Jankowska, Elżbieta

“…Amyloid A amyloidosis is a life-threatening complication of a wide range of chronic inflammatory, infectious and neoplastic diseases, and the most common form…”
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Coordination Abilities of a Fragment Containing D 1 and H 12 Residues of Neuropeptide γ and Products of Metal-Catalyzed Oxidation by Kowalik-Jankowska, Teresa, Jankowska, Elżbieta, Kasprzykowski, Franciszek

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SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments by Piatkowski, Pawel, Jablonska, Jagoda, Zyla, Adriana, Niedzialek, Dorota, Matelska, Dorota, Jankowska, Elzbieta, Walen, Tomasz, Dawson, Wayne K, Bujnicki, Janusz M

“…RNA has been found to play an ever-increasing role in a variety of biological processes. The function of most non-coding RNA molecules depends on their…”
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Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence by Jankowska, Elżbieta, Błaszak, Marta, Kowalik-Jankowska, Teresa

“…A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A…”
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