Search Results - "Janitzek, Christoph M."

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display by Singh, Susheel K, Thrane, Susan, Janitzek, Christoph M, Nielsen, Morten A, Theander, Thor G, Theisen, Michael, Salanti, Ali, Sander, Adam F

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A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA by Thrane, Susan, Janitzek, Christoph M, Agerbæk, Mette Ø, Ditlev, Sisse B, Resende, Mafalda, Nielsen, Morten A, Theander, Thor G, Salanti, Ali, Sander, Adam F

“…Placental malaria caused by Plasmodium falciparum is a major cause of mortality and severe morbidity. Clinical testing of a soluble protein-based vaccine…”
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Virus-like particle display of HER2 induces potent anti-cancer responses by Palladini, Arianna, Thrane, Susan, Janitzek, Christoph M., Pihl, Jessica, Clemmensen, Stine B., de Jongh, Willem Adriaan, Clausen, Thomas M., Nicoletti, Giordano, Landuzzi, Lorena, Penichet, Manuel L., Balboni, Tania, Ianzano, Marianna L., Giusti, Veronica, Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Lollini, Pier-Luigi, Nanni, Patrizia, Sander, Adam F.

“…Overexpression of human epidermal growth factor receptor-2 (HER2) occurs in 20-30% of invasive breast cancers. Monoclonal antibody therapy is effective in…”
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Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens by Prentoe, Jannick, Janitzek, Christoph M, Velázquez-Moctezuma, Rodrigo, Goksøyr, Louise, Olsen, Rebecca W, Fanalista, Margherita, Augestad, Elias H, Thrane, Susan, Pihl, Anne F, Gottwein, Judith M, Sander, Adam F, Bukh, Jens

“…Yearly, about 1.5 million people become chronically infected with hepatitis C virus (HCV) and for the 71 million with chronic HCV infection about 400,000 die…”
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Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature by Aves, Kara-Lee, Janitzek, Christoph M., Fougeroux, Cyrielle E., Theander, Thor G., Sander, Adam F.

“…The requirement of an undisrupted cold chain during vaccine distribution is a major economic and logistical challenge limiting global vaccine access. Modular,…”
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Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers by Prentoe, Jannick, Janitzek, Christoph M., Velázquez-Moctezuma, Rodrigo, Soerensen, Andreas, Jørgensen, Thomas, Clemmensen, Stine, Soroka, Vladislav, Thrane, Susan, Theander, Thor, Nielsen, Morten A., Salanti, Ali, Bukh, Jens, Sander, Adam F.

“…Development of B-cell-based hepatitis C virus (HCV) vaccines that induce broadly neutralizing antibodies (bNAbs) is hindered by extensive sequence diversity…”
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A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice by Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida E M, Janitzek, Christoph M, Han, Julianna, Yang, Yuhe R, Ward, Andrew B, Theander, Thor G, Nielsen, Morten A, Salanti, Ali, Thomsen, Allan R, Christensen, Jan P, Sander, Adam F

“…Due to constant antigenic drift and shift, current influenza-A vaccines need to be redesigned and administered annually. A universal flu vaccine (UFV) that…”
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The Immunogenicity of Capsid-Like Particle Vaccines in Combination with Different Adjuvants Using Different Routes of Administration by Janitzek, Christoph M, Carlsen, Philip H R, Thrane, Susan, Khanna, Vijansh M, Jakob, Virginie, Barnier-Quer, Christophe, Collin, Nicolas, Theander, Thor G, Salanti, Ali, Nielsen, Morten A, Sander, Adam F

“…Capsid-like particle (CLP) displays can be used to enhance the immunogenicity of vaccine antigens, but a better understanding of how CLP vaccines are best…”
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity by Fougeroux, Cyrielle, Goksøyr, Louise, Idorn, Manja, Soroka, Vladislav, Myeni, Sebenzile K., Dagil, Robert, Janitzek, Christoph M., Søgaard, Max, Aves, Kara-Lee, Horsted, Emma W., Erdoğan, Sayit Mahmut, Gustavsson, Tobias, Dorosz, Jerzy, Clemmensen, Stine, Fredsgaard, Laurits, Thrane, Susan, Vidal-Calvo, Elena E., Khalifé, Paul, Hulen, Thomas M., Choudhary, Swati, Theisen, Michael, Singh, Susheel K., Garcia-Senosiain, Asier, Van Oosten, Linda, Pijlman, Gorben, Hierzberger, Bettina, Domeyer, Tanja, Nalewajek, Blanka W., Strøbæk, Anette, Skrzypczak, Magdalena, Andersson, Laura F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, Tim J., Iversen, Kasper, Harritshøj, Lene H., Mordmüller, Benjamin, Ullum, Henrik, Reinert, Line S., de Jongh, Willem Adriaan, Kikkert, Marjolein, Paludan, Søren R., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Sander, Adam F.

“…The rapid development of a SARS-CoV-2 vaccine is a global priority. Here, we develop two capsid-like particle (CLP)-based vaccines displaying the…”
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Virus‐like particles displaying major house dust mite allergen Der p 2 for prophylactic allergen immunotherapy by Soongrung, Tewarit, Mongkorntanyatip, Karntichar, Peepim, Termsri, Jitthamstaporn, Sirikarn, Pitakpolrat, Patrawadee, Kaewamatawong, Theerayuth, Janitzek, Christoph M., Thrane, Susan, Sander, Adam F., Jacquet, Alain

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Bacterial superglue enables easy development of efficient virus-like particle based vaccines by Thrane, Susan, Janitzek, Christoph M, Matondo, Sungwa, Resende, Mafalda, Gustavsson, Tobias, de Jongh, Willem Adriaan, Clemmensen, Stine, Roeffen, Will, van de Vegte-Bolmer, Marga, van Gemert, Geert Jan, Sauerwein, Robert, Schiller, John T, Nielsen, Morten A, Theander, Thor G, Salanti, Ali, Sander, Adam F

“…Virus-like particles (VLPs) represent a significant advance in the development of subunit vaccines, combining high safety and efficacy. Their particulate…”
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A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine by Janitzek, Christoph M., Peabody, Julianne, Thrane, Susan, H. R. Carlsen, Philip, G. Theander, Thor, Salanti, Ali, Chackerian, Bryce, A. Nielsen, Morten, Sander, Adam F.

“…In Africa, cervical cancer and placental malaria (PM) are a major public health concern. There is currently no available PM vaccine and the marketed Human…”
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Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses by Janitzek, Christoph M, Matondo, Sungwa, Thrane, Susan, Nielsen, Morten A, Kavishe, Reginald, Mwakalinga, Steve B, Theander, Thor G, Salanti, Ali, Sander, Adam F

“…Malaria, caused by Plasmodium falciparum, continues to have a devastating impact on global health, emphasizing the great need for a malaria vaccine. The…”
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Abstract 716: A novel virus-like particle vaccine presenting HER-2 extracellular domain elicits strong immune responses against mammary carcinoma by Palladini, Arianna, Thrane, Susan, Janitzek, Christoph M., Pihl, Jessica, Clemmensen, Stine B., Jongh, Wilhelm A. de, Clausen, Thomas M., Nicoletti, Giordano, Landuzzi, Lorena, Penichet, Manuel L., Balboni, Tania, Ianzano, Marianna L., Giusti, Veronica, Theander, Thor H., Nielsen, Morten A., Salanti, Ali, Lollini, Pier-Luigi, Nanni, Patrizia, Sander, Adam F.

“…Abstract Overexpression of human epidermal growth factor receptor-2 (HER-2) occurs in about 20% of invasive breast cancers. Anti-HER-2 monoclonal antibody…”
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A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA: e0143071 by Thrane, Susan, Janitzek, Christoph M, Agerbaek, Mette Oe, Ditlev, Sisse B, Resende, Mafalda, Nielsen, Morten A, Theander, Thor G, Salanti, Ali, Sander, Adam F

“…Placental malaria caused by Plasmodium falciparum is a major cause of mortality and severe morbidity. Clinical testing of a soluble protein-based vaccine…”
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