Search Results - "Jangra, Ashok"

Amelioration of Repeated Restraint Stress-Induced Behavioral Deficits and Hippocampal Anomalies with Taurine Treatment in Mice by Jangra, Ashok, Rajput, Prabha, Dwivedi, Durgesh Kumar, Lahkar, Mangala

“…Taurine, an essential neutraceutical, has been reported to exhibit antioxidant and anti-inflammatory properties. Substantial evidence indicates that prolonged…”
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7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence by Pandey, Surya Narayan, Kwatra, Mohit, Dwivedi, Durgesh Kumar, Choubey, Priyansha, Lahkar, Mangala, Jangra, Ashok

“…Rationale Alcoholism and obesity impart a deleterious impact on human health and affects the quality of life. Chronic consumption of alcohol and western diet…”
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Neuroprotective Efficacy of Edaravone against Arsenic-Induced Behavioral and Neurochemical Deficits in Rats: Amelioration of Cholinergic and Mitochondrial Functions by Arora, Mandeep K, Singh, Deepika, Tomar, Ritu, Jangra, Ashok

“…A substantial amount of evidence indicates that long-term arsenic exposure leads to various types of pathological complications, especially cognitive…”
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Naringin and Sertraline Ameliorate Doxorubicin-Induced Behavioral Deficits Through Modulation of Serotonin Level and Mitochondrial Complexes Protection Pathway in Rat Hippocampus by Kwatra, Mohit, Jangra, Ashok, Mishra, Murli, Sharma, Yogita, Ahmed, Sahabuddin, Ghosh, Pinaki, Kumar, Vikas, Vohora, Divya, Khanam, Razia

“…The present study was designed to investigate the neuroprotective effect of naringin (NR) alone as well as its combination with sertraline (SRT) against…”
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Plumbagin Alleviates Intracerebroventricular-Quinolinic Acid Induced Depression-like Behavior and Memory Deficits in Wistar Rats by Kumar Arora, Mandeep, Ratra, Anish, Asdaq, Syed Mohammed Basheeruddin, Alshamrani, Ali A, Alsalman, Abdulkhaliq J, Kamal, Mehnaz, Tomar, Ritu, Sahoo, Jagannath, Ashok, Jangra, Imran, Mohd

“…Plumbagin, a hydroxy-1,4-naphthoquinone, confers neuroprotection via antioxidant and anti-inflammatory properties. The present study aimed to assess the effect…”
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Ameliorative effect of naringin against doxorubicin-induced acute cardiac toxicity in rats by Kwatra, Mohit, Kumar, Vikas, Jangra, Ashok, Mishra, Murli, Ahmed, Sahabuddin, Ghosh, Pinaki, Vohora, Divya, Khanam, Razia

“…Context: Doxorubicin (Dox) is one of the most active chemotherapeutic agents used to treat various types of cancers. Its clinical utility is compromised due to…”
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Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus by Jangra, Ashok, Kasbe, Prajapati, Pandey, Surya Narayan, Dwivedi, Shubham, Gurjar, Satendra S, Kwatra, Mohit, Mishra, Murli, Venu, Athira K, Sulakhiya, Kunjbihari, Gogoi, Ranadeep, Sarma, Nitul, Bezbaruah, Babul K, Lahkar, Mangala

“…Mounting evidence suggests that long-term aluminum exposure results in severe toxic effects, including neurobehavioral and neurochemical anomalies. The present…”
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High-fat diet with alcohol elevate oxidative stress which cause hyperlipidemia by inducing mutation in the ANGPTL3 locus by Saini, Jyoti, Goyal, Atul Kumar, Jangra, Ashok

“…Background Angiopoietin-like 3 (ANGPTL3) is a secreted protein which predominantly expressed in the liver, and involves in upregulation of lipid metabolism…”
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Amla (Emblica officinalis) alleviates doxorubicin-induced cardiotoxicity and nephrotoxicity in rats by Arora, Mandeep Kumar, Singh, Mary, Tomar, Ritu, Singh, Lakhveer, Jangra, Ashok

“…Doxorubicin (DOX) is a widely used anticancer drug known for its significant cardiotoxic and nephrotoxic effects. Seeking remedies to mitigate these adverse…”
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Concurrent exposure to light and traffic noise pollution augments behavioral deficits in rats: Protective effect of curcumin by Sharma, Sonal, Singh, Jiten, Kumar, Dinesh, Arora, Mandeep Kumar, Jangra, Ashok

“…•Light and Traffic Noise (LTN) exposure elicit anxiety and depressive-like behavior.•LTN causes oxidative stress and inflammation in the rat…”
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Anti-fertility and abortifacient activity of hydroalcoholic fruit pulp extract of Tamarindus indica by Kaur, Mandeep, Chand Rana, Avtar, Kumar, Sunil, Kumari, Beena, Kumar, Dinesh, Jangra, Ashok

“…Background: Medicinal plants have been widely used for treatment and management of various diseases. There are many different types of commercialized synthetic…”
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Neuroprotective and acetylcholinesterase inhibitory activity of plumbagin in ICV-LPS induced behavioral deficits in rats by Jangra, Ashok, Chadha, Vaishali, Kumar, Dinesh, Kumar, Vipin, Arora, Mandeep K

“…•ICV-LPS treated rats exhibited memory deficits and anxiety-like behavior in rats.•The neuroprotective effect of plumbagin mediated through mitigation of…”
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Emergence of taurine as a therapeutic agent for neurological disorders by Jangra, Ashok, Gola, Priyanka, Singh, Jiten, Gond, Pooja, Ghosh, Swarnabha, Rachamalla, Mahesh, Dey, Abhijit, Iqbal, Danish, Kamal, Mehnaz, Sachdeva, Punya, Jha, Saurabh, Ojha, Shreesh, Kumar, Dinesh, Jha, Niraj, Chopra, Hitesh, Tan, Shing

“…Taurine is a sulfur-containing, semi-essential amino acid that occurs naturally in the body. It alternates between inflammation and oxidative stress-mediated…”
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Therapeutic potential of policosanol in the concurrent management of dyslipidemia and non-alcoholic fatty liver disease by Arora, Mandeep K., Pandey, Sudhanshu, Tomar, Ritu, Sahoo, Jagannath, Kumar, Dinesh, Jangra, Ashok

“…Background High-fat diet (HFD) possesses a major cause of cardiovascular disease, and hepatosteatosis. Unfortunately, long-term use of statins has a…”
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Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases by Sriram, Chandra Shaker, Jangra, Ashok, Madhana, Rajaram Mohanrao, Gurjar, Satendra Singh, Mohan, Pritam, Bezbaruah, Babul Kumar

“…PARP-1 activation is associated in DNA repair, cell death and inflammation. Since oxidative stress induced robust DNA damage and wide spread inflammatory…”
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Recent advances in toxicological research of di-(2-ethylhexyl)-phthalate: Focus on endoplasmic reticulum stress pathway by Singh, Jiten, Jangra, Ashok, Kumar, Dinesh

“…The plasticizer di-(2-ethylhexyl)-phthalate (DEHP) is the most significant phthalate in production, usage, and environmental occurrence. DEHP is found in…”
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Environmental toxicants and nephrotoxicity: Implications on mechanisms and therapeutic strategies by Yadav, Rachna, Kumar, Dinesh, Singh, Jiten, Jangra, Ashok

“…Kidneys are one of the most important organs in the human body. In addition to filtering 200 liters of fluid every 24 hours, the kidney also regulates…”
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Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level by Kasbe, Prajapati, Jangra, Ashok, Lahkar, Mangala

“…Mangiferin is a phytochemical primarily present in the stem, leaves and bark of Mangifera indica. It offers neuroprotection mainly through inhibition of…”
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Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade by Jangra, Ashok, Sriram, Chandra Shaker, Lahkar, Mangala

“…Oxido-nitrosative stress, neuroinflammation, and reduced level of neurotrophins are implicated in the pathophysiology of anxiety and depressive illness. A few…”
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Hepatoprotective potential of 7,8-Dihydroxyflavone against alcohol and high-fat diet induced liver toxicity via attenuation of oxido-nitrosative stress and NF-κB activation by Kumar, Dinesh, Dwivedi, Durgesh Kumar, Lahkar, Mangala, Jangra, Ashok

“…Fatty liver diseases are the most common and major health concern arises from the modern lifestyle and alcohol (ethanol) abuse. The prevalence of non-alcoholic…”
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