Search Results - "Jandušík, Tomáš"

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases by Šimák, Ondřej, Pachl, Petr, Fábry, Milan, Buděšínský, Miloš, Jandušík, Tomáš, Hnízda, Aleš, Skleničková, Radka, Petrová, Magdalena, Veverka, Václav, Řezáčová, Pavlína, Brynda, Jiří, Rosenberg, Ivan

“…This work describes novel in vitro inhibitors of human mitochondrial (mdN) and cytosolic (cdN) 5'(3')-deoxynucleotidases. We designed a series of derivatives…”
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Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations by Novotná, Barbora, Vaneková, Lenka, Zavřel, Martin, Buděšínský, Miloš, Dejmek, Milan, Smola, Miroslav, Gutten, Ondrej, Tehrani, Zahra Aliakbar, Pimková Polidarová, Markéta, Brázdová, Andrea, Liboska, Radek, Štěpánek, Ivan, Vavřina, Zdeněk, Jandušík, Tomáš, Nencka, Radim, Rulíšek, Lubomír, Bouřa, Evžen, Brynda, Jiří, Páv, Ondřej, Birkuš, Gabriel

“…Cyclic dinucleotides are second messengers in the cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway, which plays an important role…”
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