Search Results - "Jang, Geunhyo"
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Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease
Published in Frontiers in immunology (25-10-2018)“…Inflammatory bowel disease (IBD) is a chronic inflammatory condition caused by an aberrant immune response to microbial components of the gastrointestinal…”
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Kinetics of adult hematopoietic stem cell differentiation in vivo
Published in The Journal of experimental medicine (05-11-2018)“…Adult hematopoiesis has been studied in terms of progenitor differentiation potentials, whereas its kinetics in vivo is poorly understood. We combined…”
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Clonal barcoding of endogenous adult hematopoietic stem cells reveals a spectrum of lineage contributions
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-2024)“…The hierarchical model of hematopoiesis posits that self-renewing, multipotent hematopoietic stem cells (HSCs) give rise to all blood cell lineages. While this…”
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1012 – FUNCTION AND MALFUNCTION OF HEMATOPOIETIC STEM CELLS IN THEIR NATIVE HOSTS
Published in Experimental hematology (01-08-2024)“…Genetic approaches to the study of hematopoietic stem cell (HSC) function in their native hosts led to conflicting notions about the rate and lineage spectrum…”
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Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs, comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear…”
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Stem cell decoupling underlies impaired lymphoid development during aging
Published in Proceedings of the National Academy of Sciences - PNAS (30-05-2023)“…Mammalian aging is associated with multiple defects of hematopoiesis, most prominently with the impaired development of T and B lymphocytes. This defect is…”
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Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties
Published in Science immunology (27-03-2020)“…Tissue-resident macrophages are a diverse population of cells that perform specialized functions including sustaining tissue homeostasis and tissue…”
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Nerve associated lung resident interstitial macrophage subset exhibits distinct localization and polarization
Published in The Journal of immunology (1950) (01-05-2020)“…Tissue resident macrophages are a diverse population of cells that perform specialized functions: sustaining tissue homeostasis and tissue surveillance. Here…”
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Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
Published in Science immunology (12-04-2024)“…The development of dendritic cells (DCs), including antigen-presenting conventional DCs (cDCs) and cytokine-producing plasmacytoid DCs (pDCs), is controlled by…”
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