Search Results - "Jan, L. Y."

Role of ER Export Signals in Controlling Surface Potassium Channel Numbers by Ma, Dzwokai, Zerangue, Noa, Lin, Yu-Fung, Collins, Anthony, Yu, Mei, Jan, Yuh Nung, Jan, Lily Yeh

“…Little is known about the identity of endoplasmic reticulum (ER) export signals and how they are used to regulate the number of proteins on the cell surface…”
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Adherens junctions inhibit asymmetric division in the Drosophila epithelium by Jan, Yuh Nung, Lu, Bingwei, Roegiers, Fabrice, Jan, Lily Y

“…Asymmetric division is a fundamental mechanism for generating cellular diversity. In the central nervous system of Drosophila, neural progenitor cells called…”
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Genes regulating dendritic outgrowth, branching, and routing in Drosophila by Gao, F B, Brenman, J E, Jan, L Y, Jan, Y N

“…Signaling between neurons requires highly specialized subcellular structures, including dendrites and axons. Dendrites exhibit diverse morphologies yet little…”
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Evidence for Presynaptic N-Methyl-D-Aspartate Autoreceptors in the Spinal Cord Dorsal Horn by Liu, H., Wang, H., Sheng, M., Jan, L. Y., Jan, Y. N., Basbaum, A. I.

“…The N-methyl-D-aspartate (NMDA) receptor has been implicated in a variety of systems that undergo plastic changes in the central nervous system. We used…”
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Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion by Luo, L, Liao, Y J, Jan, L Y, Jan, Y N

“…The small GTPases of the Rac/Rho/Cdc42 subfamily are implicated in actin cytoskeleton-membrane interaction in mammalian cells and budding yeast. The in vivo…”
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Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction by Whistler, J L, Chuang, H H, Chu, P, Jan, L Y, von Zastrow, M

“…Opiate analgesia, tolerance, and addiction are mediated by drug-induced activation of the mu opioid receptor. A fundamental question in addiction biology is…”
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Asymmetric segregation of Numb and Prospero during cell division by Knoblich, Jürgen A, Jan, Nung Jan, Yuh

“…A cell can divide asymmetrically by specifically segregating a determinant into one of its daughter cells. The Numb protein is a candidate for such a…”
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Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines by Luo, Liqun, Hensch, Takao K, Ackerman, Larry, Barbel, Sandra, Jan, Lily Y, Nung Jan, Yuh

“…Neurons contain distinct compartments including dendrites, dendritic spines, axons and synaptic terminals. The molecular mechanisms that generate and…”
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Primary structure and functional expression of a mouse inward rectifier potassium channel by Kubo, Yoshihiro, Baldwin, Timothy J, Nung Jan, Yuh, Jan, Lily Y

“…A complementary DNA encoding an inward rectifier K+ channel (IRK1) was isolated from a mouse macrophage cell line by expression cloning. This channel conducts…”
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Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence by Murre, C, McCaw, P S, Vaessin, H, Caudy, M, Jan, L Y, Jan, Y N, Cabrera, C V, Buskin, J N, Hauschka, S D, Lassar, A B

“…A DNA binding and dimerization motif, with apparent amphipathic helices (the HLH motif), has recently been identified in various proteins, including two that…”
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Cell interactions and gene interactions in peripheral neurogenesis by GHYSEN, A, DAMBLY-CHAUDIERE, C, JAN, L. Y, YUH-NUNG JAN

“…In this review we will concentrate on the early part of the process-the singling out of the precursor cells-using the sensory bristles of the adult Drosophila…”
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The Drosophila Numb Protein Inhibits Signaling of the Notch Receptor during Cell-Cell Interaction in Sensory Organ Lineage by Frise, Erwin, Knoblich, Jürgen A., Younger-Shepherd, Susan, Jan, Lily Y., Jan, Yuh Nung

“…Specification of unequal daughter cell fates in the Drosophila external sense organ lineage requires asymmetric localization of the intrinsic determinant Numb…”
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Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage by Zeng, C, Younger-Shepherd, S, Jan, L Y, Jan, Y N

“…Asymmetric divisions allow a precursor to produce four distinct cells of a Drosophila sensory organ lineage (SOL). Whereas this process requires cell-cell…”
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Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel by Kubo, Yoshihiro, Reuveny, Eitan, Slesinger, Paul A, Jan, Yuh Nung, Jan, Lily Y

“…Parasympathetic nerve stimulation causes slowing of the heart rate by activation of muscarinic receptors and the subsequent opening of muscarinic K+ channels…”
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Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation by Doherty, D, Feger, G, Younger-Shepherd, S, Jan, L Y, Jan, Y N

“…Wing margin formation in Drosophila requires the Notch receptor and, in the dorsal compartment, one of its ligands, Serrate. We provide evidence that Delta,…”
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rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster by BIER, E, JAN, L. Y, YUH NUNG JAN

“…rhomboid (rho) belongs to a group of four genes involved in the elaboration of positional information at a ventrolateral level in the Drosophila embryo…”
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Dendrites by Jan, Y N, Jan, L Y

“…Synapse formation involves two partners, axons and dendrites. The axon of a presynaptic neuron needs to be properly guided to make synapses with the correct…”
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Bazooka and Atypical Protein Kinase C are Required to Regulate Oocyte Differentiation in the Drosophila Ovary by Cox, Daniel N., Seyfried, Salim Abdelilah, Jan, Lily Yeh, Jan, Yuh Nung

“…The par genes, identified by their role in the establishment of anterior-posterior polarity in the Caenorhabditis elegans zygote, subsequently have been shown…”
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Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila by Ruohola, H, Bremer, K A, Baker, D, Swedlow, J R, Jan, L Y, Jan, Y N

“…Oogenesis in Drosophila involves specification of both germ cells and the surrounding somatic follicle cells, as well as the determination of oocyte polarity…”
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atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system by Jarman, A P, Grau, Y, Jan, L Y, Jan, Y N

“…In the Drosophila peripheral nervous system, proneural genes of the achaete-scute complex (ASC) are required for formation of the precursors of external sense…”
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