Search Results - "Jamroskovic, Jan"

A Light‐up Logic Platform for Selective Recognition of Parallel G‐Quadruplex Structures via Disaggregation‐Induced Emission by Deiana, Marco, Chand, Karam, Jamroskovic, Jan, Obi, Ikenna, Chorell, Erik, Sabouri, Nasim

“…The design of turn‐on dyes with optical signals sensitive to the formation of supramolecular structures provides fascinating and underexplored opportunities…”
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Variability in DPA and Calcium Content in the Spores of Clostridium Species by Jamroskovic, Jan, Chromikova, Zuzana, List, Cornelia, Bartova, Barbora, Barak, Imrich, Bernier-Latmani, Rizlan

“…Spores of a number of clostridial species, and their resistance to thermal treatment is a major concern for the food industry. Spore resistance to wet heat is…”
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Combined scanning transmission X-ray and electron microscopy for the characterization of bacterial endospores by Jamroskovic, Jan, Shao, Paul P., Suvorova, Elena, Barak, Imrich, Bernier-Latmani, Rizlan

“…Abstract Endospores (also referred to as bacterial spores) are bacterial structures formed by several bacterial species of the phylum Firmicutes. Spores form…”
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Probing the folding pathways of four-stranded intercalated cytosine-rich motifs at single base-pair resolution by Jamroskovic, Jan, Deiana, Marco, Sabouri, Nasim

“…Cytosine-rich DNA can fold into four-stranded intercalated structures called i-motifs (iMs) under acidic conditions through the formation of hemi-protonated…”
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Unravelling the cellular emission fingerprint of the benchmark G-quadruplex-interactive compound Phen-DC 3 by Deiana, Marco, Jamroskovic, Jan, Obi, Ikenna, Sabouri, Nasim

“…Phen-DC is among the most commonly used G-quadruplex (G4)-stabilizers in vitro and in cells. Here, we show that the G4-interactive binding interactions enable…”
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Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a Thioflavin T-Displacement Assay as a Tool by Jamroskovic, Jan, Livendahl, Madeleine, Eriksson, Jonas, Chorell, Erik, Sabouri, Nasim

“…Small molecules are used in the G‐quadruplex (G4) research field in vivo and in vitro, and there are increasing demands for ligands that selectively stabilize…”
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A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA by Deiana, Marco, Chand, Karam, Jamroskovic, Jan, Das, Rabindra Nath, Obi, Ikenna, Chorell, Erik, Sabouri, Nasim

“…Direct and unambiguous evidence of the formation of G-quadruplexes (G4s) in human cells have shown their implication in several key biological events and has…”
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Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication by Obi, Ikenna, Rentoft, Matilda, Singh, Vandana, Jamroskovic, Jan, Chand, Karam, Chorell, Erik, Westerlund, Fredrik, Sabouri, Nasim

“…Abstract G-quadruplex (G4) structures are stable non-canonical DNA structures that are implicated in the regulation of many cellular pathways. We show here…”
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Identification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assay by Jamroskovic, Jan, Obi, Ikenna, Movahedi, Anahita, Chand, Karam, Chorell, Erik, Sabouri, Nasim

“…[Display omitted] •Validation of a new qPCR assay, the “qPCR stop assay”, to examine G4 DNA formation.•The G4 ligand PhenDC3 selectively stabilizes predicted…”
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Flexible Versus Rigid G‐Quadruplex DNA Ligands: Synthesis of Two Series of Bis‐indole Derivatives and Comparison of Their Interactions with G‐Quadruplex DNA by Prasad, Bagineni, Jamroskovic, Jan, Bhowmik, Sudipta, Kumar, Rajendra, Romell, Tajanena, Sabouri, Nasim, Chorell, Erik

“…Small molecules that target G‐quadruplex (G4) DNA structures are not only valuable to study G4 biology but also for their potential as therapeutics. This work…”
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The Relation Between Position and Chemical Composition of Bis‐Indole Substituents Determines Their Interactions with G‐Quadruplex DNA by Prasad, Bagineni, Das, Rabindra Nath, Jamroskovic, Jan, Kumar, Rajendra, Hedenström, Mattias, Sabouri, Nasim, Chorell, Erik

“…G‐quadruplex (G4) DNA structures are linked to fundamental biological processes and human diseases, which has triggered the development of compounds that…”
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Lipid domains in Bacillus subtilis anucleate cells by MUCHOVA, Katarína, JAMROSKOVIC, Ján, BARAK, Imrich

“…Bacterial membranes are known to form domains with specific lipid compositions and functions. Recently, using membrane binding fluorescent dyes, lipid spiral…”
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Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G‑Quadruplex Stabilization by Jamroskovic, Jan, Doimo, Mara, Chand, Karam, Obi, Ikenna, Kumar, Rajendra, Brännström, Kristoffer, Hedenström, Mattias, Nath Das, Rabindra, Akhunzianov, Almaz, Deiana, Marco, Kasho, Kazutoshi, Sulis Sato, Sebastian, Pourbozorgi, Parham L, Mason, James E, Medini, Paolo, Öhlund, Daniel, Wanrooij, Sjoerd, Chorell, Erik, Sabouri, Nasim

“…The signal transducer and activator of transcription 3 (STAT3) protein is a master regulator of most key hallmarks and enablers of cancer, including cell…”
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Design and Synthesis of 2,2′-Diindolylmethanes to Selectively Target Certain G-Quadruplex DNA Structures by Livendahl, Madeleine, Jamroskovic, Jan, Ivanova, Svetlana, Demirel, Peter, Sabouri, Nasim, Chorell, Erik

“…G‐quadruplex (G4) structures carry vital biological functions, and compounds that selectively target certain G4 structures have both therapeutic potential and…”
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Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a ThioflavinT-Displacement Assay as a Tool by Jamroskovic, Jan, Livendahl, Madeleine, Eriksson, Jonas, Chorell, Erik, Sabouri, Nasim

“…Small molecules are used in the G-quadruplex (G4) research field in vivo and in vitro, and there are increasing demands for ligands that selectively stabilize…”
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A Light‐up Logic Platform for Selective Recognition of Parallel G‐Quadruplex Structures via Disaggregation‐Induced Emission by Deiana, Marco, Chand, Karam, Jamroskovic, Jan, Obi, Ikenna, Chorell, Erik, Sabouri, Nasim

“…The design of turn‐on dyes with optical signals sensitive to the formation of supramolecular structures provides fascinating and underexplored opportunities…”
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Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNA by Livendahl, M, Jamroskovic, J, Hedenström, M, Görlich, T, Sabouri, N, Chorell, E

“…G-quadruplex (G4) DNA structures are involved in many important biological processes and can be linked to several human diseases. Drug-like low molecular…”
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An oscillating Min system in Bacillus subtilis influences asymmetrical septation during sporulation by JAMROSKOVIC, Ján, PAVLENDOVA, Nad'a, MUCHOVA, Katarína, WILKINSON, Anthony J, BARAK, Imrich

“…The Min system plays an important role in ensuring that cell division occurs at mid-cell in rod-shaped bacteria. In Escherichia coli, pole-to-pole oscillation…”
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Oscillating behavior of Clostridium difficile Min proteins in Bacillus subtilis by Makroczyova, Jana, Jamroskovic, Jan, Krascsenitsova, Eva, Labajova, Nad'a, Barak, Imrich

“…In rod‐shaped bacteria, the proper placement of the division septum at the midcell relies, at least partially, on the proteins of the Min system as an…”
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