Search Results - "Janakaloti Narayanareddy, Babu Reddy"
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A new method to experimentally quantify dynamics of initial protein–protein interactions
Published in Communications biology (12-03-2024)“…Cells run on initiation of protein-protein interactions, which are dynamically tuned spatially and temporally to modulate cellular events. This tuning can be…”
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Diffusion of kinesin motors on cargo can enhance binding and run lengths during intracellular transport
Published in Molecular biology of the cell (19-04-2021)“…Cellular cargoes, including lipid droplets and mitochondria, are transported along microtubules using molecular motors such as kinesins. Many experimental and…”
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Competition between physical search and a weak-to-strong transition rate-limits kinesin binding times
Published in PLoS computational biology (01-05-2024)“…The self-organization of cells relies on the profound complexity of protein-protein interactions. Challenges in directly observing these events have hindered…”
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Microtubule C‐Terminal Tails Can Change Characteristics of Motor Force Production
Published in Traffic (Copenhagen, Denmark) (01-10-2015)“…Control of intracellular transport is poorly understood, and functional ramifications of tubulin isoform differences between cell types are mostly unexplored…”
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A Biophysical Analysis of Mitochondrial Movement: Differences Between Transport in Neuronal Cell Bodies Versus Processes
Published in Traffic (Copenhagen, Denmark) (01-07-2014)“…There is an increasing interest in factors that can impede cargo transport by molecular motors inside the cell. Although potentially relevant (Yi JY,…”
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The microtubule associated protein 4 (MAP4) sweeps organelles towards the nucleus by weakening the kinesin motor
Published in Biophysical journal (10-02-2023)Get full text
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Cargo Binding to Microtubules
Published in Biophysical journal (12-02-2021)Get full text
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Molecular Mechanisms of Dynein Force Persistence in Lipid Droplet Transport
Published in Biophysical journal (02-02-2018)Get full text
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Dynamic Force Adaptation of Lipid Droplets in Sub-Cellular Transport
Published in Biophysical journal (28-01-2014)Get full text
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Dynamic Force Adaptation of Lipid Droplets during Intracellular Transport in Cos1 Cells
Published in Biophysical journal (29-01-2013)Get full text
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