Search Results - "Janicot, M"

Tolerability of long-term temperature controlled whole-body thermal treatment in advanced cancer-bearing dogs by Wylleman, B., Brancato, L., Gorbaslieva, I., van Zwol, E., Mori da Cunha, M. G. M. C., Benoit, J., Tierny, D., Vueghs, P., Van den Bossche, J., Rudenko, O., Janicot, M., Bogers, J.

“…Aim: In oncology, thermal therapy is the application of external heat to fight cancer cells. The goal of whole-body thermal treatment (WBTT) is to raise the…”
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An antisense oligonucleotide targeting TGF-β2 inhibits lung metastasis and induces CD86 expression in tumor-associated macrophages by Huber-Ruano, I., Raventós, C., Cuartas, I., Sánchez-Jaro, C., Arias, A., Parra, J.L., Wosikowski, K., Janicot, M., Seoane, J.

“…The transforming growth factor (TGF)-β pathway is a well-described inducer of immunosuppression and can act as an oncogenic factor in advanced tumors. Several…”
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TGF-B2 – Target to Tackle Chronic Liver Diseases Using Antisense Oligonucleotides by Dropmann, A, Korhonen, H, Janicot, M, Dooley, S, Meindl-Beinker, N

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P0441 : Tackling fibrosis using TGF-β2 targeted AONs in vivo by Dropmann, A, Korhonen, H, Jaschinski, F, Janicot, M, Meindl-Beinker, N, Dooley, S

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R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies by ARTS, J, ANGIBAUD, P, JOHNSON, D. L, ANDRIES, L, JUNG, M, JANICOT, M, VAN EMELEN, K, MARIËN, A, FLOREN, W, JANSSENS, B, KING, P, VAN DUN, J, JANSSEN, L, GEERTS, T, TUMAN, R. W

“…R306465 is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies…”
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P606 THE ROLE OF TGF-β2 IN CHRONIC LIVER DISEASE (CLD) AND HEPATOCELLULAR CARCINOMA (HCC) by Dropmann, A, Dediulia, T, Weber, S, Abshagen, K, Wieland, M, Nittka, S, Breitkopf-Heinlein, K, Korhonen, H, Jaschinski, F, Janicot, M, Meindl-Beinker, N, Dooley, S

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Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells by VANDERBORGHT, A, VALCKX, A, VAN DUN, J, GRAND-PERRET, T, DE SCHEPPER, S, VIALARD, J, JANICOT, M, ARTS, J

“…The hdm-2 oncogene is overexpressed in several types of malignancies including osteosarcomas, soft tissue sarcomas and gliomas and hdm-2 has been associated…”
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Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity by VAN HEUSDEN, J, VAN GINCKEL, R, DILLEN, L, VAN HOVE, C, WILLEMSENS, G, JANICOT, M, WOUTERS, W, BRUWIERE, H, MOELANS, P, JANSSEN, B, FLOREN, W, VAN DER LEEDE, B. J, VAN DUN, J, SANZ, G, VENET, M

“…All-trans-retinoic acid is a potent inhibitor of cell proliferation and inducer of differentiation. However, the clinical use of all-trans-retinoic acid in the…”
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Delivery of a DNAzyme targeting c-myc to HT29 colon carcinoma cells using a gold nanoparticulate approach by Tack, F, Noppe, M, Van Dijck, A, Dekeyzer, N, Van Der Leede, B J, Bakker, A, Wouters, W, Janicot, M, Brewster, M E

“…The objective of the current study was to develop cellular delivery approaches for catalytic DNA enzymes (DNAzymes) which cleave targeted messenger RNA, using…”
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Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: Toxicity, in vitro transfection and in vivo delivery by Tack, F., Bakker, A., Maes, S., Dekeyser, N., Bruining, M., Elissen-Roman, C., Janicot, M., Janssen, H.M., De Waal, B.F.M., Fransen, P.M., Lou, X., Meijer, E.W., Arien, A., Brewster, M.E.

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Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: Dendrimer synthesis, stability and oligonucleotide complexation by Tack, F., Bakker, A., Maes, S., Dekeyser, N., Bruining, M., Elissen-Roman, C., Janicot, M., Janssen, H.M., De Waal, B.F.M., Fransen, P.M., Lou, X., Meijer, E.W., Arien, A., Brewster, M.E.

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p53-dependent G2 arrest associated with a decrease in cyclins A2 and B1 levels in a human carcinoma cell line by BADIE, C, BOURHIS, J, SOBCZAK-THEPOT, J, HADDADA, H, CHIRON, M, JANICOT, M, JANOT, F, TURSZ, T, VASSAL, G

“…In vivo transfer of wild-type (wt) p53 gene via a recombinant adenovirus has been proposed to induce apoptosis and increase radiosensitivity in several human…”
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Activation of rat liver adenylate cyclase by cholera toxin requires toxin internalization and processing in endosomes by JANICOT, M, FOUQUE, F, DESBUQUOIS, B

“…Involvement of acidic cell compartments in processing and action of cholera toxin (CT) in rat liver has been examined using subcellular fractionation. Liver…”
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350 POSTER Measurement of mechanistic markers of histone deacetylase (HDAC) inhibition in samples from clinical trials by Hardcastle, A, Fong, P, Pickard, L, Arts, J, Janicot, M, Hellemans, P, DeBono, J, Aherne, W

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Promoter-cDNA-Directed Heterologous Protein Expression in Xenopus laevis Oocytes by Swick, Andrew G., Janicot, Michel, Cheneval-Kastelic, Tania, McLenithan, John C., Lane, M. Daniel

“…Heterologous proteins can be expressed in Xenopus laevis oocytes by cytoplasmic microinjection of mRNA. To circumvent limitations inherent in this approach we…”
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Activation of Glucose Uptake by Insulin and Insulin-Like Growth Factor I in Xenopus Oocytes by Janicot, Michel, Lane, M. Daniel

“…Xenopus laevis oocytes possess a glucose transport system that is activated 3- to 5-fold by insulin-like growth factor I (Ka= 3 nM) and insulin (Ka= 200-250…”
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P08.48 Therapeutic targeting of TGF- β1/2 in experimental gliomas by Papachristodoulou, A., Weller, M., Hasenbach, K., Janicot, M., Roth, P.

“…Introduction: Activation of the transforming growth factor (TGF)-β/ SMAD cascade correlates with poor prognosis in glioblastoma patients. Increased TGF-β…”
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Transcriptional Repression of the Mouse Insulin-Responsive Glucose Transporter (GLUT4) Gene by cAMP by Kaestner, Klaus H., Flores-Riveros, Jaime R., McLenithan, John C., Janicot, Michel, Lane, M. Daniel

“…Glucose uptake by adipose tissue is mediated by two glucose transporters: GLUT4, which is most abundant, and GLUT1. While GLUT1 is expressed in many tissues,…”
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The insulin-like growth factor 1 (IGF-1) receptor is responsible for mediating the effects of insulin, IGF-1, and IGF-2 in Xenopus laevis oocytes by JANICOT, M, FLORES-RIVEROS, J. R, LANE, M. D

“…Competitive hormone binding studies with membrane and partially purified receptors from Xenopus laevis oocytes revealed that the oocyte possesses high affinity…”
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SAT-385 - TGF-B2 – Target to Tackle Chronic Liver Diseases Using Antisense Oligonucleotides by Dropmann, A., Korhonen, H., Janicot, M., Dooley, S., Meindl-Beinker, N.

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