Search Results - "Jang, Byungki"

Mass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains by Ishigami, Akihito, Masutomi, Hirofumi, Handa, Setsuko, Nakamura, Megumi, Nakaya, Shuuichi, Uchida, Yoshiaki, Saito, Yuko, Murayama, Shigeo, Jang, Byungki, Jeon, Yong-Chul, Choi, Eun-Kyoung, Kim, Yong-Sun, Kasahara, Yasushi, Maruyama, Naoki, Toda, Tosifusa

“…Peptidylarginine deiminases (PADs) are posttranslational modification enzymes that convert protein arginine to citrulline residues in a calcium ion‐dependent…”
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Radotinib Decreases Prion Propagation and Prolongs Survival Times in Models of Prion Disease by Choi, Yeong-Gon, Jang, Byungki, Park, Jeong-Ho, Choi, Min-Woo, Lee, Gong Yeal, Cho, Dae Jin, Kim, Hong Youp, Lim, Hae Kyoung, Lee, Won Jae, Choi, Eun-Kyoung, Kim, Yong-Sun

“…The conversion of cellular prion protein (PrP ) into pathogenic prion isoforms (PrP ) and the mutation of are definite causes of prion diseases. Unfortunately,…”
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Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells by Kim, Jong‐Seok, Kim, Woo Sik, Choi, Han‐Gyu, Jang, Byungki, Lee, Keehoon, Park, Jong‐Hwan, Kim, Hwa‐Jung, Cho, Sang‐Nae, Shin, Sung Jae

“…RpfB regulates innate immunity and activates adaptive immunity through TLR4; a potential design for more effective vaccines. The failure of Mycobacterium bovis…”
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Induction of peptidylarginine deiminase 2 and 3 by dibutyryl cAMP via cAMP‐PKA signaling in human astrocytoma U‐251MG cells by Masutomi, Hirofumi, Kawashima, Saki, Kondo, Yoshitaka, Uchida, Yoshiaki, Jang, Byungki, Choi, Eun‐Kyoung, Kim, Yong‐Sun, Shimokado, Kentaro, Ishigami, Akihito

“…Peptidylarginine deiminases (PADs) are posttranslational modification enzymes that citrullinate (deiminate) protein arginine residues in a calcium‐dependent…”
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Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis by Kim, Sung-Eun, Park, Ji Won, Kim, Mo-Jong, Jang, Byungki, Jeon, Yong-Chul, Kim, Hee-Jun, Ishigami, Akihito, Kim, Hyoung Su, Suk, Ki Tae, Kim, Dong Joon, Park, Choong Kee, Choi, Eun-Kyoung, Jang, Myoung-Kuk

“…Hepatic stellate cells (HSCs) play pivotal roles in hepatic fibrosis as they synthesize glial fibrillary acidic protein (GFAP), which is increased in activated…”
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The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells by Jang, Byungki, Ishigami, Akihito, Kim, Yong-Sun, Choi, Eun-Kyoung

“…The conversion of peptidylarginine into peptidylcitrulline by calcium-dependent peptidylarginine deiminases (PADs) has been implicated in the pathogenesis of a…”
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Measles Virus Neutralizing Antibody Response and Durability Two Years after One or Two Doses of Measles-Mumps-Rubella Vaccine among Young Seronegative Healthcare Workers by Jang, Byungki, Kim, Han Wool, Kim, Han-Sung, Park, Ji Young, Seo, Hyeonji, Kim, Yong Kyun

“…Although there have been several studies regarding the immunogenicity of one or two booster doses of the measles−mumps−rubella (MMR) vaccine in…”
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Impairment of Neuronal Mitochondrial Quality Control in Prion-Induced Neurodegeneration by Kim, Mo-Jong, Kim, Hee-Jun, Jang, Byungki, Kim, Hyun-Ji, Mostafa, Mohd Najib, Park, Seok-Joo, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Mitochondrial dynamics continually maintain cell survival and bioenergetics through mitochondrial quality control processes (fission, fusion, and mitophagy)…”
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Calsenilin, a Presenilin Interactor, Regulates RhoA Signaling and Neurite Outgrowth by Kim, Hee-Jun, Lee, Won-Haeng, Kim, Mo-Jong, Shin, Sunmee, Jang, Byungki, Park, Jae-Bong, Wasco, Wilma, Buxbaum, Joseph D, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Calsenilin modulates A-type potassium channels, regulates presenilin-mediated γ-secretase activity, and represses prodynorphin and genes expression. RhoA is…”
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Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases by Jang, Byungki, Jeon, Yong-Chul, Choi, Jin-Kyu, Park, Mira, Kim, Jae-Il, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I, Kim, Yong-Sun, Choi, Eun-Kyoung

“…The citrullination of enolase by PAD (peptidylarginine deiminase) has emerged as an important post-translational modification in human disorders; however, the…”
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Biochemical properties of cytochrome c nitrated by peroxynitrite by Jang, Byungki, Han, Sanghwa

“…Nitration of tyrosine residues is taken as evidence for intracellular formation of peroxynitrite. Cytochrome c (cyt c) can be nitrated by peroxynitrite and…”
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Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease by Jin, Jae-Kwang, Jang, Byungki, Jin, Hyoung Tae, Choi, Eun-Kyoung, Jung, Cha-Gyun, Akatsu, Hiroyasu, Kim, Jae-Il, Carp, Richard I, Kim, Yong-Sun

“…PrPSc is formed from a normal glycosylphosphatidylinositol (GPI)-anchored prion protein (PrPC) by a posttranslational modification. Most GPI-anchored proteins…”
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Subcellular Localization of Peptidylarginine Deiminase 2 and Citrullinated Proteins in Brains of Scrapie-Infected Mice: Nuclear Localization of PAD2 and Membrane Fraction-Enriched Citrullinated Proteins by Jang, Byungki, Shin, Hae-Young, Choi, Jin-Kyu, Nguyen, Du Phuong Thao, Jeong, Byung-Hoon, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Peptidylarginine deiminase (PAD) and citrullinated proteins have emerged as key molecules in various human diseases, but detailed subcellular localizations of…”
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Accumulation of Citrullinated Proteins by Up-Regulated Peptidylarginine Deiminase 2 in Brains of Scrapie-Infected Mice by Jang, Byungki, Kim, Eunah, Choi, Jin-Kyu, Jin, Jae-Kwang, Kim, Jae-Il, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Peptidylarginine deiminases (PADs), which are a group of posttranslational modification enzymes, are involved in protein citrullination (deimination) by the…”
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Amelioration of Toll-like Receptor-4 Signaling and Promotion of Mitochondrial Function by Mature Silkworm Extracts in Ex Vivo and in Vitro Macrophages by Phan, Trinh Yen Binh, Jang, Byungki, Kang, Sang-Kuk, Seo, Jongbok, Kim, Seong-Ryul, Kim, Kee-Young, Koh, Young Ho

“…Objectives: The unknown immune-enhancing effects of steamed mature silkworms (Bombyx mori L.), known as HongJam (HJ), were investigated. Methods: Supercritical…”
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Peptidylarginine deiminase inhibition impairs Toll‐like receptor agonist‐induced functional maturation of dendritic cells, resulting in the loss of T cell–proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings by Jang, Byungki, Kim, Ho Won, Kim, Jong‐Seok, Kim, Woo Sik, Lee, Bo Ryeong, Kim, Sojeong, Kim, Hongmin, Han, Seung Jung, Ha, Sang‐Jun, Shin, Sung Jae

“…Peptidylarginine deiminase role in inflammatory settings viaalteration of the functional maturation of DCs. Cl‐amidine, which is a small‐molecule inhibitor of…”
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Myelin Basic Protein Citrullination, a Hallmark of Central Nervous System Demyelination, Assessed by Novel Monoclonal Antibodies in Prion Diseases by Jang, Byungki, Jeon, Yong-Chul, Shin, Hae-Young, Lee, Yun-Jung, Kim, Hyunji, Kondo, Yoshitaka, Ishigami, Akihito, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Myelin basic protein (MBP) citrullination by peptidylarginine deiminase (PAD) enzymes leads to incomplete protein-lipid bilayer interactions and vulnerability…”
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Peptidylarginine deiminase and protein citrullination in prion diseases: Strong evidence of neurodegeneration by Jang, Byungki, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I., Kim, Yong-Sun, Choi, Eun-Kyoung

“…The post-translational citrullination (deimination) process is mediated by peptidylarginine deiminases (PADs), which convert peptidylarginine into…”
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Calsenilin regulates presenilin 1/γ-secretase-mediated N-cadherin ε-cleavage and β-catenin signaling by Jang, Changhwan, Choi, Jin-Kyu, Na, Yeo-Jung, Jang, Byungki, Wasco, Wilma, Buxbaum, Joseph D, Kim, Yong-Sun, Choi, Eun-Kyoung

“…Presenilin 1 (PS1) is a component of the γ-secretase complex that cleaves a variety of type I membrane proteins, including the β-amyloid precursor protein…”
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Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination by Choi, Eun‐Kyoung, Jang, Byungki, Jeon, Yong‐Chul, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I, Kim, Yong‐Sun

“…Abstract only The citrullination of enolase by PAD (peptidylarginine deiminase) has emerged as an important post‐translational modification in human disorders;…”
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