Search Results - "Jang, Sung‐Wook"

Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve by Srinivasan, Rajini, Sun, Guannan, Keles, Sunduz, Jones, Erin A, Jang, Sung-Wook, Krueger, Courtney, Moran, John J, Svaren, John

“…Myelin is essential for the rapidity of saltatory nerve conduction, and also provides trophic support for axons to prevent axonal degeneration. Two critical…”
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Suz12 binds to silenced regions of the genome in a cell-type-specific manner by Squazzo, Sharon L, O'Geen, Henriette, Komashko, Vitalina M, Krig, Sheryl R, Jin, Victor X, Jang, Sung-wook, Margueron, Raphael, Reinberg, Danny, Green, Roland, Farnham, Peggy J

“…Suz12 is a component of the Polycomb group complexes 2, 3, and 4 (PRC 2/3/4). These complexes are critical for proper embryonic development, but very few…”
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Induction of Myelin Protein Zero by Early Growth Response 2 through Upstream and Intragenic Elements by Jang, Sung-Wook, Svaren, John

“…The Mpz (myelin protein zero) gene codes for the principal component of myelin in the peripheral nervous system, and mutations in this gene cause human…”
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In vivo detection of Egr2 binding to target genes during peripheral nerve myelination by Jang, Sung‐Wook, LeBlanc, Scott E., Roopra, Avtar, Wrabetz, Lawrence, Svaren, John

“…Egr2/Krox20 is a zinc finger transactivator that regulates a diverse array of genes required for peripheral nerve myelination. Although several studies have…”
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Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes by Jang, Sung-Wook, Srinivasan, Rajini, Jones, Erin A, Sun, Guannan, Keles, Sunduz, Krueger, Courtney, Chang, Li-Wei, Nagarajan, Rakesh, Svaren, John

“…J. Neurochem. (2010) 115, 1409-1420. ABSTRACT: Myelination of peripheral nerves by Schwann cells depends upon a gene regulatory network controlled by early…”
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IgG4-Related Disease with Esophageal Involvement by Jang, Sung Wook, Jeon, Min Ho, Shin, Hyun Deok

“…We report the case of a 56-year-old man who presented with dysphagia and weight loss. An esophagoduodenoscopy revealed a severe esophageal stricture in the…”
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Active Gene Repression by the Egr2·NAB Complex during Peripheral Nerve Myelination by Mager, Gennifer M., Ward, Rebecca M., Srinivasan, Rajini, Jang, Sung-Wook, Wrabetz, Lawrence, Svaren, John

“…The Egr2/Krox20 transactivator is required for activation of many myelin-associated genes during peripheral nerve myelination by Schwann cells. However, recent…”
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Early Colon Cancer Recurring as Liver Metastasis without Local Recurrence Three Years after Complete Endoscopic Mucosal Resection by Jeon, Min Ho, Jang, Sung Wook, Lee, Chang Min, Kim, Seok Bae

“…Early colon cancer is defined as colon cancer that invades mucosal or submucosal layer regardless of lymph node invasion. Endoscopic mucosal resection can…”
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Direct Regulation of Myelin Protein Zero Expression by the Egr2 Transactivator by LeBlanc, Scott E., Jang, Sung-Wook, Ward, Rebecca M., Wrabetz, Lawrence, Svaren, John

“…During myelination of the peripheral nervous system, the myelin protein zero (Mpz) gene is induced to produce the most abundant protein component (P0) of…”
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Root canal irrigation system using remotely generated high-power ultrasound by Park, Ryeol, Choi, Minsu, Seo, Jaedeok, Park, Eun Hyun, Jang, Sung Wook, Shon, Won-Jun, Kim, Ho-Young, Kim, Wonjung

“…•A novel root canal cleaning system using remotely generated high-power ultrasound is proposed.•The cleaning performance of the proposed system is compared…”
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Identification of Drug Modulators Targeting Gene-Dosage Disease CMT1A by Jang, Sung-Wook, Lopez-Anido, Camila, MacArthur, Ryan, Svaren, John, Inglese, James

“…The structural integrity of myelin formed by Schwann cells in the peripheral nervous system (PNS) is required for proper nerve conduction and is dependent on…”
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Structure-Based Exploration of Selectivity for ATM Inhibitors in Huntington’s Disease by Van de Poël, Amanda, Toledo-Sherman, Leticia, Breccia, Perla, Cachope, Roger, Bate, Jennifer R, Angulo-Herrera, Ivan, Wishart, Grant, Matthews, Kim L, Martin, Sarah L, Peacock, Marcus, Barnard, Amy, Cox, Helen C, Jones, Graham, McAllister, George, Vater, Huw, Esmieu, William, Clissold, Cole, Lamers, Marieke, Leonard, Philip, Jarvis, Rebecca E, Blackaby, Wesley, Eznarriaga, Maria, Lazari, Ovadia, Yates, Dawn, Rose, Mark, Jang, Sung-Wook, Muñoz-Sanjuan, Ignacio, Dominguez, Celia

“…Our group has recently shown that brain-penetrant ataxia telangiectasia-mutated (ATM) kinase inhibitors may have potential as novel therapeutics for the…”
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Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington’s Disease Models by Toledo-Sherman, Leticia, Breccia, Perla, Cachope, Roger, Bate, Jennifer R, Angulo-Herrera, Ivan, Wishart, Grant, Matthews, Kim L, Martin, Sarah L, Cox, Helen C, McAllister, George, Penrose, Stephen D, Vater, Huw, Esmieu, William, Van de Poël, Amanda, Van de Bospoort, Rhea, Strijbosch, Annelieke, Lamers, Marieke, Leonard, Philip, Jarvis, Rebecca E, Blackaby, Wesley, Barnes, Karen, Eznarriaga, Maria, Dowler, Simon, Smith, Graham D, Fischer, David F, Lazari, Ovadia, Yates, Dawn, Rose, Mark, Jang, Sung-Wook, Muñoz-Sanjuan, Ignacio, Dominguez, Celia

“…Genetic and pharmacological evidence indicates that the reduction of ataxia telangiectasia-mutated (ATM) kinase activity can ameliorate mutant huntingtin…”
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Genome Editing-Enabled HTS Assays Expand Drug Target Pathways for Charcot–Marie–Tooth Disease by Inglese, James, Dranchak, Patricia, Moran, John J., Jang, Sung-Wook, Srinivasan, Rajini, Santiago, Yolanda, Zhang, Lei, Guha, Rajarshi, Martinez, Natalia, MacArthur, Ryan, Cost, Gregory J., Svaren, John

“…Copy number variation resulting in excess PMP22 protein causes the peripheral neuropathy Charcot–Marie–Tooth disease, type 1A. To broadly interrogate…”
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Relationship between fatigue severity scale and occupational injury in Korean workers by Ju, Hyeonwoo, Kim, Hwan-Cheol, Jang, Sung Wook, Won, Youna, Park, Shin-Goo, Leem, Jong-Han

“…The aim of this study is to investigate the relationship between fatigue and occupational injury. This study was conducted at a university hospital in 2014 and…”
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Association between nicotine dependency with occupational injury in Korean men by Jang, Sung Wook, Kim, Hwan-Cheol, Kim, Ji Ho, Kim, Min Sun, Won, Youna, Ju, Hyeonwoo, Kim, Hyung Doo, Choi, Go, Park, Shin-Goo, Leem, Jong-Han

“…The relationship between smoking status or second-hand smoking and occupational injuries has been the subject of considerable study, but few have studied the…”
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갈근(葛根)이 좌골신경 손상 흰쥐의 후지 근육위축에 미치는 영향 by 장승욱, 김연섭, Jang, Sung-Wook, Kim, Youn-Sub

“…This study evaluated the effects of Puerariae Radix on the skeletal muscle atrophy, Muscle atrophy was induced by the sciatic nerve transection in…”
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Adhesion properties of eco-friendly PVAc emulsion adhesive using nonphthalate plasticizer by Choi, Youn-Mee, Lee, Byoung-Ho, Park, Ji-Won, Kim, Hyun-Joong, Eom, Young Geun, Jang, Sung-Wook, Lee, Young-Kyu

“…An eco-friendly poly (vinyl acetate) emulsion adhesive was synthesized without phthalate. Four types of eco-friendly plasticizers for use in these adhesives…”
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Differential regulation of NAB corepressor genes in Schwann cells by Srinivasan, Rajini, Jang, Sung-Wook, Ward, Rebecca M, Sachdev, Shrikesh, Ezashi, Toshihiko, Svaren, John

“…Myelination of peripheral nerves by Schwann cells requires not only the Egr2/Krox-20 transactivator, but also the NGFI-A/Egr-binding (NAB) corepressors, which…”
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Flow around a pipeline and its stability in subsea trench by Lee, Seungbae, Jang, Sung-wook, Jo, Chul H, Hong, Sung-guen

“…Offshore subsea pipelines must be stable against external loadings, which are mostly due to waves and currents. To determine the stability of a subsea pipeline…”
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