Search Results - "Jana, Arundhati"

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation by Jambusaria, Ankit, Hong, Zhigang, Zhang, Lianghui, Srivastava, Shubhi, Jana, Arundhati, Toth, Peter T, Dai, Yang, Malik, Asrar B, Rehman, Jalees

“…Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but little is known about their characteristic gene expression…”
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Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson’s Disease Via Astrocytic GDNF by Patel, Dhruv, Jana, Arundhati, Roy, Avik, Pahan, Kalipada

“…Glial cell line-derived neurotrophic factor (GDNF) has potent neurotrophic effects and is known to promote the dopaminergic (DA) neuronal survival in cellular…”
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Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Reduces Microglial and Astroglial Inflammatory Responses by Brahmachari, Saurav, Jana, Arundhati, Pahan, Kalipada

“…Upon activation, microglia and astrocytes produce a number of proinflammatory molecules that participate in the pathophysiology of several neurodegenerative…”
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Can concomitant use of zinc and curcumin with other immunity‐boosting nutraceuticals be the arsenal against COVID‐19? by Roy, Anupam, Sarkar, Biswatrish, Celik, Cagla, Ghosh, Animesh, Basu, Utpal, Jana, Malabendu, Jana, Arundhati, Gencay, Ayse, Can Sezgin, Gulten, Ildiz, Nilay, Dam, Paulami, Mandal, Amit Kumar, Ocsoy, Ismail

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Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer’s disease by Jana, Arundhati, Wang, Xinge, Leasure, Joseph W., Magana, Lissette, Wang, Li, Kim, Young-Mee, Dodiya, Hemraj, Toth, Peter T., Sisodia, Sangram S., Rehman, Jalees

“…Blood–brain barrier (BBB) dysfunction is emerging as a key pathogenic factor in the progression of Alzheimer’s disease (AD), where increased microvascular…”
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A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease by Modi, Khushbu K, Jana, Arundhati, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada

“…Alzheimer's disease (AD), the leading cause of dementia in the aging population, is characterized by the presence of neuritic plaques, neurofibrillary tangles…”
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Nuclear translocation of mitochondrial dehydrogenases as an adaptive cardioprotective mechanism by Srivastava, Shubhi, Gajwani, Priyanka, Jousma, Jordan, Miyamoto, Hiroe, Kwon, Youjeong, Jana, Arundhati, Toth, Peter T., Yan, Gege, Ong, Sang-Ging, Rehman, Jalees

“…Chemotherapy-induced cardiac damage remains a leading cause of death amongst cancer survivors. Anthracycline-induced cardiotoxicity is mediated by severe…”
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Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer by Jana, Arundhati, Das, Archita, Krett, Nancy L, Guzman, Grace, Thomas, Alexandra, Mancinelli, Georgina, Bauer, Jessica, Ushio-Fukai, Masuko, Fukai, Tohru, Jung, Barbara

“…Colorectal cancer remains a deadly cancer due to metastatic disease. To understand the molecular mechanisms of metastasis in colon cancer, we investigated…”
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Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease by Roy, Avik, Ghosh, Anamitra, Jana, Arundhati, Liu, Xiaojuan, Brahmachari, Saurav, Gendelman, Howard E, Pahan, Kalipada

“…Neuroinflammation and oxidative stress underlie the pathogenesis of various neurodegenerative disorders. Here we demonstrate that sodium phenylbutyrate (NaPB),…”
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Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer by Staudacher, Jonas J., Bauer, Jessica, Jana, Arundhati, Tian, Jun, Carroll, Timothy, Mancinelli, Georgina, Özden, Özkan, Krett, Nancy, Guzman, Grace, Kerr, David, Grippo, Paul, Jung, Barbara

“…Advanced colorectal cancer (CRC) remains a critical health care challenge worldwide. Various TGF-β superfamily members are important in colorectal cancer…”
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NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway by Jana, Arundhati, Krett, Nancy L, Guzman, Grace, Khalid, Ahmer, Ozden, Ozkan, Staudacher, Jonas J, Bauer, Jessica, Baik, Seung Hyun, Carroll, Timothy, Yazici, Cemal, Jung, Barbara

“…Colorectal cancer (CRC) remains a common and deadly cancer due to metastatic disease. Activin and TGFB (TGFβ) signaling are growth suppressive pathways that…”
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Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis by Jana, Arundhati, Pahan, Kalipada

“…Multiple sclerosis (MS) is the most common human demyelinating disease of the central nervous system where oxidative stress has been proposed to play an…”
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Up-Regulation of Neurotrophic Factors by Cinnamon and its Metabolite Sodium Benzoate: Therapeutic Implications for Neurodegenerative Disorders by Jana, Arundhati, Modi, Khushbu K., Roy, Avik, Anderson, John A., van Breemen, Richard B., Pahan, Kalipada

“…This study underlines the importance of cinnamon, a widely-used food spice and flavoring material, and its metabolite sodium benzoate (NaB), a widely-used food…”
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Correction: A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease by Modi, Khushbu K, Jana, Arundhati, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada

“…[This corrects the article DOI: 10.1371/journal.pone.0103606.]…”
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Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer by Ozden, Ozkan, Bishehsari, Faraz, Bauer, Jessica, Park, Seong-Hoon, Jana, Arundhati, Baik, Seung Hyun, Sporn, Judith C., Staudacher, Jonas J., Yazici, Cemal, Krett, Nancy, Jung, Barbara

“…BRCA1-associated RING domain protein 1 (BARD1) stabilizes BRCA1 protein by forming a heterodimeric RING-RING complex and impacts function of BRCA1, including…”
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Oxidative Stress Kills Human Primary Oligodendrocytes Via Neutral Sphingomyelinase: Implications for Multiple Sclerosis by Jana, Arundhati, Pahan, Kalipada

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Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease by Jana, Arundhati, Pahan, Kalipada

“…Glial activation plays an important role in the pathogenesis of various neurodegenerative disorders including Alzheimer's disease. However, molecular…”
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Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death by Miller, Nichole M, Shriver, Leah P, Bodiga, Vijaya L, Ray, Avijit, Basu, Sreemanti, Ahuja, Rajiv, Jana, Arundhati, Pahan, Kalipada, Dittel, Bonnie N

“…MS (multiple sclerosis) is the most prevalent autoimmune disease of the CNS (central nervous system) historically characterized as an inflammatory and…”
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Sphingolipids in Multiple Sclerosis by Jana, Arundhati, Pahan, Kalipada

“…Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the CNS. Oligodendrocytes, the myelin-forming cells of the central nervous system…”
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Corrigendum to “Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis” [Cytokine 174 (2024) 156457] by Jana, Malabendu, Mondal, Susanta, Jana, Arundhati, Pahan, Kalipada

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