Search Results - "Jang, In Jin"

Night‐time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole by Yang, Eunsol, Kim, Seokuee, Kim, Bongtae, Kim, Boram, Kim, Yechan, Park, Sung Sup, Song, Geun Seog, Yu, Kyung‐Sang, Jang, In‐Jin, Lee, SeungHwan

“…Aims Nocturnal acid breakthrough has been considered an unmet need of proton‐pump inhibitors. Tegoprazan, a novel potassium‐competitive acid blocker, is…”
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Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed‐release formulations by Park, Sooyoun, Yang, Eunsol, Kim, Byungwook, Kwon, Jihoon, Jang, In‐Jin, Lee, Seung Hwan

“…Aims The new modified‐release formulation of tegoprazan, a novel potassium‐competitive acid blocker, is expected to improve the management of acid‐related…”
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Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles by Kim, Da Jung, Yang, Jinho, Seo, Hochan, Lee, Won Hee, Ho Lee, Dong, Kym, Sungmin, Park, Young Soo, Kim, Jae Gyu, Jang, In-Jin, Kim, Yoon-Keun, Cho, Joo-Youn

“…Colorectal cancer (CRC) is the most common type cancers in the world. CRC occurs sporadically in the majority of cases, indicating the predominant cause of the…”
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Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities by Hwang, Jun Gi, Jeon, Inseung, Park, Sun Ae, Lee, Areum, Yu, Kyung‐Sang, Jang, In‐Jin, Lee, SeungHwan

“…Summary Background DWP14012 (fexuprazan), a novel potassium‐competitive acid blocker, is under development for the treatment of acid‐related disorders. Aims To…”
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Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects by Sunwoo, Jung, Ji, Sang Chun, Oh, Jaeseong, Ban, Mu Seong, Nam, Ji Yeon, Kim, Bongtae, Song, Geun Seog, Yu, Kyung‐Sang, Jang, In‐Jin, Lee, SeungHwan

“…Summary Background Potassium‐competitive acid blockers (P‐CABs) are emerging as novel treatments for acid‐related disorders including gastroesophageal reflux…”
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Evaluation of drug prescribing patterns and therapeutic drug monitoring practice using electronic medical records by Lee, Sangmi, Yoon, Seonghae, Jang, In-Jin

“…Therapeutic drug monitoring (TDM) is performed for drugs with narrow therapeutic indices. At Seoul National University Hospital (SNUH) and Seoul National…”
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Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium–glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults by Jeong, Sae Im, Kim, Yun, Nah, Jae Jin, Huh, Wan, Jang, In‐Jin, Hwang, Jun Gi, Lee, SeungHwan

“…Aims DWP16001, a novel sodium–glucose cotransporter 2 inhibitor, is under clinical development for the treatment of type 2 diabetes mellitus. This study aimed…”
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Dose‐dependent glucosuria of DWP16001, a novel selective sodium–glucose cotransporter‐2 inhibitor, in healthy subjects by Hwang, Jun Gi, Lee, SeungHwan, Huh, Wan, Han, Jumi, Oh, Jaeseong, Jang, In‐Jin, Yu, Kyung‐Sang

“…Aims DWP16001 is a novel sodium–glucose cotransporter‐2 inhibitor under development for the treatment of type 2 diabetes mellitus. This study was conducted to…”
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The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial by Park, Wan Beom, Kim, Nak-Hyun, Kim, Kye-Hyung, Lee, Seung Hwan, Nam, Won-Seok, Yoon, Seo Hyun, Song, Kyoung-Ho, Choe, Pyoeng Gyun, Kim, Nam Joong, Jang, In-Jin, Oh, Myoung-don, Yu, Kyung-Sang

“…Background. Blood levels of voriconazole, a first line therapy for invasive aspergillosis, may correlate with adverse events and treatment response. However,…”
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Usefulness of saliva for perampanel therapeutic drug monitoring by Kim, Do‐Yong, Moon, Jangsup, Shin, Yong‐Won, Lee, Soon‐Tae, Jung, Keun‐Hwa, Park, Kyung‐Il, Jung, Ki‐Young, Kim, Manho, Lee, SeungHwan, Yu, Kyung‐Sang, Jang, In‐Jin, Song, KaHeon, Chu, Kon, Lee, Sangkun

“…Objective Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) helps optimize drug management for patients with epilepsy. Salivary testing is both…”
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A safety, pharmacokinetic, pharmacogenomic and population pharmacokinetic analysis of the third‐generation EGFR TKI, olmutinib (HM61713), after single oral administration in healthy volunteers by Noh, Young Su, Yoon, Seonghae, Kim, Suk Ran, Lee, Kyung‐Tae, Jang, In‐Jin

“…The main objective of this phase I trial was to investigate pharmacokinetics (PKs) of olmutinib in three racial subjects. We also evaluate safety/tolerability…”
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Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin by Kim, Byungwook, Im, Dha Woon, Won, Heejae, Sunwoo, Jung, Han, Seung Seok, Lee, Hajeong, Kim, Dong Ki, Oh, Kook‐Hwan, Joo, Kwon Wook, Kim, Yon Su, Cho, Joo‐Youn, Lee, SeungHwan, Oh, Jaeseong, Jang, In‐Jin, Kim, Yong Chul

“…Aim To investigate the possible effect of haemodialysis (HD) on the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of evogliptin, a dipeptidyl…”
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Korean Variant Archive (KOVA): a reference database of genetic variations in the Korean population by Lee, Sangmoon, Seo, Jihae, Park, Jinman, Nam, Jae-Yong, Choi, Ahyoung, Ignatius, Jason S., Bjornson, Robert D., Chae, Jong-Hee, Jang, In-Jin, Lee, Sanghyuk, Park, Woong-Yang, Baek, Daehyun, Choi, Murim

“…Despite efforts to interrogate human genome variation through large-scale databases, systematic preference toward populations of Caucasian descendants has…”
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ST2 blockade mitigates peritoneal fibrosis induced by TGF‐β and high glucose by Kim, Yong Chul, Kim, Kyu Hong, Lee, Sunhwa, Jo, Ji‐won, Park, Jae Yoon, Park, Mi‐seon, Tsogbadrakh, Bodokhsuren, Lee, Jung Pyo, Lee, Jae Wook, Kim, Dong Ki, Oh, Kook‐Hwan, Jang, In‐Jin, Kim, Yon Su, Cha, Ran‐hui, Yang, Seung Hee

“…Peritoneal fibrosis (PF) is an intractable complication of peritoneal dialysis (PD) that leads to peritoneal membrane failure. This study investigated the role…”
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Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians by Hasunuma, Tomoko, Tohkin, Masahiro, Kaniwa, Nahoko, Jang, In‐Jin, Yimin, Cui, Kaneko, Masaru, Saito, Yoshiro, Takeuchi, Masahiro, Watanabe, Hiroshi, Yamazoe, Yasushi, Uyama, Yoshiaki, Kawai, Shinichi

“…Aim To examine whether strict control of clinical trial conditions could reduce apparent differences of pharmacokinetic (PK) parameters among ethnic groups…”
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Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects by Kim, Yun, Lee, Sangwon, Kim, Yohan, Jang, In‐Jin, Lee, SeungHwan

“…Baloxavir marboxil, a novel influenza therapeutic agent, is a prodrug rapidly metabolized into its active form, baloxavir acid, which inhibits cap‐dependent…”
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ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy by Kim, Hee‐Jun, Im, Seock‐Ah, Keam, Bhumsuk, Ham, Hye Seon, Lee, Kyung Hun, Kim, Tae Yong, Kim, Yu Jung, Oh, Do‐Youn, Kim, Jee Hyun, Han, Wonshik, Jang, In‐Jin, Kim, Tae‐You, Park, In Ae, Noh, Dong Young

“…Expression of the adenosine triphosphate‐binding cassette B1 (ABCB1) transporter and P‐glycoprotein are associated with resistance to anticancer drugs. The…”
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Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects by Tsuda, Yasuhiro, Grimaldi, Christine, Huang, Fenglei, Benediktus, Ewald, Yagi, Nobutaka, Padula, Steven J., Jang, In‐Jin, Steffgen, Jürgen

“…Aims To evaluate the safety, pharmacokinetics and pharmacodynamics of BI 655064 in healthy Chinese and Japanese subjects after administration of single doses…”
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Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy by Jang, Yoonhyuk, Yoon, Seonghae, Kim, Tae-Joon, Lee, SeungHwan, Yu, Kyung-Sang, Jang, In-Jin, Chu, Kon, Lee, Sang Kun

“…This study aimed to develop a pharmacokinetic (PK) model of oxcarbazepine (OXC) and analyse the relationship between monohydroxylated derivative (MHD), an…”
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Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium–glucose cotransporter 2 inhibitor and metformin in healthy subjects by Kim, Byungwook, Huh, Ki Young, Hwang, Jun Gi, Nah, JaeJin, Huh, Wan, Cho, Jae Min, Jang, In‐Jin, Yu, Kyung‐Sang, Kim, Yun, Lee, SeungHwan

“…Aims DWP16001 is a novel sodium–glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes with selective and sustained sodium–glucose…”
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