Search Results - "Janczura, J."

miR‐184 regulates ezrin, LAMP‐1 expression, affects phagocytosis in human retinal pigment epithelium and is downregulated in age‐related macular degeneration by Murad, Najiba, Kokkinaki, Maria, Gunawardena, Nishantha, Gunawan, Mia S, Hathout, Yetrib, Janczura, Karolina J, Theos, Alexander C, Golestaneh, Nady

“…MicroRNA 184 (miR‐184) is known to play a key role in neurological development and apoptosis and is highly expressed in mouse brain, mouse corneal epithelium,…”
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Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family by Neale, Joseph H., Olszewski, Rafal T., Zuo, Daiying, Janczura, Karolina J., Profaci, Caterina P., Lavin, Kaleen M., Madore, John C., Bzdega, Tomasz

“…J. Neurochem. (2011) 118, 490–498. A substantial body of data was reported between 1984 and 2000 demonstrating that the neuropeptide N‐acetylaspartylglutamate…”
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Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model by Janczura, Karolina J., Volmar, Claude-Henry, Sartor, Gregory C., Rao, Sunil J., Ricciardi, Natalie R., Lambert, Guerline, Brothers, Shaun P., Wahlestedt, Claes

“…Alzheimer’s disease (AD) is the leading cause of age-related dementia. Neuropathological hallmarks of AD include brain deposition of β-amyloid (Aβ) plaques and…”
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NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia by Olszewski, R T, Janczura, K J, Ball, S R, Madore, J C, Lavin, K M, Lee, J C-M, Lee, M J, Der, E K, Hark, T J, Farago, P R, Profaci, C P, Bzdega, T, Neale, J H

“…The most widely validated animal models of the positive, negative and cognitive symptoms of schizophrenia involve administration of d -amphetamine or the open…”
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RETRACTED: Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model by Janczura, Karolina J., Volmar, Claude-Henry, Sartor, Gregory C., Rao, Sunil J., Ricciardi, Natalie R., Lambert, Guerline, Brothers, Shaun P., Wahlestedt, Claes

“…Alzheimer’s disease (AD) is the leading cause of age-related dementia. Neuropathological hallmarks of AD include brain deposition of β-amyloid (Aβ) plaques and…”
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Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins by Sartor, Gregory C, Malvezzi, Andrea M, Kumar, Ashok, Andrade, Nadja S, Wiedner, Hannah J, Vilca, Samantha J, Janczura, Karolina J, Bagheri, Amir, Al-Ali, Hassan, Powell, Samuel K, Brown, Peyton T, Volmar, Claude H, Foster, Thomas C, Zeier, Zane, Wahlestedt, Claes

“…Histone deacetylase (HDAC) inhibitors may have therapeutic utility in multiple neurological and psychiatric disorders, but the underlying mechanisms remain…”
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M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer’s disease genes and improving memory by Volmar, Claude-Henry, Salah-Uddin, Hasib, Janczura, Karolina J., Halley, Paul, Lambert, Guerline, Wodrich, Andrew, Manoah, Sivan, Patel, Nidhi H., Sartor, Gregory C., Mehta, Neil, Miles, Nancy T. H., Desse, Sachi, Dorcius, David, Cameron, Michael D., Brothers, Shaun P., Wahlestedt, Claes

“…Alzheimer’s disease (AD) comprises multifactorial ailments for which current therapeutic strategies remain insufficient to broadly address the underlying…”
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Characterization and biodistribution of under-employed gene therapy vector AAV7 by Yost, Samantha A., Firlar, Emre, Glenn, Justin D., Carroll, Hayley B., Foltz, Steven, Giles, April R., Egley, Jenny M., Firnberg, Elad, Cho, Sungyeon, Nguyen, Trang, Henry, William M., Janczura, Karolina J., Bruder, Joseph, Liu, Ye, Danos, Olivier, Karumuthil-Melethil, Subha, Pannem, Sanjana, Yost, Valerie, Engelson, Yelena, Kaelber, Jason T., Dimant, Hemi, Smith, Jared B., Mercer, Andrew C.

“…ABSTRACT AAV7 is a clade D adeno-associated virus (AAV) whose potential as a gene therapy vector has not been fully evaluated. We show here that high-titer…”
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Longevity‐related molecular pathways are subject to midlife “switch” in humans by Timmons, James A., Volmar, Claude‐Henry, Crossland, Hannah, Phillips, Bethan E., Sood, Sanjana, Janczura, Karolina J., Törmäkangas, Timo, Kujala, Urho M., Kraus, William E., Atherton, Philip J., Wahlestedt, Claes

“…Emerging evidence indicates that molecular aging may follow nonlinear or discontinuous trajectories. Whether this occurs in human neuromuscular tissue,…”
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Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue by Janczura, Karolina J, Volmar, Claude-Henry, Wahlestedt, Claes

“…In all eukaryotic organisms, chromatin, the physiological template of all genetic information, is essential for heredity. Chromatin is subject to an array of…”
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NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer’s, and Ethanol Intoxication by Olszewski, Rafal T., Janczura, Karolina J., Bzdega, Tomasz, Der, Elise K., Venzor, Faustino, O’Rourke, Brennen, Hark, Timothy J., Craddock, Kirsten E., Balasubramanian, Shankar, Moussa, Charbel, Neale, Joseph H.

“…Glutamate carboxypeptidase II (GCPII) inactivates the peptide neurotransmitter N -acetylaspartylglutamate (NAAG) following synaptic release. Inhibitors of…”
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An empirical comparison of alternate regime-switching models for electricity spot prices by Janczura, Joanna, Weron, Rafal

“…One of the most profound features of electricity spot prices are the price spikes. Markov regime-switching (MRS) models seem to be a natural candidate for…”
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Black swans or dragon-kings? A simple test for deviations from the power law by Janczura, J., Weron, R.

“…We develop a simple test for deviations from power law tails. Actually, from the tails of any distribution. We use this test – which is based on the asymptotic…”
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NAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test by Janczura, Karolina J., Olszewski, Rafal T., Bzdega, Tomasz, Bacich, Dean J., Heston, Warren D., Neale, Joseph H.

“…The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) is inactivated by the extracellular enzyme glutamate carboxypeptidase II. Inhibitors of this…”
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The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB by Theos, Alexander C., Watt, Brenda, Harper, Dawn C., Janczura, Karolina J., Theos, Sarah C., Herman, Kathryn E., Marks, Michael S.

“…Summary Proteolytic fragments of the pigment cell‐specific glycoprotein, PMEL, form the amyloid fibrillar matrix underlying melanins in melanosomes. The…”
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Prediction performance of Hidden Markov modelling for solar flares by Stanislavsky, A., Nitka, W., Małek, M., Burnecki, K., Janczura, J.

“…Solar flares are large explosions in the sun’s atmosphere. They can damage satellites and overload electrical systems. To manage that risk, finding methods of…”
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Black swans or dragon-kings? A simple test for deviations from the power law: Discussion and Debate: From Black Swans to Dragon-Kings - Is There Life Beyond Power Laws ? by JANCZURA, J, WERON, R

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A New Method For Automated Noise Cancellation In Electromagnetic Field Measurement by Bieńkowski, P., Burnecki, K., Janczura, J., Weron, R., Zubrzak, B.

“…Electromagnetic field (EMF) measurements have limited accuracy, which is additionally impaired by meter self-noise influence. In this paper, a novel noise…”
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Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue by Janczura, Karolina J., Volmar, Claude-Henry, Wahlestedt, Claes

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Benefits of a novel highly bioavailable resveratrol formulation, JOTROL, for Alzheimer’s disease: Nonhuman/Lead optimization studies by Volmar, Claude‐Henry, Dennison, Jessica, Ricciardi, Natalie R., Janczura, Karolina J., Walker, Brittni R., Brown, Jonathan M., Stahl, Jack, Hayward, Marshall A., Brothers, Shaun P., Wahlestedt, Claes

“…Abstract Background With the recent Alzheimer’s disease (AD) clinical trial shortcomings, we and colleagues agree that an epigenetic approach is needed to…”
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