Search Results - "Janczy, John R"

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation by Iyer, Shankar S., He, Qiong, Janczy, John R., Elliott, Eric I., Zhong, Zhenyu, Olivier, Alicia K., Sadler, Jeffrey J., Knepper-Adrian, Vickie, Han, Renzhi, Qiao, Liang, Eisenbarth, Stephanie C., Nauseef, William M., Cassel, Suzanne L., Sutterwala, Fayyaz S.

“…Nlrp3 inflammasome activation occurs in response to numerous agonists but the specific mechanism by which this takes place remains unclear. All previously…”
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Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice by Cassel, Suzanne L., Janczy, John R., Bing, Xinyu, Wilson, Shruti P., Olivier, Alicia K., Otero, Jesse E., lwakura, Yoichiro, Shayakhmetov, Dmitry M., Bassuk, Alexander G., Abu-Amer, Yousef, Brogden, Kim A., Burns, Trudy L., Sutterwala, Fayyaz S., Ferguson, Polly J.

“…Chronic recurrent multifocal osteomyelitis (CRMO) is a human autoinflammatory disorder that primarily affects bone. Missense mutation (L98P) of…”
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Control of innate and adaptive immunity by the inflammasome by Ciraci, Ceren, Janczy, John R., Sutterwala, Fayyaz S., Cassel, Suzanne L.

“…The importance of innate immunity lies not only in directly confronting pathogenic and non-pathogenic insults but also in instructing the development of an…”
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Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome by KUIPERS, Maria T, ASLAMI, Hamid, BRESSER, Paul, LEEMANS, Jaklien C, DER POLL, Tom Van, SCHULTZ, Marcus J, WIELAND, Catharina W, JANCZY, John R, DER SLUIJS, Koenraad F. Van, VLAAR, Alexander P. J, WOLTHUIS, Esther K, CHOI, Goda, ROELOFS, Joris J. T. H, FLAVELL, Richard A, SUTTERWALA, Fayyaz S

“…The innate immune response is important in ventilator-induced lung injury (VILI) but the exact pathways involved are not elucidated. The authors studied the…”
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Immune complexes inhibit IL-1 secretion and inflammasome activation by Janczy, John R, Ciraci, Ceren, Haasken, Stefanie, Iwakura, Yoichiro, Olivier, Alicia K, Cassel, Suzanne L, Sutterwala, Fayyaz S

“…IgG immune complexes have been shown to modify immune responses driven by APCs in either a pro- or anti-inflammatory direction depending upon the context of…”
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Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo by Ciraci, Ceren, Janczy, John R, Jain, Nidhi, Haasken, Stefanie, Pecli E Silva, Cyntia, Benjamim, Claudia F, Sadler, Jeffrey J, Olivier, Alicia K, Iwakura, Yoichiro, Shayakhmetov, Dmitry M, Sutterwala, Fayyaz S, Cassel, Suzanne L

“…The precise context in which the innate immune system is activated plays a pivotal role in the subsequent instruction of CD4+ T helper (Th) cell responses. Th1…”
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Thermal Stabilization of Biologics with Photoresponsive Hydrogels by Sridhar, Balaji V, Janczy, John R, Hatlevik, Øyvind, Wolfson, Gabriel, Anseth, Kristi S, Tibbitt, Mark W

“…Modern medicine, biological research, and clinical diagnostics depend on the reliable supply and storage of complex biomolecules. However, biomolecules are…”
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Thermal stabilization of diverse biologics using reversible hydrogels by Marco-Dufort, Bruno, Janczy, John R, Hu, Tianjing, Lütolf, Marco, Gatti, Francesco, Wolf, Morris, Woods, Alex, Tetter, Stephan, Sridhar, Balaji V, Tibbitt, Mark W

“…Improving the thermal stability of biologics, including vaccines, is critical to reduce the economic costs and health risks associated with the cold chain…”
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Immune complexes inhibit interleukin-1 secretion and inflammasome activation by Janczy, John R., Ciraci, Ceren, Haasken, Stefanie, Iwakura, Yoichiro, Olivier, Alicia K., Cassel, Suzanne L., Sutterwala, Fayyaz S.

“…Immunoglobulin G (IgG) immune complexes have been shown to modify immune responses driven by antigen presenting cells in either a pro- or anti-inflammatory…”
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Control of innate and adaptive immunity by the inflammasome : Danger signals and immunity by CIRACI, Ceren, JANCZY, John R, SUTTERWALA, Fayyaz S, CASSEL, Suzanne L

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Inflammasome-independent IL-1[Beta] mediates autoinflammatory disease in Pstpip2-deficient mice by Cassel, Suzanne L, Janczy, John R, Bing, Xinyu, Wilson, Shruti P, Olivier, Alicia K, Otero, Jesse E, Iwakura, Yoichiro, Shayakhmetov, Dmitry M, Bassuk, Alexander G, Abu-Amer, Yousef, Brogden, Kim A, Burns, Trudy L, Sutterwala, Fayyaz S, Ferguson, Polly J

“…Chronic recurrent multifocal osteomyelitis (CRMO) is a human autoinflammatory disorder that primarily affects bone. Missense mutation (L98P) of…”
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Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo: e0151252 by Ciraci, Ceren, Janczy, John R, Jain, Nidhi, Haasken, Stefanie, Silva, Cyntia Peclie, Benjamim, Claudia F, Sadler, Jeffrey J, Olivier, Alicia K, Iwakura, Yoichiro, Shayakhmetov, Dmitry M

“…The precise context in which the innate immune system is activated plays a pivotal role in the subsequent instruction of CD4+ T helper (Th) cell responses. Th1…”
Get full text