Refractive Error and Ocular Biometric Changes in the Treatment of Diabetes Mellitus
Background and Objectives: Evaluation of changes in refractive errors and biometric parameters in the process of glycemic control in people with type 2 diabetes during three-month treatment. Methods: Patients with the first diagnosis of type 2 diabetes or a history of poor glycemic control (hemoglob...
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| Published in: | Function and disability journal Vol. 5; no. 1; p. 60 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Iran University of Medical Sciences
25-06-2023
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Background and Objectives: Evaluation of changes in refractive errors and biometric parameters in the process of glycemic control in people with type 2 diabetes during three-month treatment. Methods: Patients with the first diagnosis of type 2 diabetes or a history of poor glycemic control (hemoglobin glycate more than 7.5%) and without any systemic disease other than diabetes were included. Hemoglobin glycate, refractive error, and biometric parameters were evaluated before treatment and one and a half and three months after treatment, and their changes were examined by generalized estimating equation (GEE) analysis. Results: A total of 60 eyes of 30 patients with a mean age of 51.63±6.79 years were evaluated. Hemoglobin glycate decreased by an average of 1.028% compared to the baseline measurement in the third month (P<0.001). Mean spherical (P=0.554), spherical equivalent (P=0.340), axial length (P=0.147), and anterior chamber depth (P=0.336) did not show a significant difference between the three examinations. In contrast, the lens thickness showed a significant decrease during treatment (P=0.001). Finally, generalized estimating equation (GEE) analysis showed that a 1% decrease in hemoglobin glycate increased by 0.226 mm. (P=0.002) in the axial length. It should be mentioned in tables FU1means Follow-up 1.5 months and FU2 means Follow-up 3 months. Conclusion: The present study shows that refractive errors and most ocular biometric parameters do not change significantly compared to the baseline levels in the period of one and a half and three months after the start of glycemic control. |
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| ISSN: | 2588-6304 2588-6304 |
| DOI: | 10.32598/fdj.5.60 |