Search Results - "Janecki, J."

A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme by Janecki, Dariusz J., Bemis, Kerry G., Tegeler, Tony J., Sanghani, Paresh C., Zhai, Lanmin, Hurley, Thomas D., Bosron, William F., Wang, Mu

“…Although significant progress has been made in protein quantification using mass spectrometry during recent years, absolute protein quantification in complex…”
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Basic Fibroblast Growth Factor Stimulates Surface Expression and Activity of Na+/H+ Exchanger NHE3 via Mechanism Involving Phosphatidylinositol 3-Kinase by Janecki, Andrzej J., Janecki, Maria, Akhter, Shafinaz, Donowitz, Mark

“…Na+/H+ exchanger NHE3 is a plasma membrane (PM) protein, which contributes to Na+ absorption in the intestine. Growth factors stimulate NHE3 via…”
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Use of matrix clusters and trypsin autolysis fragments as mass calibrants in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Harris, William A., Janecki, Dariusz J., Reilly, James P.

“…Trypsin autolysis fragments and matrix clusters are often observed as intense peaks in mass spectra of protein digests. It is demonstrated that these can be…”
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Membrane Association of Glutathione S-Transferase mGSTA4-4, an Enzyme That Metabolizes Lipid Peroxidation Products by Singh, Sharda P., Janecki, Andrzej J., Srivastava, Sanjay K., Awasthi, Sanjay, Awasthi, Yogesh C., Xia, Shujuan J., Zimniak, Piotr

“…Lipid peroxidation products have signaling functions and at higher concentrations are toxic and may trigger cell death. The compounds are metabolized…”
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Probing Protein Tertiary Structure with Amidination by Janecki, Dariusz J, Beardsley, Richard L, Reilly, James P

“…A chemical derivatization method, amidination, that has recently been effectively employed in peptide mass spectrometry experiments is used to covalently…”
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Quantitation of Plasma Membrane Expression of a Fusion Protein of Na/H Exchanger NHE3 and Green Fluorescence Protein (GFP) in Living PS120 Fibroblasts by Janecki, Andrzej J, Janecki, Maria, Akhter, Shafinaz, Donowitz, Mark

“…We developed a confocal morphometric analysis to quantitate the relative plasma membrane (PM) expression of the Na/H exchanger NHE3 in living PS120…”
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Denaturation of metalloproteins with EDTA to facilitate enzymatic digestion and mass fingerprinting by Janecki, Dariusz J., Reilly, James P.

“…Metal ions bound to a protein often stabilize tertiary and/or quaternary structure. Consequently, the digestion of metalloproteins that precedes analysis by…”
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Pericardoscopy for primary management of pericardial effusion in cancer patients by Porte, Henri L., Janecki-Delebecq, Thérèse J., Finzi, Laetitia, Métois, David G., Millaire, Alain, Wurtz, Alain J.

“…Objective: To assess the usefulness of pericardoscopy via the subxyphoid route for the diagnosis and treatment of pericardial effusion in patients with a…”
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Application of MALDI TOF/TOF mass spectrometry and collision-induced dissociation for the identification of disulfide-bonded peptides by Janecki, Dariusz J., Nemeth, Jennifer F.

“…This paper describes a method for the fast identification and composition of disulfide‐bonded peptides. A unique fragmentation signature of…”
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Photoimmobilization of Proteins for Affinity Capture Combined with MALDI TOF MS Analysis by Janecki, Dariusz J, Broshears, William C, Reilly, James P

“…Affinity capture surfaces can be prepared in a number of ways. A method of obtaining such surfaces through UV-activated immobilization of binding proteins…”
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Bone signal abnormalities in the posterolateral tibia and lateral femoral condyle in complete tears of the anterior cruciate ligament: a specific sign? by Murphy, B J, Smith, R L, Uribe, J W, Janecki, C J, Hechtman, K S, Mangasarian, R A

“…Thirty-two patients with acute, complete tears of the anterior cruciate ligament (ACL) proved at surgery underwent examination with magnetic resonance (MR)…”
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Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain by Almagro, Juan Carlos, Raghunathan, Gopalan, Beil, Eric, Janecki, Dariusz J., Chen, Qiang, Dinh, Thai, LaCombe, Ann, Connor, Judy, Ware, Mark, Kim, Paul H., Swanson, Ronald V., Fransson, Johan

“…Disulfide bridges are common in the antigen‐binding site from sharks (new antigen receptor) and camels (single variable heavy‐chain domain, VHH), in which they…”
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A fully integrated multi-column system for abundant protein depletion from serum/plasma by Janecki, Dariusz J., Pomerantz, Steven C, Beil, Eric J., Nemeth, Jennifer F.

“…► A conventional HPLC system set-up for automated serum/plasma depletion. ► The system uses two immunoaffinity columns in series (Seppro IgY14 and SuperMix). ►…”
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The role of interchain disulfide bond in a recombinant human interleukin-17A variant by Wu, Bingyuan, Muzammil, Salman, Jones, Brian, Nemeth, Jennifer F., Janecki, Dariusz J., Baker, Audrey, Merle Elloso, M., Naso, Michael, Carton, Jill, Taudte, Susann

“…•Refolding of a human interleukin-17A (IL-17A) variant results in covalent and non-covalent dimers.•The interchain disulfide is not essential for IL-17A…”
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A comparative proteomic study to characterize the vinblastine resistance in human ovarian cancer cells by Brown, Dawn P. G., Gökmen-Polar, Yesim, Jiang, Li, Tan, Jian, Ringham, Heather, Janecki, Dariusz J., Qi, Guihong, Witzmann, Frank A., Sledge Jr, George W., Wang, Mu

“…Drug resistance is a major impediment to the successful treatment of human cancers, including ovarian cancer. Vinblastine (VLB), an antimicrotubule agent, is…”
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Lipids in serum of patients with malignant ovarian neoplasms by Gadomska, H., Janecki, J., Marianowski, L., Nowicka, G.

“…Objective: In numerous papers, different associations of serum lipids and lipoproteins with neoplastic diseases were found. The aim of our work was to find out…”
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Why should a clinician care about the molecular biology of transport? by Janecki, A J

“…This review outlines the progress made over the last few years in three chosen areas of intestinal ion transport. In the field of intestinal secretion,…”
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Development of an endogenous epithelial Na(+)/H(+) exchanger (NHE3) in three clones of caco-2 cells by Janecki, A J, Montrose, M H, Tse, C M, de Medina, F S, Zweibaum, A, Donowitz, M

“…Expression of endogenous Na(+)/H(+) exchangers (NHEs) NHE3 and NHE1 at the apical (AP) and basolateral (BL) membrane domains was investigated in three clones…”
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Expression, refolding and purification of a human interleukin-17A variant by Wu, Bingyuan, Nemeth, Jennifer F., Janecki, Dariusz J., Jones, Brian, Obmolova, Galina, Malia, Thomas J., Baker, Audrey, Bethea, Deidra, Elloso, M. Merle, Naso, Michael, Taudte, Susann

“…A human interleukin-17A (IL-17A) variant was overexpressed in Escherichia coli BL21 (DE3) under the control of a T7 promoter. The resulting insoluble inclusion…”
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Screening for total and partial eosinoperoxidase deficiency by flow cytometry: prevalence in a general population, pathology and genetic implications by Kutter, D, Janecki, J, Verstraeten, L

“…The ADVIA (Bayer) haematological system differentiates leukocytes by their volume and their peroxidase (MPO and EPO) activity. It thus allows specific counting…”
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