Search Results - "Jang, Hyun Hee"

Investigation of Oxidation Methods for Waste Soy Sauce Treatment by Jang, Hyun-Hee, Seo, Gyu-Tae, Jeong, Dae-Woon

“…To obtain a suitable oxidation method for removing the color and lowering the chemical oxygen demand (COD) of waste soy sauce, Fenton (Fe ), Fenton-like (Fe ),…”
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Investigation by site‐directed mutagenesis of the role of cytochrome P450 2B4 non‐active‐site residues in protein–ligand interactions based on crystal structures of the ligand‐bound enzyme by Wilderman, P. Ross, Gay, Sean C., Jang, Hyun‐Hee, Zhang, Qinghai, Stout, C. David, Halpert, James R.

“…Residues located outside the active site of cytochromes P450 2B have exhibited importance in ligand binding, structural stability and drug metabolism. However,…”
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Effects of sildenafil on nanostructural and nanomechanical changes in mitochondria in an ischaemia-reperfusion rat model by Lee, Kyung Hye, Kwon, Sung Jin, Woo, Jong-Shin, Lee, Gi-Ja, Lee, So-Ra, Jang, Hyun-Hee, Kim, Hyun Soo, Kim, Jung Wook, Park, Hun Kuk, Cho, Kyu Seok, Kim, Weon

“…Summary Sildenafil exerts cardioprotective effects by activating the opening of mitochondrial ATP‐sensitive potassium channels to attenuate…”
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Functional and conformational modulation of human cytochrome P450 1B1 by anionic phospholipids by Jang, Hyun-Hee, Kim, Dong-Hyun, Ahn, Taeho, Yun, Chul-Ho

“…We investigated the interaction of human P450 1B1 (CYP1B1) with various phospholipid bilayers using the N-terminally deleted (Δ2–4)CYP1B1 and (Δ2–26)CYP1B1…”
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Increase of human CYP1B1 activities by acidic phospholipids and kinetic deuterium isotope effects on CYP1B1 substrate oxidation by Jang, Hyun-Hee, Kim, So-Young, Kang, Ji-Yeon, Park, Seon Ha, Ryu, Sang Hoon, Ahn, Taeho, Yun, Chul-Ho

“…The effect of phospholipids on the kinetic parameters of three substrates, 7-ethoxy-4 -(trifluoromethyl)coumarin (7-EFC), 7-ethoxycoumarin (7-EC) and…”
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Beta sheet 2–alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners by Jang, Hyun-Hee, Jamakhandi, Arvind P., Sullivan, Shane Z., Yun, Chul-Ho, Hollenberg, Paul F., Miller, Grover P.

“…As a promiscuous redox partner, the biological role of cytochrome P450 reductase (CPR) depends significantly on protein–protein interactions. We tested a…”
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Additional Effects of Back-Shu Electroacupuncture and Moxibustion in Cardioprotection of Rat Ischemia-Reperfusion Injury by Kim, Woo-shik, Lee, Sanghoon, Kim, Weon, Jang, Hyun-Hee, Lee, Kyung Hye, Lee, So Ra, Woo, Jong Shin, Kim, Hyun Soo, Park, Jimin, Yoon, Kanghyun, Kathy Lee, Seung Min, Kim, Jin-Bae

“…Many preclinical studies show that electroacupuncture (EA) on PC6 and ST36 can reduce infarct size after ischemia-reperfusion (IR) injury. Yet studies to…”
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Bone Marrow-Derived Vasculogenic Mesenchymal Stem Cells Enhance In Vitro Angiogenic Sprouting of Human Umbilical Vein Endothelial Cells by Jang, Hyun Hee, Son, Youngsook, Park, Gabee, Park, Ki-Sook

“…Vasculogenic properties of bone marrow-derived mesenchymal stem cells (MSCs) have been reported, but it is still unclear whether the vasculogenic properties…”
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Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis by Lee, Hae-In, Ahn, Min-Joo, Yoo, Jae-Kwang, Ahn, So-Hee, Park, Seon Young, Seo, Hyangmi, Kim, Moon-Ju, Lee, Yu Jeong, Jang, Hyun Hee, Shim, Seung Cheol, Won, Eun Jeong, Park, Cheolhyoung, Choi, Chulhee, Kim, Tae-Jong

“…This study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an exosome-based NF-κB…”
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Regioselective hydroxylation pathway of tenatoprazole to produce human metabolites by Bacillus megaterium CYP102A1 by Le, Thien-Kim, Cha, Gun-Su, Jang, Hyun-Hee, Nguyen, Thi Huong Ha, Doan, Tiep Thi My, Lee, Young Ju, Park, Ki Deok, Shin, Yumi, Kim, Dong-Hyun, Yun, Chul-Ho

“…[Display omitted] •CYP102A1 is a cytochrome P450 monooxygenase from Bacillus megaterium.•A major hydroxylation product of tenatoprazole by CYP102A1 is 5’-OH…”
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Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals by Choi, Eun-Yong, M.D, Lee, Hansongyi, M.S, Woo, Jong Shin, M.D., Ph.D, Jang, Hyun Hee, M.S, Hwang, Seung Joon, M.D, Kim, Hyun Soo, M.D, Kim, Woo-Sik, M.D., Ph.D, Kim, Young-Seol, M.D., Ph.D, Choue, Ryowon, Ph.D, Cha, Yong-Jun, Ph.D, Yim, Jung-Eun, Ph.D, Kim, Weon, M.D., Ph.D

“…Abstract Objectives Acute or chronic intake of polyphenol-rich foods has been reported to improve endothelial function. Quercetin, found abundantly in onion,…”
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Fretibacterium Species to Fusobacterium periodonticum Ratio as a Potential Biomarker of Periodontitis Based on Salivary Microbiome Profiling by Oh, Eun Ji, Jang, Hyun Hee, Park, Sangwon, Lim, Hyun-Pil, Yun, Kwi-Dug, Jang, Woohyung, Kim, Ok-Su, Park, Chan, Won, Eun Jeong

“…KCI Citation Count: 0…”
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A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus caprae , Corynebacterium , and Cutibacterium Species by Won, Eun Jeong, Jang, Hyun Hee, Park, Hansoo, Kim, Seong Jin

“…Little is known about the scalp bacterial composition of alopecia areata (AA) patients. The aim of this study was to investigate the differences in the scalp…”
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Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6 by Wilderman, P. Ross, Shah, Manish B, Jang, Hyun-Hee, Stout, C. David, Halpert, James R

“…Despite recent advances in atomic-level understanding of drug and inhibitor interactions with human cytochromes P450, the decades-old questions of chemical and…”
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Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol by Kim, Don-Kyu, Kim, Yong-Hoon, Jang, Hyun-Hee, Park, Jinyoung, Kim, Jung Ran, Koh, Minseob, Jeong, Won-Il, Koo, Seung-Hoi, Park, Tae-Sik, Yun, Chul-Ho, Park, Seung Bum, Chiang, John Y L, Lee, Chul-Ho, Choi, Hueng-Sik

“…The hepatic endocannabinoid system and cytochrome P450 2E1 (CYP2E1), a key enzyme causing alcohol-induced reactive oxygen species (ROS) generation, are major…”
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Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3 by Le, Thien-Kim, Jang, Hyun-Hee, Nguyen, Ha Thi Huong, Doan, Tiep Thi My, Lee, Ga-Young, Park, Ki Deok, Ahn, Taeho, Joung, Young Hee, Kang, Hyung-Sik, Yun, Chul-Ho

“…[Display omitted] •A set of CYP102A1 mutants can catalyze regioselective hydroxylation of polydatin.•Major product of polydatin hydroxylation is astringin, a…”
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The effectiveness of tumor necrosis factor-α blocker therapy in patients with axial spondyloarthritis who failed conventional treatment: a comparative study focused on improvement in ASAS Health Index by Choi, Ah-Ra, Park, Ki-Jeong, Kang, Ji-Hyoun, Lee, Yu Jeong, Jang, Hyun Hee, Kim, Moon-Ju, Kim, Tae-Jong

“…Objective: The purpose of this study is to evaluate the impact of tumor necrosis factor (TNF)-α blocker therapy on the Assessment of SpondyloArthritis…”
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Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison by Shah, Manish B, Wilderman, P Ross, Liu, Jingbao, Jang, Hyun-Hee, Zhang, Qinghai, Stout, C David, Halpert, James R

“…X-ray crystal structures of complexes of cytochromes CYP2B6 and CYP2A6 with the monoterpene sabinene revealed two distinct binding modes in the active sites…”
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Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes by Jang, Hyun-Hee, Liu, Jingbao, Lee, Ga-Young, Halpert, James R., Wilderman, P. Ross

“…The functional importance of a peripheral pocket found in previously published X-ray crystal structures of CYP2B4 and CYP2B6 was probed using a biophysical…”
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Gut Bacterial Metabolites from Tryptophan and Phenylalanine Induce Melatonin Synthesis and Extend Sleep Duration in Mice by Lee, Ji-Hyeok, Hwang, Su Jung, Ham, Song Lim, Kim, Jonghwan, Bang, Hye Jung, Park, Joon-Suk, Jang, Hyun-Hee, Kim, Tae Yang, Park, Jeong Woo, Seo, Young Rok, Kim, Byeong Soo, Kim, Gon Sup, Lee, Hyo-Jong, Kim, Chung Sub

“…The human gut microbiota significantly influences various physiological systems, including immune, nervous, and metabolic systems. Recent studies suggest that…”
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