Search Results - "Janjic, M. M."

Macrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseases by Patel, Sravan Kumar, Janjic, Jelena M

“…Inflammatory disease management poses challenges due to the complexity of inflammation and inherent patient variability, thereby necessitating patient-specific…”
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Quality by design approach identifies critical parameters driving oxygen delivery performance in vitro for perfluorocarbon based artificial oxygen carriers by Lambert, Eric, Janjic, Jelena M.

“…Perfluorocarbons (PFCs) exhibiting high solubility for oxygen are attractive materials as artificial oxygen carriers (AOC), an alternative to whole blood or…”
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Behavioral and inflammatory sex differences revealed by celecoxib nanotherapeutic treatment of peripheral neuroinflammation by Deal, Brooke, Reynolds, Laura M., Patterson, Charles, Janjic, Jelena M., Pollock, John A.

“…Neuropathic pain affects millions of people worldwide, yet the molecular mechanisms of how it develops and persists are poorly understood. Given that males…”
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Multiple Linear Regression Predictive Modeling of Colloidal and Fluorescence Stability of Theranostic Perfluorocarbon Nanoemulsions by Herneisey, Michele, Janjic, Jelena M

“…Perfluorocarbon nanoemulsions (PFC-NEs) are widely used as theranostic nanoformulations with fluorescent dyes commonly incorporated for tracking PFC-NEs in…”
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Low-dose NSAIDs reduce pain via macrophage targeted nanoemulsion delivery to neuroinflammation of the sciatic nerve in rat by Janjic, Jelena M., Vasudeva, Kiran, Saleem, Muzamil, Stevens, Andrea, Liu, Lu, Patel, Sravan, Pollock, John A.

“…Neuroinflammation involving macrophages elevates Prostaglandin E2, associated with neuropathic pain. Treatment with non-steroidal anti-inflammatory drugs…”
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RNA-Seq Reveals Sex Differences in Gene Expression during Peripheral Neuropathic Inflammation and in Pain Relief from a COX-2 Inhibiting Theranostic Nanoemulsion by Deal, Brooke, Phillips, Katherine, Crelli, Caitlin, Janjic, Jelena M, Pollock, John A

“…Given decades of neuroinflammatory pain research focused only on males, there is an urgent need to better understand neuroinflammatory pain in females. This,…”
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Sex Differences Revealed in a Mouse CFA Inflammation Model with Macrophage Targeted Nanotheranostics by Liu, Lu, Karagoz, Huseyin, Herneisey, Michele, Zor, Fatih, Komatsu, Takaaki, Loftus, Shannon, Janjic, Bratislav M, Gorantla, Vijay S, Janjic, Jelena M

“…Monocyte derived macrophages (MDMs) infiltrate sites of infection or injury and upregulate cyclooxygenase-2 (COX-2), an enzyme that stimulates prostaglandin-E2…”
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Fluorine-containing nanoemulsions for MRI cell tracking by Janjic, Jelena M., Ahrens, Eric T.

“…In this article we review the chemistry and nanoemulsion formulation of perfluorocarbons used for in vivo 19F MRI cell tracking. In this application, cells of…”
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Human B Cells Mediate Innate Anti-Cancer Cytotoxicity Through Concurrent Engagement of Multiple TNF Superfamily Ligands by Janjic, Bratislav M, Kulkarni, Aditi, Ferris, Robert L, Vujanovic, Lazar, Vujanovic, Nikola L

“…The essential innate immunity effector cells, natural killer and dendritic cells, express multiple plasma membrane-associated tumor necrosis factor (TNF)…”
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Folate-conjugated near-infrared fluorescent perfluorocarbon nanoemulsions as theranostics for activated macrophage COX-2 inhibition by Vichare, Riddhi, Crelli, Caitlin, Liu, Lu, McCallin, Rebecca, Cowan, Abree, Stratimirovic, Stefan, Herneisey, Michele, Pollock, John A., Janjic, Jelena M.

“…Activated macrophages play a critical role in the orchestration of inflammation and inflammatory pain in several chronic diseases. We present here the first…”
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Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response by Milosevic, Katarina, Stevanovic, Ivana, Bozic, Iva D, Milosevic, Ana, Janjic, Marija M, Laketa, Danijela, Bjelobaba, Ivana, Lavrnja, Irena, Savic, Danijela

“…Neuroinflammation and microglial activation, common components of most neurodegenerative diseases, can be imitated in vitro by challenging microglia cells with…”
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Injectable, reversibly thermoresponsive captopril-laden hydrogel for the local treatment of sensory loss in diabetic neuropathy by Das, Amit Chandra, Nichols, James M., Crelli, Caitlin V., Liu, Lu, Vichare, Riddhi, Pham, Hoang Vu, Gaffney, Caitlyn M., Cherry, Fisher R., Grace, Peter M., Shepherd, Andrew J., Janjic, Jelena M.

“…A major and irreversible complication of diabetes is diabetic peripheral neuropathy (DPN), which can lead to significant disability and decreased quality of…”
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Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopy by Nichols, James M, Crelli, Caitlin V, Liu, Lu, Pham, Hoang Vu, Janjic, Jelena M, Shepherd, Andrew J

“…The incidence of diabetes and diabetic peripheral neuropathy continues to rise, and studies have shown that macrophages play an important role in their…”
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Differential Expression of Neuroinflammatory mRNAs in the Rat Sciatic Nerve Following Chronic Constriction Injury and Pain-Relieving Nanoemulsion NSAID Delivery to Infiltrating Macrophages by Stevens, Andrea M, Liu, Lu, Bertovich, Dylan, Janjic, Jelena M, Pollock, John A

“…The neuroinflammatory response to peripheral nerve injury is associated with chronic pain and significant changes in the molecular expression profiles of mRNAs…”
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Testicular steroidogenesis is suppressed during experimental autoimmune encephalomyelitis in rats by Milosevic, Ana, Bjelobaba, Ivana, Bozic, Iva D., Lavrnja, Irena, Savic, Danijela, Tesovic, Katarina, Jakovljevic, Marija, Stojilkovic, Stanko S., Janjic, Marija M.

“…Multiple sclerosis (MS) is an autoimmune disease that usually occurs during the reproductive years in both sexes. Many male patients with MS show lower blood…”
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Quality by Design Approach Using Multiple Linear and Logistic Regression Modeling Enables Microemulsion Scale Up by Herneisey, Michele, Lambert, Eric, Kachel, Allison, Shychuck, Emma, Drennen, 3rd, James K, Janjic, Jelena M

“…The development of pharmaceutical nanoformulations has accelerated over the past decade. However, the nano-sized drug carriers continue to meet substantial…”
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Cyclooxgenase-2 inhibiting perfluoropoly (ethylene glycol) ether theranostic nanoemulsions-in vitro study by Patel, Sravan Kumar, Zhang, Yang, Pollock, John A, Janjic, Jelena M

“…Cylcooxgenase-2 (COX-2) expressing macrophages, constituting a major portion of tumor mass, are involved in several pro-tumorigenic mechanisms. In addition,…”
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Alterations in the Hypothalamic-Pituitary-Adrenal Axis as a Response to Experimental Autoimmune Encephalomyelitis in Dark Agouti Rats of Both Sexes by Milosevic, Ana, Milosevic, Katarina, Zivkovic, Anica, Lavrnja, Irena, Savic, Danijela, Bjelobaba, Ivana, Janjic, Marija M

“…Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, usually diagnosed during the reproductive period. Both MS…”
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Determination of heavy metals in muscle tissue of six fish species with different feeding habits from the Danube River, Belgrade—public health and environmental risk assessment by Jovanović, Dragoljub A., Marković, Radmila V., Teodorović, Vlado B., Šefer, Dragan S., Krstić, Milena P., Radulović, Stamen B., Ivanović Ćirić, Jelena S., Janjić, Jelena M., Baltić, Milan Ž.

“…The aim of this study was to investigate the presence of heavy metals/metalloids (Pb, Cd, Hg, Cu, Fe, Zn, As) in the muscle tissue of fish from the Danube…”
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Nanomedicine-driven neuropathic pain relief in a rat model is associated with macrophage polarity and mast cell activation by Saleem, Muzamil, Deal, Brooke, Nehl, Emily, Janjic, Jelena M, Pollock, John A

“…We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a…”
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