Search Results - "Janaka, Sanath Kumar"

Sequences in Gibbon Ape Leukemia Virus Envelope That Confer Sensitivity to HIV-1 Accessory Protein Vpu by KUMAR JANAKA, Sanath, LUCAS, Tiffany M, JOHNSON, Marc C

“…Author's Correction ( vol. 87 , p. 7198 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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A SNP of lncRNA gives HIV-1 a boost by Janaka, Sanath Kumar, Evans, David T.

“…Although the molecular basis of most disease-associated single-nucleotide polymorphisms has remained elusive, an HIV-1 viral load–associated polymorphism…”
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Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells by Snow, Brian J, Keles, Nida K, Grunst, Michael W, Janaka, Sanath Kumar, Behrens, Ryan T, Evans, David T

“…Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the…”
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Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not enhance viral infection by Clark, Natasha M, Janaka, Sanath Kumar, Hartman, William, Stramer, Susan, Goodhue, Erin, Weiss, John, Evans, David T, Connor, Joseph P

“…The novel coronavirus, SARS-CoV-2 that causes COVID-19 has resulted in the death of nearly 4 million people within the last 18 months. While preventive…”
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Predicting the efficacy of COVID-19 convalescent plasma donor units with the Lumit Dx anti-receptor binding domain assay by Janaka, Sanath Kumar, Clark, Natasha M, Evans, David T, Mou, Huihui, Farzan, Michael, Connor, Joseph P

“…Background The novel coronavirus SARS-CoV2 that causes COVID-19 has resulted in the death of more than 2.5 million people, but no cure exists. Although passive…”
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Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques by Tavakoli-Tameh, Aidin, Janaka, Sanath Kumar, Zarbock, Katie, O'Connor, Shelby, Crosno, Kristin, Capuano, 3rd, Saverio, Uno, Hajime, Lifson, Jeffrey D, Evans, David T

“…Most simian immunodeficiency viruses use Nef to counteract the tetherin proteins of their nonhuman primate hosts. Nef also downmodulates cell-surface CD4 and…”
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The Antiviral Factor SERINC5 Impairs the Expression of Non-Self-DNA by Shi, Yuhang, Simpson, Sydney, Ahmed, Shahad K, Chen, Yuexuan, Tavakoli-Tameh, Aidin, Janaka, Sanath Kumar, Evans, David T, Serra-Moreno, Ruth

“…SERINC5 is a restriction factor that becomes incorporated into nascent retroviral particles, impairing their ability to infect target cells. In turn,…”
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Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge by Grunst, Michael W, Gil, Hwi Min, Grandea, 3rd, Andres G, Snow, Brian J, Andrabi, Raiees, Nedellec, Rebecca, Burton, Iszac, Clark, Natasha M, Janaka, Sanath Kumar, Keles, Nida K, Moriarty, Ryan V, Weiler, Andrea M, Capuano, 3rd, Saverio, Fennessey, Christine M, Friedrich, Thomas C, O'Connor, Shelby L, O'Connor, David H, Broman, Aimee T, Keele, Brandon F, Lifson, Jeffrey D, Hangartner, Lars, Burton, Dennis R, Evans, David T

“…Fc-mediated antibody effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), can contribute to the containment HIV-1 replication but…”
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KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success by Nicholas, Rachel E, Sandstrom, Kjell, Anderson, Jennifer L, Smith, Willow R, Wetzel, Molly, Banerjee, Priyankana, Janaka, Sanath Kumar, Evans, David T

“…Knowledge of the MHC class I ligands of rhesus macaque killer-cell Ig-like receptors (KIRs) is fundamental to understanding the role of natural killer (NK)…”
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Retrovirus Glycoprotein Functionality Requires Proper Alignment of the Ectodomain and the Membrane-Proximal Cytoplasmic Tail by Janaka, Sanath Kumar, Gregory, Devon A, Johnson, Marc C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Functional complementation of a model target to study Vpu sensitivity by Janaka, Sanath Kumar, Faurot, Jared, Johnson, Marc C

“…HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have…”
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Selective Disruption of SERINC5 Antagonism by Nef Impairs Simian Immunodeficiency Virus Replication in Primary CD4+ T Cells by Janaka, Sanath Kumar, Palumbo, Alexandra V, Tavakoli-Tameh, Aidin, Evans, David T

“…The Nef proteins of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) enhance viral infectivity by preventing the…”
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Substitutions in Nef That Uncouple Tetherin and SERINC5 Antagonism Impair Simian Immunodeficiency Virus Replication in Primary Rhesus Macaque Lymphocytes by Janaka, Sanath Kumar, Snow, Brian J, Behrens, Ryan T, Evans, David T

“…Most simian immunodeficiency viruses (SIVs) use Nef to counteract restriction by the tetherin proteins of their nonhuman primate hosts. In addition to…”
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Sequence Determinants in Gammaretroviral Env Cytoplasmic Tails Dictate Virus-Specific Pseudotyping Compatibility by Song, Yul Eum, Olinger, Grace Y, Janaka, Sanath Kumar, Johnson, Marc C

“…Viruses can incorporate foreign glycoproteins to form infectious particles through a process known as pseudotyping. However, not all glycoproteins are…”
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Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses by Grunst, Michael W, Grandea, 3rd, Andres G, Janaka, Sanath Kumar, Hammad, Iman, Grimes, Parker, Karl, Julie A, Wiseman, Roger, O'Connor, David H, Evans, David T

“…The rhesus macaque is an important animal model for AIDS and other infectious diseases. However, the investigation of Fc-mediated Ab responses in macaques is…”
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Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal-Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus Macaque by Banerjee, Priyankana, Ries, Moritz, Janaka, Sanath Kumar, Grandea, 3rd, Andres G, Wiseman, Roger, O'Connor, David H, Golos, Thaddeus G, Evans, David T

“…The rhesus macaque is an important animal model for AIDS and other infectious diseases; however, studies to address NK cell function in this species have been…”
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Sequences in Gibbon Ape Leukemia Virus Envelope That Confer Sensitivity to HIV-1 Accessory Protein Vpu by Janaka, Sanath Kumar, Lucas, Tiffany M., Johnson, Marc C.

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Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses by Schouest, Blake, Weiler, Andrea M, Janaka, Sanath Kumar, Myers, Tereance A, Das, Arpita, Wilder, Sarah C, Furlott, Jessica, Baddoo, Melody, Flemington, Erik K, Rakasz, Eva G, Evans, David T, Friedrich, Thomas C, Maness, Nicholas J

“…Nef-specific CD8 T lymphocytes (CD8TL) are linked to extraordinary control of primate lentiviral replication, but the mechanisms underlying their efficacy…”
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Selective Disruption of SERINC5 Antagonism by Nef Impairs SIV Replication in Primary CD4 + T Cells by Janaka, Sanath Kumar, Palumbo, Alexandra V, Tavakoli-Tameh, Aidin, Evans, David T

“…The Nef proteins of HIV-1 and SIV enhance viral infectivity by preventing the incorporation of the multipass transmembrane protein serine incorporator 5…”
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Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in Acute Viremia in Simian Immunodeficiency Virus Δ nef -Infected Animals by Janaka, Sanath Kumar, Tavakoli-Tameh, Aidin, Neidermyer, Jr, William J, Serra-Moreno, Ruth, Hoxie, James A, Desrosiers, Ronald C, Johnson, R Paul, Lifson, Jeffrey D, Wolinsky, Steven M, Evans, David T

“…Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein that inhibits virus release from infected cells. To determine the extent of sequence…”
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