Search Results - "Jamshad, Mohammed"

Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins by Jamshad, Mohammed, Grimard, Vinciane, Idini, Ilaria, Knowles, Tim J., Dowle, Miriam R., Schofield, Naomi, Sridhar, Pooja, Lin, Yupin, Finka, Rachael, Wheatley, Mark, Thomas, Owen R. T., Palmer, Richard E., Overduin, Michael, Govaerts, Cédric, Ruysschaert, Jean-Marie, Edler, Karen J., Dafforn, Tim R.

“…In the past few years there has been a growth in the use of nanoparticles for stabilizing lipid membranes that contain embedded proteins. These…”
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Detergent-free purification of ABC (ATP-binding-cassette) transporters by Gulati, Sonali, Jamshad, Mohammed, Knowles, Timothy J, Morrison, Kerrie A, Downing, Rebecca, Cant, Natasha, Collins, Richard, Koenderink, Jan B, Ford, Robert C, Overduin, Michael, Kerr, Ian D, Dafforn, Timothy R, Rothnie, Alice J

“…ABC (ATP-binding-cassette) transporters carry out many vital functions and are involved in numerous diseases, but study of the structure and function of these…”
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Structural and Functional Analysis of the Escherichia coli Acid-Sensing Histidine Kinase EvgS by Sen, Hrishiraj, Aggarwal, Nikhil, Ishionwu, Chibueze, Hussain, Nosheen, Parmar, Chandni, Jamshad, Mohammed, Bavro, Vassiliy N, Lund, Peter A

“…The EvgS/EvgA two-component system of is activated in response to low pH and alkali metals and regulates many genes, including those for the…”
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MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis by Isom, Georgia L., Davies, Nathaniel J., Chong, Zhi-Soon, Bryant, Jack A., Jamshad, Mohammed, Sharif, Maria, Cunningham, Adam F., Knowles, Timothy J., Chng, Shu-Sin, Cole, Jeffrey A., Henderson, Ian R.

“…Bacterial proteins with MCE domains were first described as being important for M ammalian C ell E ntry. More recent evidence suggests they are components of…”
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The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity by Jamshad, Mohammed, Knowles, Timothy J, White, Scott A, Ward, Douglas G, Mohammed, Fiyaz, Rahman, Kazi Fahmida, Wynne, Max, Hughes, Gareth W, Kramer, Günter, Bukau, Bernd, Huber, Damon

“…In bacteria, the translocation of proteins across the cytoplasmic membrane by the Sec machinery requires the ATPase SecA. SecA binds ribosomes and recognises…”
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Production, purification and characterization of recombinant, full-length human claudin-1 by Bonander, Nicklas, Jamshad, Mohammed, Oberthür, Dominik, Clare, Michelle, Barwell, James, Hu, Ke, Farquhar, Michelle J, Stamataki, Zania, Harris, Helen J, Dierks, Karsten, Dafforn, Timothy R, Betzel, Christian, McKeating, Jane A, Bill, Roslyn M

“…The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1,…”
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A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81 by Grove, Joe, Hu, Ke, Farquhar, Michelle J, Goodall, Margaret, Walker, Lucas, Jamshad, Mohammed, Drummer, Heidi E, Bill, Roslyn M, Balfe, Peter, McKeating, Jane A

“…Tetraspanins are small transmembrane proteins, found in all higher eukaryotes, that compartmentalize cellular membranes through interactions with partner…”
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Identification, Mutagenesis, and Transcriptional Analysis of the Methanesulfonate Transport Operon of Methylosulfonomonas methylovora by JAMSHAD, Mohammed, DE MARCO, Paolo, PACHECO, Catarina C, HANCZAR, Timea, MURRELL, J. Colin

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A method for detergent-free isolation of membrane proteins in their local lipid environment by Lee, Sarah C, Knowles, Tim J, Postis, Vincent L G, Jamshad, Mohammed, Parslow, Rosemary A, Lin, Yu-pin, Goldman, Adrian, Sridhar, Pooja, Overduin, Michael, Muench, Stephen P, Dafforn, Timothy R

“…This protocol from Lee et al . describes a method for the extraction of membrane proteins in their native lipid environment using styrene maleic anhydride…”
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SecA Cotranslationally Interacts with Nascent Substrate Proteins In Vivo by Huber, Damon, Jamshad, Mohammed, Hanmer, Ruby, Schibich, Daniela, Döring, Kristina, Marcomini, Isabella, Kramer, Günter, Bukau, Bernd

“…SecA is an essential component of the Sec machinery in bacteria, which is responsible for transporting proteins across the cytoplasmic membrane. Recent work…”
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Isomerization of BRCA1–BARD1 promotes replication fork protection by Daza-Martin, Manuel, Starowicz, Katarzyna, Jamshad, Mohammed, Tye, Stephanie, Ronson, George E., MacKay, Hannah L., Chauhan, Anoop Singh, Walker, Alexandra K., Stone, Helen R., Beesley, James F. J., Coles, Jennifer L., Garvin, Alexander J., Stewart, Grant S., McCorvie, Thomas J., Zhang, Xiaodong, Densham, Ruth M., Morris, Joanna R.

“…The integrity of genomes is constantly threatened by problems encountered by the replication fork. BRCA1, BRCA2 and a subset of Fanconi anaemia proteins…”
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The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms by Garvin, Alexander J, Walker, Alexandra K, Densham, Ruth M, Chauhan, Anoop Singh, Stone, Helen R, Mackay, Hannah L, Jamshad, Mohammed, Starowicz, Katarzyna, Daza-Martin, Manuel, Ronson, George E, Lanz, Alexander J, Beesley, James F, Morris, Joanna R

“…SUMOylation (small ubiquitin-like modifier) in the DNA double-strand break (DSB) response regulates recruitment, activity, and clearance of repair factors…”
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G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent by Jamshad, Mohammed, Charlton, Jack, Lin, Yu-Pin, Routledge, Sarah J, Bawa, Zharain, Knowles, Timothy J, Overduin, Michael, Dekker, Niek, Dafforn, Tim R, Bill, Roslyn M, Poyner, David R, Wheatley, Mark

“…G-protein coupled receptors (GPCRs) constitute the largest class of membrane proteins and are a major drug target. A serious obstacle to studying GPCR…”
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Ligand-induced conformational changes in a SMALP-encapsulated GPCR by Routledge, Sarah J., Jamshad, Mohammed, Little, Haydn A., Lin, Yu-Pin, Simms, John, Thakker, Alpesh, Spickett, Corinne M., Bill, Roslyn M., Dafforn, Tim R., Poyner, David R., Wheatley, Mark

“…The adenosine 2A receptor (A2AR), a G-protein-coupled receptor (GPCR), was solubilised and purified encapsulated in styrene maleic acid lipid particles…”
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Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a by Paulin, Sarah, Jamshad, Mohammed, Dafforn, Timothy R, Garcia-Lara, Jorge, Foster, Simon J, Galley, Nicola F, Roper, David I, Rosado, Helena, Taylor, Peter W

“…Surfactant-mediated removal of proteins from biomembranes invariably results in partial or complete loss of function and disassembly of multi-protein…”
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Iron is a ligand of SecA-like metal-binding domains in vivo by Cranford-Smith, Tamar, Jamshad, Mohammed, Jeeves, Mark, Chandler, Rachael A., Yule, Jack, Robinson, Ashley, Alam, Farhana, Dunne, Karl A., Aponte Angarita, Edwin H., Alanazi, Mashael, Carter, Cailean, Henderson, Ian R., Lovett, Janet E., Winn, Peter, Knowles, Timothy, Huber, Damon

“…The ATPase SecA is an essential component of the bacterial Sec machinery, which transports proteins across the cytoplasmic membrane. Most SecA proteins contain…”
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Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system by Hughes, Gareth W., Hall, Stephen C. L., Laxton, Claire S., Sridhar, Pooja, Mahadi, Amirul H., Hatton, Caitlin, Piggot, Thomas J., Wotherspoon, Peter J., Leney, Aneika C., Ward, Douglas G., Jamshad, Mohammed, Spana, Vaclav, Cadby, Ian T., Harding, Christopher, Isom, Georgia L., Bryant, Jack A., Parr, Rebecca J., Yakub, Yasin, Jeeves, Mark, Huber, Damon, Henderson, Ian R., Clifton, Luke A., Lovering, Andrew L., Knowles, Timothy J.

“…The Mla pathway is believed to be involved in maintaining the asymmetrical Gram-negative outer membrane via retrograde phospholipid transport. The pathway is…”
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Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ by Lee, Sarah C., Collins, Richard, Lin, Yu-pin, Jamshad, Mohammed, Broughton, Claire, Harris, Sarah A., Hanson, Benjamin S, Tognoloni, Cecilia, Parslow, Rosemary A., Terry, Ann E., Rodger, Alison, Smith, Corinne J., Edler, Karen J., Ford, Robert, Roper, David I., Dafforn, Timothy R.

“…The E . coli membrane protein ZipA, binds to the tubulin homologue FtsZ, in the early stage of cell division. We isolated ZipA in a Styrene Maleic Acid lipid…”
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GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential by Wheatley, Mark, Charlton, Jack, Jamshad, Mohammed, Routledge, Sarah J, Bailey, Sian, La-Borde, Penelope J, Azam, Maria T, Logan, Richard T, Bill, Roslyn M, Dafforn, Tim R, Poyner, David R

“…G-protein-coupled receptors (GPCRs) form the largest class of membrane proteins and are an important target for therapeutic drugs. These receptors are highly…”
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Surfactant-free purification of membrane proteins with intact native membrane environment by Jamshad, Mohammed, Lin, Yu-Pin, Knowles, Timothy J, Parslow, Rosemary A, Harris, Craig, Wheatley, Mark, Poyner, David R, Bill, Roslyn M, Thomas, Owen R T, Overduin, Michael, Dafforn, Tim R

“…In order to study the structure and function of a protein, it is generally required that the protein in question is purified away from all others. For soluble…”
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