Search Results - "Jandova, Zuzana"

Therapy of chronic hepatitis C in people who inject drugs: focus on adherence by Frankova, Sona, Jandova, Zuzana, Jinochova, Gabriela, Kreidlova, Miluse, Merta, Dusan, Sperl, Jan

“…Abstract Background Intravenous drug use (IVDU) represents the major factor of HCV transmission, but the treatment uptake among people who inject drugs (PWID)…”
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The HADDOCK2.4 web server for integrative modeling of biomolecular complexes by Honorato, Rodrigo V., Trellet, Mikael E., Jiménez-García, Brian, Schaarschmidt, Jörg J., Giulini, Marco, Reys, Victor, Koukos, Panagiotis I., Rodrigues, João P. G. L. M., Karaca, Ezgi, van Zundert, Gydo C. P., Roel-Touris, Jorge, van Noort, Charlotte W., Jandová, Zuzana, Melquiond, Adrien S. J., Bonvin, Alexandre M. J. J.

“…Interactions between macromolecules, such as proteins and nucleic acids, are essential for cellular functions. Experimental methods can fail to provide all the…”
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Native Phytoremediation Potential of Urtica dioica for Removal of PCBs and Heavy Metals Can Be Improved by Genetic Manipulations Using Constitutive CaMV 35S Promoter by Viktorova, Jitka, Jandova, Zuzana, Madlenakova, Michaela, Prouzova, Petra, Bartunek, Vilem, Vrchotova, Blanka, Lovecka, Petra, Musilova, Lucie, Macek, Tomas

“…Although stinging nettle (Urtica dioica) has been shown to reduce HM (heavy metal) content in soil, its wider phytoremediation potential has been neglected…”
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Serogroup and Clonal Characterization of Czech Invasive Neisseria meningitidis Strains Isolated from 1971 to 2015 by Jandova, Zuzana, Musilek, Martin, Vackova, Zuzana, Kozakova, Jana, Krizova, Pavla

“…This study presents antigenic and genetic characteristics of Neisseria meningitidis strains recovered from invasive meningococcal disease (IMD) in the Czech…”
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Free-Energy Calculations for Bioisosteric Modifications of A3 Adenosine Receptor Antagonists by Jandova, Zuzana, Jespers, Willem, Sotelo, Eddy, Gutiérrez-de-Terán, Hugo, Oostenbrink, Chris

“…Adenosine receptors are a family of G protein-coupled receptors with increased attention as drug targets on different indications. We investigate the…”
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Correction: Native Phytoremediation Potential of Urtica dioica for Removal of PCBs and Heavy Metals Can Be Improved by Genetic Manipulations Using Constitutive CaMV 35S Promoter by Viktorova, Jitka, Jandova, Zuzana, Madlenakova, Michaela, Prouzova, Petra, Bartunek, Vilem, Vrchotova, Blanka, Lovecka, Petra, Musilova, Lucie, Macek, Tomas

“…[This corrects the article DOI: 10.1371/journal.pone.0167927.]…”
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‘Click chemistry’ synthesis of 1-(α-d-mannopyranosyl)-1,2,3-triazoles for inhibition of α-mannosidases by Poláková, Monika, Stanton, Rhiannon, Wilson, Iain B.H., Holková, Ivana, Šesták, Sergej, Machová, Eva, Jandová, Zuzana, Kóňa, Juraj

“…Three new triazole conjugates derived from d-mannose were synthesized and assayed in in vitro assays to investigate their ability to inhibit α-mannosidase…”
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Saturation Mutagenesis by Efficient Free-Energy Calculation by Jandova, Zuzana, Fast, Daniel, Setz, Martina, Pechlaner, Maria, Oostenbrink, Chris

“…Single-point mutations in proteins can greatly influence protein stability, binding affinity, protein function or its expression per se. Here, we present…”
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Native or Non-Native Protein–Protein Docking Models? Molecular Dynamics to the Rescue by Jandova, Zuzana, Vargiu, Attilio Vittorio, Bonvin, Alexandre M. J. J

“…Molecular docking excels at creating a plethora of potential models of protein–protein complexes. To correctly distinguish the favorable, native-like models…”
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Binding Modes and Metabolism of Caffeine by Jandova, Zuzana, Gill, Samuel C, Lim, Nathan M, Mobley, David L, Oostenbrink, Chris

“…A correct estimate of ligand binding modes and a ratio of their occupancies is crucial for calculations of binding free energies. The newly developed method…”
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Free energy calculations on the stability of the 14-3-3ζ protein by Jandova, Zuzana, Trosanova, Zuzana, Weisova, Veronika, Oostenbrink, Chris, Hritz, Jozef

“…Mutations of cysteine are often introduced to e.g. avoid formation of non-physiological inter-molecular disulfide bridges in in-vitro experiments, or to…”
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Free-Energy Calculations for Bioisosteric Modifications of A(3) Adenosine Receptor Antagonists by Jandova, Zuzana, Jespers, Willem, Sotelo, Eddy, Gutiérrez-de-Terán, Hugo, Oostenbrink, Chris

“…Adenosine receptors are a family of G protein-coupled receptors with increased attention as drug targets on different indications. We investigate the…”
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Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b by Milazzo, Lisa, Gabler, Thomas, Pühringer, Dominic, Jandova, Zuzana, Maresch, Daniel, Michlits, Hanna, Pfanzagl, Vera, Djinović-Carugo, Kristina, Oostenbrink, Chris, Furtmüller, Paul G, Obinger, Christian, Smulevich, Giulietta, Hofbauer, Stefan

“…Coproheme decarboxylase (ChdC) catalyzes the last step in the heme biosynthesis pathway of monoderm bacteria with coproheme acting both as redox cofactor and…”
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Chemistry and Molecular Dynamics Simulations of Heme b‑HemQ and Coproheme-HemQ by Hofbauer, Stefan, Dalla Sega, Marco, Scheiblbrandner, Stefan, Jandova, Zuzana, Schaffner, Irene, Mlynek, Georg, Djinović-Carugo, Kristina, Battistuzzi, Gianantonio, Furtmüller, Paul G, Oostenbrink, Chris, Obinger, Christian

“…Recently, a novel pathway for heme b biosynthesis in Gram-positive bacteria has been proposed. The final poorly understood step is catalyzed by an enzyme…”
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Abstract B037: Hit-finding by Cysteine-Scanning (HCS): A method for finding druggable pockets by van Tienen, Laurens Moore, Bayoumi, Shadwa, Muneeruddin, Khaja, Leymarie, Nancy, Kornfilt, David, Bian, Yuemin, Kesar, Devishi, Li, Ruitong, Atack, Thomas, Popa, Alexandra-Mariela, Jandova, Zuzana, Trollmann, Philipp, Bergner, Andreas, Rumpel, Klaus, Kessler, Dirk, Sellers, William R.

“…Abstract Large-scale cancer sequencing efforts coupled with deep functional genomic interrogation of cancer models provides us an increasingly detailed view of…”
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Free-Energy Calculations for Bioisosteric Modifications of A 3 Adenosine Receptor Antagonists by Jandova, Zuzana, Jespers, Willem, Sotelo, Eddy, Gutiérrez-de-Terán, Hugo, Oostenbrink, Chris

“…Adenosine receptors are a family of G protein-coupled receptors with increased attention as drug targets on different indications. We investigate the…”
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A protocol for information-driven antibody-antigen modelling with the HADDOCK2.4 webserver by Ambrosetti, Francesco, Jandova, Zuzana, Bonvin, Alexandre M. J. J

“…In the recent years, therapeutic use of antibodies has seen a huge growth, due to their inherent proprieties and technological advances in the methods used to…”
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