Search Results - "Jang, Woo Dae"

Genomic and metabolic analysis of Komagataeibacter xylinus DSM 2325 producing bacterial cellulose nanofiber by Jang, Woo Dae, Kim, Tae Yong, Kim, Hyun Uk, Shim, Woo Yong, Ryu, Jae Yong, Park, Jin Hwan, Lee, Sang Yup

“…Bacterial cellulose nanofiber (CNF) is a polymer with a wide range of potential industrial applications. Several Komagataeibacter species, including…”
Get full text

Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay by Jang, Woo Dae, Jeon, Sangeun, Kim, Seungtaek, Lee, Sang Yup

“…The COVID-19 pandemic caused by SARS-CoV-2 is an unprecedentedly significant health threat, prompting the need for rapidly developing antiviral drugs for the…”
Get full text

Systems Metabolic Engineering Strategies: Integrating Systems and Synthetic Biology with Metabolic Engineering by Choi, Kyeong Rok, Jang, Woo Dae, Yang, Dongsoo, Cho, Jae Sung, Park, Dahyeon, Lee, Sang Yup

“…Metabolic engineering allows development of microbial strains efficiently producing chemicals and materials, but it requires much time, effort, and cost to…”
Get full text

An interactive metabolic map of bio-based chemicals by Jang, Woo Dae, Kim, Gi Bae, Lee, Sang Yup

“…Metabolic engineering for the bio-based production of chemicals requires thorough understanding of metabolic reactions including enzymes, cofactors, reactants,…”
Get full text

A comprehensive metabolic map for production of bio-based chemicals by Lee, Sang Yup, Kim, Hyun Uk, Chae, Tong Un, Cho, Jae Sung, Kim, Je Woong, Shin, Jae Ho, Kim, Dong In, Ko, Yoo-Sung, Jang, Woo Dae, Jang, Yu-Sin

“…Production of industrial chemicals using renewable biomass feedstock is becoming increasingly important to address limited fossil resources, climate change and…”
Get full text

Microbial production of an aromatic homopolyester by Lee, Youngjoon, Kang, Minju, Jang, Woo Dae, Choi, So Young, Yang, Jung Eun, Lee, Sang Yup

“…A homo-aromatic polyester was produced from glucose for the first time.Aromatic polyhydroxyalkanoate (PHA) was produced to the highest titer yet achieved.3D…”
Get full text

PredAOT: a computational framework for prediction of acute oral toxicity based on multiple random forest models by Ryu, Jae Yong, Jang, Woo Dae, Jang, Jidon, Oh, Kwang-Seok

“…Acute oral toxicity of drug candidates can lead to drug development failure; thus, predicting the acute oral toxicity of small compounds is important for…”
Get full text

Microbial production of multiple short-chain primary amines via retrobiosynthesis by Kim, Dong In, Chae, Tong Un, Kim, Hyun Uk, Jang, Woo Dae, Lee, Sang Yup

“…Bio-based production of many chemicals is not yet possible due to the unknown biosynthetic pathways. Here, we report a strategy combining retrobiosynthesis and…”
Get full text

Bacterial cellulose as an example product for sustainable production and consumption by Jang, Woo Dae, Hwang, Ji Hyeon, Kim, Hyun Uk, Ryu, Jae Yong, Lee, Sang Yup

“…Life cycle of bacterial cellulose. Sustainable production and consumption of bio‐based products are showcased using bacterial cellulose as an example…”
Get full text

A deep learning approach to evaluate the feasibility of enzymatic reactions generated by retrobiosynthesis by Kim, Yeji, Ryu, Jae Yong, Kim, Hyun Uk, Jang, Woo Dae, Lee, Sang Yup

“…Retrobiosynthesis allows the designing of novel biosynthetic pathways for the production of chemicals and materials through metabolic engineering, but…”
Get full text

A safe and sustainable bacterial cellulose nanofiber separator for lithium rechargeable batteries by Gwon, Hyeokjo, Park, Kitae, Chung, Soon-Chun, Kim, Ryoung-Hee, Kang, Jin Kyu, Ji, Sang Min, Kim, Nag-Jong, Lee, Sunghaeng, Ku, Jun-Hwan, Do, Eun Cheol, Park, Sujin, Kim, Minsang, Shim, Woo Yong, Rhee, Hong Soon, Kim, Jae-Young, Kim, Jieun, Kim, Tae Yong, Yamaguchi, Yoshitaka, Iwamuro, Ryo, Saito, Shunsuke, Kim, Gahee, Jung, In-Sun, Park, Hyokeun, Lee, Chanhee, Lee, Seungyeon, Jeon, Woo Sung, Jang, Woo Dae, Kim, Hyun Uk, Lee, Sang Yup, Im, Dongmin, Doo, Seok-Gwang, Lee, Sang Yoon, Lee, Hyun Chul, Park, Jin Hwan

“…Bacterial cellulose nanofiber (BCNF) with high thermal stability produced by an ecofriendly process has emerged as a promising solution to realize safe and…”
Get full text

AnoChem: Prediction of chemical structural abnormalities based on machine learning models by Gu, Changdai, Jang, Woo Dae, Oh, Kwang-Seok, Ryu, Jae Yong

“…De novo drug design aims to rationally discover novel and potent compounds while reducing experimental costs during the drug development stage. Despite the…”
Get full text

PredPS: Attention-based graph neural network for predicting stability of compounds in human plasma by Jang, Woo Dae, Jang, Jidon, Song, Jin Sook, Ahn, Sunjoo, Oh, Kwang-Seok

“…Stability of compounds in the human plasma is crucial for maintaining sufficient systemic drug exposure and considered an essential factor in the early stages…”
Get full text

CDI Exerts Anti-Tumor Effects by Blocking the FoxM1-DNA Interaction by Jang, Woo Dae, Lee, Mi Young, Mun, Jihye, Lim, Gyutae, Oh, Kwang-Seok

“…The Forkhead box protein M1 (FoxM1) is an appealing target for anti-cancer therapeutics as this cell proliferation-associated transcription factor is…”
Get full text

Production of Carminic Acid by Metabolically Engineered Escherichia coli by Yang, Dongsoo, Jang, Woo Dae, Lee, Sang Yup

“…Carminic acid is an aromatic polyketide found in scale insects (i.e., Dactylopius coccus) and is a widely used natural red colorant. It has long been produced…”
Get full text

Applications of artificial intelligence to enzyme and pathway design for metabolic engineering by Jang, Woo Dae, Kim, Gi Bae, Kim, Yeji, Lee, Sang Yup

“…[Display omitted] •The recent applications of AI in enzyme and pathway design are described.•With AI-guided directed evolution, mutant libraries can be…”
Get full text

Design, synthesis and evaluation of 3-(2-(substituted benzyloxy)benzylidene) pyrrolidine-2,5-dione derivatives for novel ATX inhibitor by Hyeong Lee, Seung, Jin Park, Su, Young Lee, Mi, Young Choi, Jun, Dae Jang, Woo, Jang, Jidon, Hyun Lee, Jeong, Jo Lim, Chae, Oh, Kwang-Seok

“…[Display omitted] •Novel ATX inhibitor KR-40795 targets allosteric tunnel and hydrophobic pocket of enzyme.•KR-40795 demonstrates potent ATX inhibition with…”
Get full text

NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells by Lee, Seung Hyeong, Kim, Su Ah, Park, Su Jin, Lee, Mi Young, Seo, Ho Won, Issabayeva, Guldana, Hyun, Ji Young, Park, Seong Jun, Lim, Hwan Jung, Jang, Woo Dae, Lee, Jeong Hyun, Lee, Byung Ho, Oh, Kwang-Seok

“…NUAK family kinase 2 (NUAK2) is a promising target for cancer therapeutics due to its reported role in protein phosphorylation, a critical process in cancer…”
Get more information

Systematic and Comparative Evaluation of Software Programs for Template‐Based Modeling of Protein Structures by Jang, Woo Dae, Lee, Sang Mi, Kim, Hyun Uk, Lee, Sang Yup

“…Modeling protein structures is critical for understanding protein functions in various biological and biotechnological studies. Among representative protein…”
Get full text

Quantitative assessment of kinase selectivity based the water-ring network in protein binding sites using molecular dynamics simulations by Jang, Woo Dae, Lee, Myeong Hwi, Kang, Nam Sook

“…Protein kinases are implicated in a variety of diseases, such as cancer and inflammation, and are thus an important target for the pharmaceutical industry…”
Get full text