Search Results - "Jamison, Curtis"
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1
Axon regeneration in the absence of growth cones: Acceleration by cyclic AMP
Published in Journal of comparative neurology (1911) (20-07-2009)“…Regenerative failure of spinal axons is commonly ascribed to signaling of F‐actin depolymerization and growth cone collapse by molecules such as the…”
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The distribution of SNPs in human gene regulatory regions
Published in BMC genomics (06-10-2005)“…As a result of high-throughput genotyping methods, millions of human genetic variants have been reported in recent years. To efficiently identify those with…”
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SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
Published in BMC bioinformatics (05-03-2007)“…There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are…”
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4
Open Bioinformatics
Published in Bioinformatics (12-04-2003)“…Contact: cjamison@gmu.edu…”
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5
Statistical geometry approach to the study of functional effects of human nonsynonymous SNPs
Published in Human mutation (01-11-2005)“…The ability to predict the effect of nonsynonymous SNPs (nsSNPs) on protein function is important for the success of genetic disease association studies. Here…”
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UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model
Published in Pigment cell and melanoma research (01-07-2017)“…Summary Human melanomas exhibit relatively high somatic mutation burden compared to other malignancies. These somatic mutations may produce neoantigens that…”
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Statistical geometry based prediction of nonsynonymous SNP functional effects using random forest and neuro-fuzzy classifiers
Published in Proteins, structure, function, and bioinformatics (01-06-2008)“…There is substantial interest in methods designed to predict the effect of nonsynonymous single nucleotide polymorphisms (nsSNPs) on protein function, given…”
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Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production
Published in BMC developmental biology (12-03-2011)“…The production of nephrons suddenly ends in mice shortly after birth when the remaining cells of the multi-potent progenitor mesenchyme begin to differentiate…”
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Microarrays in Cancer Research
Published in Anticancer research (01-03-2004)“…Microarray technology has presented the scientific community with a compelling approach that allows for simultaneous evaluation of all cellular processes at…”
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Comparative Genomic Sequence Analysis of the Human and Mouse Cystic Fibrosis Transmembrane Conductance Regulator Genes
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2000)“…The identification of the cystic fibrosis transmembrane conductance regulator gene (CFTR) in 1989 represents a landmark accomplishment in human genetics. Since…”
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Ontogenomic study of the relationship between number of gene splice variants and GO categorization
Published in Bioinformatics (15-08-2010)“…Motivation: Splice variation plays important roles in evolution and cancer. Different splice variants of a gene may be characteristic of particular cellular…”
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The EDGE hypothesis: Epigenetically directed genetic errors in repeat-containing proteins (RCPs) involved in evolution, neuroendocrine signaling, and cancer
Published in Frontiers in neuroendocrinology (01-06-2008)“…Abstract Trans-generational epigenetic phenomena, such as contamination with endocrine-disrupting chemicals (EDCs) that decrease fertility and the global…”
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Optimizing T and myeloid cell function in chronic viral infection and cancer
Published 2018“…Chronic viral infections and cancer are major causes of morbidity and mortality around the world. These pathological states persist in part because of…”
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Dissertation -
14
Online analytical processing (OLAP): a fast and effective data mining tool for gene expression databases
Published in Journal of biomedicine & biotechnology (30-06-2005)“…Gene expression databases contain a wealth of information, but current data mining tools are limited in their speed and effectiveness in extracting meaningful…”
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ComboScreen facilitates the multiplex hybridization-based screening of high-density clone arrays
Published in Bioinformatics (01-08-2000)“…Motivation: The construction of physical maps based on bacterial clones [e.g. bacterial artificial chromosomes (BACs)] is valuable for a number of molecular…”
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Structured Query Language (SQL) fundamentals
Published in Current protocols in bioinformatics (01-01-2003)“…Relational databases provide the most common platform for storing data. The Structured Query Language (SQL) is a powerful tool for interacting with relational…”
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Understanding State-Labor Relations in Morsi's Egypt: Moving beyond Islamic Narratives
Published 01-01-2013“…Two presidents have been disposed since the 2011 uprising, both largely the result of mobilization efforts from the country's labor movement. Though Egypt's…”
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Dissertation -
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Understanding State-Labor Relations in Morsi's Egypt: Moving beyond Islamic Narratives
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Dissertation -
19
The SPCH1 Region on Human 7q31: Genomic Characterization of the Critical Interval and Localization of Translocations Associated with Speech and Language Disorder
Published in American journal of human genetics (01-08-2000)“…The KE family is a large three-generation pedigree in which half the members are affected with a severe speech and language disorder that is transmitted as an…”
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Comparative genome mapping in the sequence-based era: early experience with human chromosome 7
Published in Genome research (01-05-2000)“…The success of the ongoing Human Genome Project has resulted in accelerated plans for completing the human genome sequence and the earlier-than-anticipated…”
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