Search Results - "Jan Simon"

Light‐Controlled Destruction and Assembly: Switching between Two Differently Composed Cage‐Type Complexes by Hugenbusch, Daniel, Lehr, Marc, Glasenapp, Jan‐Simon, McConnell, Anna J., Herges, Rainer

“…We report on two regioisomeric, diazocine ligands 1 and 2 that can both be photoswitched between the E‐ and Z‐configurations with violet and green light. The…”
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Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials by Franz, Sandra, Rammelt, Stefan, Scharnweber, Dieter, Simon, Jan C

“…Abstract A key for long-term survival and function of biomaterials is that they do not elicit a detrimental immune response. As biomaterials can have profound…”
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JAK‐inhibitors in dermatology – small molecules, big impact? Overview of the mechanism of action, previous study results and potential adverse effects by Klein, Benjamin, Treudler, Regina, Simon, Jan C.

“…Summary Numerous chronic inflammatory skin diseases are associated with the release of proinflammatory cytokines, which act via the intracellular JAK‐STAT…”
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Detergent Chemistry Modulates the Transgression of Planetary Boundaries including Antimicrobial Resistance and Drug Discovery by Seewald, Marc, Nielinger, Lena, Alker, Katharina, Behnke, Jan‐Simon, Wycisk, Virginia, Urner, Leonhard H.

“…Detergent chemistry enables applications in the world today while harming safe operating spaces that humanity needs for survival. Aim of this review is to…”
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Necropolitics Beyond the Exception: Parapolicing, Milícia Urbanism, and the Assassination of Marielle Franco in Rio de Janeiro by Hutta, Jan Simon

“…Engaging with the assassination of black city councillor Marielle Franco, the paper discusses how “milícia urbanism”, a formation of power and capital…”
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Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial by Leiter, Ulrike, Dr, Stadler, Rudolf, MD, Mauch, Cornelia, Prof, Hohenberger, Werner, Prof, Brockmeyer, Norbert, Prof, Berking, Carola, Prof, Sunderkötter, Cord, Prof, Kaatz, Martin, MD, Schulte, Klaus-Werner, MD, Lehmann, Percy, MD, Vogt, Thomas, Prof, Ulrich, Jens, MD, Herbst, Rudolf, MD, Gehring, Wolfgang, MD, Simon, Jan-Christoph, Prof, Keim, Ulrike, PhD, Martus, Peter, Prof, Garbe, Claus, Prof

“…Summary Background Complete lymph node dissection is recommended in patients with positive sentinel lymph node biopsy results. To date, the effect of complete…”
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Synthesis of N‐Substituted Pyrrole‐2,5‐dicarboxylic Acids from Pyrroles by Jeshua Friedrichs, Jan‐Simon, Schmermund, Luca, Urmann, Corinna, Sieber, Volker

“…Pyrrole‐2,5‐dicarboxylic acid (PDCA) is a heterocyclic aromatic dicarboxylic acid that may emerge as a new monomer for polyester production. Compared to its…”
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Genome architecture and genetic diversity of allopolyploid okra (Abelmoschus esculentus) by Nieuwenhuis, Ronald, Hesselink, Thamara, Broeck, Hetty C., Cordewener, Jan, Schijlen, Elio, Bakker, Linda, Diaz Trivino, Sara, Struss, Darush, Hoop, Simon‐Jan, Jong, Hans, Peters, Sander A.

“…SUMMARY The allopolyploid okra (Abelmoschus esculentus) unveiled telomeric repeats flanking distal gene‐rich regions and short interstitial TTTAGGG telomeric…”
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Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice by Lohmann, Nadine, Schirmer, Lucas, Atallah, Passant, Wandel, Elke, Ferrer, Ruben A, Werner, Carsten, Simon, Jan C, Franz, Sandra, Freudenberg, Uwe

“…Excessive production of inflammatory chemokines can cause chronic inflammation and thus impair cutaneous wound healing. Capturing chemokine signals using wound…”
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Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks by Friedemann, Markus, Kalbitzer, Liv, Franz, Sandra, Moeller, Stephanie, Schnabelrauch, Matthias, Simon, Jan‐Christoph, Pompe, Tilo, Franke, Katja

“…Dynamic alterations of composition and mechanics of the extracellular matrix are suggested to modulate cellular behavior including plasticity of macrophages…”
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Emergence of mass spectrometry detergents for membrane proteomics by Behnke, Jan-Simon, Urner, Leonhard H.

“…Detergents enable the investigation of membrane proteins by mass spectrometry. Detergent designers aim to improve underlying methodologies and are confronted…”
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Azimuthal Dipolar Rotor Arrays on Surfaces by Hamer, Sebastian, Glasenapp, Jan‐Simon, Röhricht, Fynn, Li, Chao, Berndt, Richard, Herges, Rainer

“…A set of dipolar molecular rotor compounds was designed, synthesized and adsorbed as self‐assembled 2D arrays on Ag(111) surfaces. The title molecules are…”
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Triplet sensitization enables bidirectional isomerization of diazocine with 130 nm redshift in excitation wavelengths by Isokuortti, Jussi, Griebenow, Thomas, Glasenapp, Jan-Simon von, Raeker, Tim, Filatov, Mikhail A, Laaksonen, Timo, Herges, Rainer, Durandin, Nikita A

“…Diazocines are bridged azobenzenes with phenyl rings connected by a CH 2 -CH 2 group. Despite this rather small structural difference, diazocine exhibits…”
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Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial by Zimmer, Lisa, Livingstone, Elisabeth, Hassel, Jessica C, Fluck, Michael, Eigentler, Thomas, Loquai, Carmen, Haferkamp, Sebastian, Gutzmer, Ralf, Meier, Friedegund, Mohr, Peter, Hauschild, Axel, Schilling, Bastian, Menzer, Christian, Kieker, Felix, Dippel, Edgar, Rösch, Alexander, Simon, Jan-Christoph, Conrad, Beate, Körner, Silvia, Windemuth-Kieselbach, Christine, Schwarz, Leonora, Garbe, Claus, Becker, Jürgen C, Schadendorf, Dirk, Berking, Carola, Herbst, Rudolf A, Martens, Uwe M, Sell, Sabine, Stadler, Rudolf, Terheyden, Patrick, Utikal, Jochen

“…Nivolumab and ipilimumab, alone or in combination, are widely used immunotherapeutic treatment options for patients with advanced—ie, unresectable or…”
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Developments and perspectives in allergology by Treudler, Regina, Simon, Jan‐Christoph

“…Summary Allergology is a key part of dermatological care. This paper reviews current pathophysiological, diagnostic and therapeutic developments in…”
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Atopic dermatitis and psychosocial comorbidities by Kage, Paula, Simon, Jan‐Christoph, Treudler, Regina

“…Summary Atopic dermatitis (AD) is a chronic inflammatory disease that may be associated with a number of comorbidities including psychosocial disorders, which…”
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Psoriasis: Obesity and Fatty Acids by Kunz, Manfred, Simon, Jan C, Saalbach, Anja

“…Psoriasis is chronic inflammatory skin disease affecting skin, joints, cardiovascular system, brain, and metabolism. The pathogenesis of psoriasis is mediated…”
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Case of atopic eczema treated with dupilumab throughout conception, pregnancy, and lactation by Kage, Paula, Simon, Jan‐Christoph, Treudler, Regina

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High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players by Herbert, Diana, Franz, Sandra, Popkova, Yulia, Anderegg, Ulf, Schiller, Jürgen, Schwede, Katharina, Lorz, Axel, Simon, Jan C., Saalbach, Anja

“…In obesity, hypertrophic adipocytes secrete high amounts of adipocytokines, resulting in low-grade inflammation amplified by infiltrating proinflammatory…”
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Managing immune checkpoint-inhibitor-induced severe autoimmune-like hepatitis by liver-directed topical steroids by Ziemer, Mirjana, Koukoulioti, Eleni, Beyer, Susanne, Simon, Jan C, Berg, Thomas

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