Search Results - "Janáky, Tamás"

Clinical relevance of depressed kynurenine pathway in episodic migraine patients: potential prognostic markers in the peripheral plasma during the interictal period by Tuka, Bernadett, Nyári, Aliz, Cseh, Edina Katalin, Körtési, Tamás, Veréb, Dániel, Tömösi, Ferenc, Kecskeméti, Gábor, Janáky, Tamás, Tajti, János, Vécsei, László

“…Background Altered glutamatergic neurotransmission and neuropeptide levels play a central role in migraine pathomechanism. Previously, we confirmed that…”
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Sources of Variance in Human Tear Proteomic Samples: Statistical Evaluation, Quality Control, Normalization, and Biological Insight by Bruszel, Bella, Tóth-Molnár, Edit, Janáky, Tamás, Szabó, Zoltán

“…Human tear fluid contains numerous compounds, which are present in highly variable amounts owing to the dynamic and multipurpose functions of tears. A better…”
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An Extensive Study of Phenol Red Thread as a Novel Non-Invasive Tear Sampling Technique for Proteomics Studies: Comparison with Two Commonly Used Methods by Kecskeméti, Gábor, Tóth-Molnár, Edit, Janáky, Tamás, Szabó, Zoltán

“…Tear samples are considered in recent publications as easily, noninvasively collectible information sources for precision medicine. Their complex composition…”
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Nasal delivery of nanosuspension-based mucoadhesive formulation with improved bioavailability of loratadine: Preparation, characterization, and in vivo evaluation by Alshweiat, Areen, Csóka, IIdikó, Tömösi, Ferenc, Janáky, Tamás, Kovács, Anita, Gáspár, Róbert, Sztojkov-Ivanov, Anita, Ducza, Eszter, Márki, Árpád, Szabó-Révész, Piroska, Ambrus, Rita

“…[Display omitted] The unique requirements of poorly water-soluble drug delivery have driven a great deal of research into new formulations and routes of…”
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A validated UHPLC-MS method for tryptophan metabolites: Application in the diagnosis of multiple sclerosis by Tömösi, Ferenc, Kecskeméti, Gábor, Cseh, Edina Katalin, Szabó, Elza, Rajda, Cecília, Kormány, Róbert, Szabó, Zoltán, Vécsei, László, Janáky, Tamás

“…[Display omitted] •Simultaneous and robust quantification of tryptophan and its 11 metabolites.•Derivatization; separation of analytes on pentafluorophenyl…”
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Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats by Váczi, Sándor, Barna, Lilla, Laczi, Krisztián, Tömösi, Ferenc, Rákhely, Gábor, Penke, Botond, Fülöp, Lívia, Bogár, Ferenc, Janáky, Tamás, Deli, Mária A, Mezei, Zsófia

“…Diabetes mellitus is a chronic metabolic disorder which induces endothelial dysfunction and platelet activation. Eicosanoids produced from arachidonic acid…”
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Cluster headache and kynurenines by Tuka, Bernadett, Körtési, Tamás, Nánási, Nikolett, Tömösi, Ferenc, Janáky, Tamás, Veréb, Dániel, Szok, Délia, Tajti, János, Vécsei, László

“…Background The glutamatergic neurotransmission has important role in the pathomechanism of primary headache disorders. The kynurenine metabolites derived from…”
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Heart-cutting two-dimensional liquid chromatography coupled to quadrupole-orbitrap high resolution mass spectrometry for determination of N,N-dimethyltryptamine in rat plasma and brain; Method development and application by Körmöczi, Tímea, Szabó, Írisz, Farkas, Eszter, Penke, Botond, Janáky, Tamás, Ilisz, István, Berkecz, Róbert

“…•Development of 2D-LC-HRMS/MS for determination of N,N-dimethyltryptamine (DMT) in rat plasma and brain.•New sample preparation procedure of DMT with detailed…”
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Comprehensive phospholipid and sphingomyelin profiling of different brain regions in mouse model of anxiety disorder using online two-dimensional (HILIC/RP)-LC/MS method by Berkecz, Róbert, Tömösi, Ferenc, Körmöczi, Tímea, Szegedi, Viktor, Horváth, János, Janáky, Tamás

“…•Development of novel online 2D-LC/MS method for comprehensive analysis of phospholipids and sphingomyelins in brain sample.•Profiling of PL and SM composition…”
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Inhibition of ABCG2/BCRP-mediated transport–correlation analysis of various expression systems and probe substrates by Sáfár, Zsolt, Kecskeméti, Gábor, Molnár, Judit, Kurunczi, Anita, Szabó, Zoltán, Janáky, Tamás, Kis, Emese, Krajcsi, Péter

“…BCRP / ABCG2 is a key determinant of pharmacokinetics of substrate drugs. Several BCRP substrates and inhibitors are of low passive permeability, and the…”
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Soluplus® promotes efficient transport of meloxicam to the central nervous system via nasal administration by Sipos, Bence, Bella, Zsolt, Gróf, Ilona, Veszelka, Szilvia, Deli, Mária A., Szűcs, Kálmán F., Sztojkov-Ivanov, Anita, Ducza, Eszter, Gáspár, Róbert, Kecskeméti, Gábor, Janáky, Tamás, Volk, Balázs, Budai-Szűcs, Mária, Ambrus, Rita, Szabó-Révész, Piroska, Csóka, Ildikó, Katona, Gábor

“…[Display omitted] •Meloxicam-loaded micelles provided efficient cellular permeability.•The micelle formulation is applicable for the nasal…”
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Investigation of Absorption Routes of Meloxicam and Its Salt Form from Intranasal Delivery Systems by Bartos, Csilla, Ambrus, Rita, Kovács, Anita, Gáspár, Róbert, Sztojkov-Ivanov, Anita, Márki, Árpád, Janáky, Tamás, Tömösi, Ferenc, Kecskeméti, Gábor, Szabó-Révész, Piroska

“…The aim of this article was to study the trans-epithelial absorption to reach the blood and to target the brain by axonal transport using nasal formulations…”
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Preparation and characterization of lamotrigine containing nanocapsules for nasal administration by Gieszinger, Péter, Stefania Csaba, Noemi, Garcia-Fuentes, Marcos, Prasanna, Maruthi, Gáspár, Róbert, Sztojkov-Ivanov, Anita, Ducza, Eszter, Márki, Árpád, Janáky, Tamás, Kecskeméti, Gábor, Katona, Gábor, Szabó-Révész, Piroska, Ambrus, Rita

“…[Display omitted] Nanocapsules (NCs) have become one of the most researched nanostructured drug delivery systems due to their advantageous properties and…”
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Development of Meloxicam-Human Serum Albumin Nanoparticles for Nose-to-Brain Delivery via Application of a Quality by Design Approach by Katona, Gábor, Balogh, György Tibor, Dargó, Gergő, Gáspár, Róbert, Márki, Árpád, Ducza, Eszter, Sztojkov-Ivanov, Anita, Tömösi, Ferenc, Kecskeméti, Gábor, Janáky, Tamás, Kiss, Tamás, Ambrus, Rita, Pallagi, Edina, Szabó-Révész, Piroska, Csóka, Ildikó

“…The aim of this study was to optimize the formulation of meloxicam (MEL)-containing human serum albumin (HSA) nanoparticles for nose-to-brain via a quality by…”
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Effects of sub-chronic, in vivo administration of sigma non-opioid intracellular receptor 1 ligands on platelet and aortic arachidonate cascade in rats by Váczi, Sándor, Barna, Lilla, Laczi, Krisztián, Tömösi, Ferenc, Rákhely, Gábor, Penke, Botond, Fülöp, Lívia, Bogár, Ferenc, Janáky, Tamás, Deli, Mária A., Mezei, Zsófia

“…Platelets regulate cell-cell interactions and local circulation through eicosanoids from arachidonic acid. Sigma non-opioid intracellular receptor 1 (sigma-1…”
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Indoleamine 2,3-Dioxygenase Cannot Inhibit Chlamydia trachomatis Growth in HL-60 Human Neutrophil Granulocytes by Virok, Dezső P, Tömösi, Ferenc, Keller-Pintér, Anikó, Szabó, Kitti, Bogdanov, Anita, Poliska, Szilárd, Rázga, Zsolt, Bruszel, Bella, Cseh, Zsuzsanna, Kókai, Dávid, Paróczai, Dóra, Endrész, Valéria, Janáky, Tamás, Burián, Katalin

“…Neutrophil granulocytes are the major cells involved in ( )-mediated inflammation and histopathology. A key protein in human intracellular antichlamydial…”
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Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array by May, Caroline, Nordhoff, Eckhard, Casjens, Swaantje, Turewicz, Michael, Eisenacher, Martin, Gold, Ralf, Brüning, Thomas, Pesch, Beate, Stephan, Christian, Woitalla, Dirk, Penke, Botond, Janáky, Tamás, Virók, Dezső, Siklós, László, Engelhardt, Jozsef I, Meyer, Helmut E

“…Amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron disorder, is characterized by the progressive and selective loss of upper and…”
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Noninvasive embryo viability assessment by quantitation of human haptoglobin alpha-1 fragment in the in vitro fertilization culture medium: an additional tool to increase success rate by Montskó, Gergely, Ph.D, Zrínyi, Zita, M.S, Janáky, Tamás, D.Sc, Szabó, Zoltán, Ph.D, Várnagy, Ákos, M.D., Ph.D, Kovács, Gábor L., M.D., D.Sc, Bódis, József, M.D., D.Sc

“…Objective To find new candidate molecules to assess embryo viability in a noninvasive manner. Design Prospective, blinded study with randomized sample…”
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Investigation of the Absorption of Nanosized lamotrigine Containing Nasal Powder via the Nasal Cavity by Ambrus, Rita, Gieszinger, Péter, Gáspár, Róbert, Sztojkov-Ivanov, Anita, Ducza, Eszter, Márki, Árpád, Janáky, Tamás, Tömösi, Ferenc, Kecskeméti, Gábor, Szabó-Révész, Piroska, Bartos, Csilla

“…Nasal drug delivery has become a popular research field in the last years. This is not surprising since the nose possesses unique anatomical and physical…”
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O -GlcNAcylation Suppresses the Ion Current IClswell by Preventing the Binding of the Protein ICln to α-Integrin by Costa, Roberta, Remigante, Alessia, Civello, Davide A, Bernardinelli, Emanuele, Szabó, Zoltán, Morabito, Rossana, Marino, Angela, Sarikas, Antonio, Patsch, Wolfgang, Paulmichl, Markus, Janáky, Tamás, Miseta, Attila, Nagy, Tamás, Dossena, Silvia

“…-GlcNAcylation is a post-translational modification of proteins that controls a variety of cellular processes, is chronically elevated in diabetes mellitus,…”
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