Search Results - "Jandrey, Elisa Helena F."

Methotrexate up-regulates ecto-5′-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment by Figueiró, Fabrício, de Oliveira, Catiúscia P., Bergamin, Letícia S., Rockenbach, Liliana, Mendes, Franciane B., Jandrey, Elisa Helena F., Moritz, Cesar Eduardo J., Pettenuzzo, Letícia F., Sévigny, Jean, Guterres, Silvia S., Pohlmann, Adriana R., Battastini, Ana Maria O.

“…Glioblastoma multiforme (GBM) is a deadly cancer characterized by a pro-tumoral immune response. T-regulatory (Treg) lymphocytes suppress effector immune cells…”
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Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model by Figueiró, Fabrício, de Oliveira, Catiúscia P, Rockenbach, Liliana, Mendes, Franciane B, Bergamin, Letícia S, Jandrey, Elisa Helena F, Edelweiss, Maria Isabel, Guterres, Silvia S, Pohlmann, Adriana R, Battastini, Ana Maria O

“…Glioblastoma multiforme is a devastating cerebral tumor with an exceedingly poor prognosis. Methotrexate (MTX) is a folic acid analogue that inhibits DNA…”
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