Search Results - "Janel, N"

Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome by Fructuoso, M., Rachdi, L., Philippe, E., Denis, RG, Magnan, C., Le Stunff, H., Janel, N., Dierssen, M.

“…Down syndrome (DS) is caused by the trisomy of human chromosome 21 and is the most common genetic cause of intellectual disability. In addition to the…”
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Use of murine models for the study of obstructive sleep apnea syndrome in Down syndrome by Moreau, M, Madani, A, Dard, R, Bourgeois, T, d'Ortho, M-P, Delclaux, C, Janel, N, Matrot, B

“…Down syndrome (DS), or trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21, leading to various characteristic physical…”
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Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer’s disease by Janel, N, Alexopoulos, P, Badel, A, Lamari, F, Camproux, A C, Lagarde, J, Simon, S, Feraudet-Tarisse, C, Lamourette, P, Arbones, M, Paul, J L, Dubois, B, Potier, M C, Sarazin, M, Delabar, J M

“…Early identification of Alzheimer’s disease (AD) risk factors would aid development of interventions to delay the onset of dementia, but current biomarkers are…”
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Corrigendum to “Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome” [Free Radic. Biol. Med. 114 (2018) 122–130] by Fructuoso, M., Rachdi, L., Philippe, E., Denis, R.G., Magnan, C., Le Stunff, H., Janel, N., Dierssen, M.

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Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain by London, J., Ndiaye, F. K., Bui, L. C., Souchet, B., Daubigney, F., Magnan, C., Luquet, S., Dairou, J., Janel, N., Rouch, C.

“…Cystathionine beta synthase ( CBS ) is one of the 225 genes on chromosome 21 (HSA 21) that are triplicated in persons with trisomy 21 (Down syndrome). Although…”
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Efficient laser action of Yb:LSO and Yb:YSO oxyorthosilicates crystals under high-power diode-pumping by JACQUEMET, M, JACQUEMET, C, JANEL, N, DRUON, F, BALEMBOIS, F, GEORGES, P, PETIT, J, VIANA, B, VIVIEN, D, FERRAND, B

“…We report here on the efficient laser action of a new Yb-doped crystal Yb:Lu2SiO5 (Yb:LSO) under high power diode-pumping (15 W). Its performances were…”
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Cerebral Phospho-Tau Acts Synergistically with Soluble Aβ42 Leading to Mild Cognitive Impairment in AAV-AD Rats by Souchet, B., Audrain, M., Gu, Y., Lindberg, M. F., Orefice, N. S., Rey, E., Cartier, N., Janel, N., Meijer, L., Braudeau, Jérôme

“…Background Alzheimer’s disease (AD) is a continuum of events beginning with an increase in brain soluble Aβ342 followed by the appearance of…”
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Plasma DYRK1A as a novel risk factor for Alzheimer’s disease by Janel, N, Sarazin, M, Corlier, F, Corne, H, de Souza, L C, Hamelin, L, Aka, A, Lagarde, J, Blehaut, H, Hindié, V, Rain, J-C, Arbones, M L, Dubois, B, Potier, M C, Bottlaender, M, Delabar, J M

“…To determine whether apparent involvement of DYRK1A in Alzheimer’s disease (AD) pathology makes it a candidate plasma biomarker for diagnosis, we developed a…”
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DYRK1A as a biomarker and a therapeutic target for cognitive deficits in Down syndrome and Alzheimer’s disease by Delabar, J.M, Janel, N, Badel, A, Paul, J, Rebillat, A.S, Coskun, P, Busciglio, J, Lott, I, Schubert, M, Sarazin, M, Alexopoulos, P

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Noninvasive treatment of uterine fibroids: early Mayo Clinic experience with magnetic resonance imaging-guided focused ultrasound by Hesley, Gina K, Felmlee, Joel P, Gebhart, John B, Dunagan, Kelly T, Gorny, Krzysztof R, Kesler, Jessica B, Brandt, Kathleen R, Glantz, Janel N, Gostout, Bobbie S

“…Uterine fibroids often cause symptoms of pelvic pain, pressure, and bleeding. Traditional therapies have included medical (eg, hormonal therapy) and surgical…”
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Regulation of extracellular signal-regulated kinase by homocysteine in hippocampus by Robert, K., Pagès, C., Ledru, A., Delabar, J., Caboche, J., Janel, N.

“…In several neurological disorders including hyperhomocysteinemia, homocysteine (Hcy) accumulates in the brain, and acts as a potent neurotoxin. However, the…”
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Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat by Giroix, M-H., Irminger, J-C., Lacraz, G., Noll, C., Calderari, S., Ehses, J. A., Coulaud, J., Cornut, M., Kassis, N., Schmidlin, F., Paul, J-L., Kergoat, M., Janel, N., Halban, P. A., Homo-Delarche, F.

“…Aims/hypothesis The adult non-obese Goto–Kakizaki (GK) rat model of type 2 diabetes, particularly females, carries in addition to hyperglycaemia a genetic…”
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Homocysteine threshold value based on cystathionine beta synthase and paraoxonase 1 activities in mice by Hamelet, J., Aït-Yahya-Graison, E., Matulewicz, E., Noll, C., Badel-Chagnon, A., Camproux, A-C., Demuth, K., Paul, J-L., Delabar, J. M., Janel, N.

“…Background  Hyperhomocysteinaemia is a metabolic disorder associated with the development of premature atherosclerosis. Among the determinants which predispose…”
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O3 Un nouveau régulateur de la masse de cellule bêta : la kinase Dyrk1A by Rachdi, L, Scharfmann, R, Polak, M, Kariyawasam, D, Delabar, J, Arbones, M, Janel, N, Guez, F, Aïello, V

“…Introduction Les facteurs de croissance et les nutriments sont des régulateurs majeurs de la masse et de la fonction des cellules bêta pancréatiques. Les voies…”
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Testis-Specific Murine Centrin, Cetn1: Genomic Characterization and Evidence for Retroposition of a Gene Encoding a Centrosome Protein by Hart, Peter E., Glantz, Janel N., Orth, James D., Poynter, Gregory M., Salisbury, Jeffrey L.

“…Centrin is a centrosome component in species from yeast to humans. Here, the mouse centrin 1 gene (Cetn1) is analyzed with respect to its genomic structure,…”
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Use of Real-Time Ultrasonography to Diagnose Pseudolabor by Brink, Janel N., B.S, Emerick, Lindsay E., B.S, Caplan, Jason P., M.D, Chambliss, Linda R., M.D., M.P.H

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Silver nanoparticle array structures that produce remarkably narrow plasmon lineshapes by Zou, Shengli, Janel, Nicolas, Schatz, George C

“…Using electrodynamics calculations, we have discovered one dimensional array structures built from spherical silver nanoparticles that produce remarkably…”
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Energy specificity of rock climbing and aerobic capacity in competitive sport rock climbers by BILLAT, V, PALLEJA, P, CHARLAIX, T, RIZZARDO, P, JANEL, N

“…Over the past few years, competitive rock climbing has experienced increased popularity world wide. In 1989, the first six-event World Cup competition was held…”
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Assessment of the expression of candidate human plasma membrane phospholipid scramblase in Scott syndrome cells by Janel, N, Leroy, C, Laude, I, Toti, F, Fressinaud, E, Meyer, D, Freyssinet, J M, Kerbiriou-Nabias, D

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Characterization of the X-linked murine centrin Cetn2 gene by Hart, P E, Poynter, G M, Whitehead, C M, Orth, J D, Glantz, J N, Busby, R C, Barrett, S L, Salisbury, J L

“…A multi-gene family (Cetn1, Cetn2, and Cetn3) encodes the calcium-binding protein, centrin, in the mouse. This work characterizes the Cetn2 gene. Structurally,…”
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