Search Results - "Jamin, Y"

Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma by George, S L, Parmar, V, Lorenzi, F, Marshall, L V, Jamin, Y, Poon, E, Angelini, P, Chesler, L

“…The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT…”
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Diffusion-weighted MRI for imaging cell death after cytotoxic or apoptosis-inducing therapy by Papaevangelou, E, Almeida, G S, Jamin, Y, Robinson, S P, deSouza, N M

“…Background: Non-invasive serial imaging is desirable to detect processes such as necrotic and apoptotic cell death in cancer patients undergoing treatment…”
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The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN by Guan, J, Tucker, E R, Wan, H, Chand, D, Danielson, L S, Ruuth, K, El Wakil, A, Witek, B, Jamin, Y, Umapathy, G, Robinson, S P, Johnson, T W, Smeal, T, Martinsson, T, Chesler, L, Palmer, R H, Hallberg, B

“…The first-in-class inhibitor of ALK, c-MET and ROS1, crizotinib (Xalkori), has shown remarkable clinical efficacy in treatment of ALK-positive non-small cell…”
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The Implications of State Intervention for Self‐Governed Irrigation Schemes: Insights From Tigray, Ethiopia by Oates, N., Hisberg, A., Rodríguez Ros, J., Solomon, H., Ludi, E., Marlet, S., Jamin, J.‐Y.

“…The development of smallholder irrigation is a policy priority in Ethiopia, yet little consideration has been given to the role state interventions play in…”
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Tumour biomechanical response to the vascular disrupting agent ZD6126 in vivo assessed by magnetic resonance elastography by Li, J, Jamin, Y, Boult, J K R, Cummings, C, Waterton, J C, Ulloa, J, Sinkus, R, Bamber, J C, Robinson, S P

“…Background: Magnetic resonance elastography (MRE) is an emerging imaging technique that affords non-invasive quantitative assessment and visualization of…”
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Participatory foresight to address long-term issues in a large irrigation scheme. An example in Office du Niger, Mali by Hertzog, T., Poussin, J.-C., Tangara, B., Jamin, J.-Y.

“…•Investment projects in irrigable land have been developed at large scale in West Africa since 2008.•Expansion of irrigation systems requires a foresight study…”
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The HIF-pathway inhibitor NSC-134754 induces metabolic changes and anti-tumour activity while maintaining vascular function by Baker, L C J, Boult, J K R, Walker-Samuel, S, Chung, Y-L, Jamin, Y, Ashcroft, M, Robinson, S P

“…Background: Hypoxia-inducible factor-1 (HIF-1) mediates the transcriptional response to hypoxic stress, promoting tumour progression and survival. This study…”
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Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI by Beloueche-Babari, M, Jamin, Y, Arunan, V, Walker-Samuel, S, Revill, M, Smith, P D, Halliday, J, Waterton, J C, Barjat, H, Workman, P, Leach, M O, Robinson, S P

“…Background: Non-invasive imaging biomarkers underpin the development of molecularly targeted anti-cancer drugs. This study evaluates tumour apparent diffusion…”
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Formal and informal decision making on water management at the village level: A case study from the Office du Niger irrigation scheme (Mali) by Vandersypen, K, Keita, A.C.T, Coulibaly, Y, Raes, D, Jamin, J.Y

“…1 Water Users Associations (WUAs) are all too often considered a panacea for improving water management in irrigation schemes. Where grassroots movements are…”
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False-negative MRI biomarkers of tumour response to targeted cancer therapeutics by Boult, J K R, Jamin, Y, Jacobs, V, Gilmour, L D, Walker-Samuel, S, Halliday, J, Elvin, P, Ryan, A J, Waterton, J C, Robinson, S P

“…Background: Non-invasive quantitative imaging biomarkers are essential for the evaluation of novel targeted therapeutics. Before deployment in clinical trials,…”
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Drainage problems in the rice schemes of the Office du Niger (Mali) in relation to water management by Vandersypen, K., Keita, A.C.T., Coulibaly, B., Raes, D., Jamin, J.-Y.

“…This paper quantifies the impact of water management on the incidence of drainage problems. It is based on an empirical study in the rice schemes of the Office…”
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Linking Performance and Collective Action--the Case of the Office du Niger Irrigation Scheme in Mali by Vandersypen, K, Verbist, B, Keita, A. C. T, Raes, D, Jamin, J.-Y

“…Increasing irrigation efficiency in irrigation schemes has always been high on the agenda of policy makers. Despite quite some 'social' experiments, whereby…”
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crop needs more than a drop: Towards a new praxis in irrigation management in North Africa by Kuper, M, Bouarfa, S, Errahj, M, Faysse, N, Hammani, A, Hartani, T, Marlet, S, Zairi, A, Bahri, A, Debbarh, A, Garin, P, Jamin, J.-Y, Vincent, B

“…We designed and implemented an action-research programme in large-scale irrigation schemes in Algeria, Morocco and Tunisia, aiming to develop a regional…”
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841 Non-invasive Imaging of Response to MEK Inhibition With Selumetinib (AZD6244, ARRY-142886) in a Human Colorectal Cancer Xenograft Using Diffusion-Weighted MRI by Beloueche-Babari, M, Jamin, Y, Walker-Samuel, S, Smith, P.D, Waterton, J.C, Halliday, J, Barjat, H, Workman, P, Leach, M.O, Robinson, S.P

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Farmers' motivation for collective action in irrigation: a statistical approach applied to the Office du Niger in Mali by Vandersypen, K, Bastiaens, L, Traoré, A, Diakon, B, Raes, D, Jamin, J.-Y

“…This paper provides a statistical approach to evaluate the prospects of farmers' water management using survey data from the Office du Niger irrigation scheme…”
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Sustainability of farmers' organization of water management in the Office du Niger irrigation scheme in Mali by Vandersypen, K, Keita, A.C.T, Kaloga, K, Coulibaly, Y, Raes, D, Jamin, J.Y

“…The Office du Niger is a centrally managed collective irrigation scheme of 80 000 ha, mainly cultivated with flooded rice. In the context of recent reforms,…”
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Participation in a Complex and Conflicting Context: Implementing a Shared Diagnosis in a Northern Tunisia Irrigation Scheme by Hanafi, S., Marlet, S., Jamin, J.Y., Imache, A., Zairi, A., Bahri, H., Rougier, J.E., Bouarfa, S.

“…Promoting innovation to improve both productivity and sustainability of irrigated farming systems is crucial for the first question addressed within the…”
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Clinical and pre-clinical biomarkers of Regorafenib (REG) efficacy in metastatic colorectal cancer (mCRC) in a phase II trial by Khan, K., Cunningham, D., Vlachogiannis, G., Hedayat, S., Rata, M., Koh, D-M., Tunariu, N., Jamin, Y., Collins, D., Chau, I., Rao, S., Watkins, D., Starling, N., Peckitt, C., Fotiadis, N., Saffery, C., Hahne, J., Fassan, M., Braconi, C., Valeri, N.

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Abstract B12: The ALK inhibitor PF-06463922 shows significant response as a single agent in ALK/MYCN driven models of neuroblastoma by Guan, J., Danielson, L., Chand, D., Jamin, Y., Ruuth, K., Tucker, E., Umapathy, G., Wakil, A. El, Witek, B., Johnson, T. W., Smeal, T., Chesler, L., Palmer, R. H., Hallberg, B.

“…Abstract ALK inhibitors such as the ALK/MET/ROS1 inhibitor crizotinib (Xalkori) have shown clinical efficacy in a number of tumour types. However, in ALK…”
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Irrigation performance at tertiary level in the rice schemes of the Office du Niger (Mali): Adequate water delivery through over-supply by Vandersypen, Klaartje, Bengaly, Kongotigui, Keita, Abdoulaye C.T., Sidibe, Souleymane, Raes, Dirk, Jamin, Jean-Yves

“…The performance of irrigation in rice schemes of the Office du Niger in 1995 is compared with the situation nearly 10 years later (2004). Major physical…”
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