Search Results - "Jamin, Emilien L"

Multi‐omics approach to understand the impact of sun exposure on an in vitro skin ecosystem and evaluate a new broad‐spectrum sunscreen by Jacques, Carine, Bacqueville, Daniel, Jamin, Emilien L., Maitre, Martine, Delsol, Cécile, Simcic‐Mori, Aimée, Bianchi, Pascale, Noustens, Anais, Jouanin, Isabelle, Debrauwer, Laurent, Bessou‐Touya, Sandrine, Stockfleth, Eggert, Duplan, Hélène

“…A reconstructed human epidermal model (RHE) colonized with human microbiota and sebum was developed to reproduce the complexity of the skin ecosystem in vitro…”
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Combination of Isotope Labeling and Molecular Networking of Tandem Mass Spectrometry Data To Reveal 69 Unknown Metabolites Produced by Penicillium nordicum by Hautbergue, Thaïs, Jamin, Emilien L, Costantino, Robin, Tadrist, Souria, Meneghetti, Lauriane, Tabet, Jean-Claude, Debrauwer, Laurent, Oswald, Isabelle P, Puel, Olivier

“…The secondary metabolome of Penicillium nordicum is poorly documented despite its frequent detection on contaminated food and its capacity to produce toxic…”
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Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis by Jamin, Emilien L, Riu, Anne, Douki, Thierry, Debrauwer, Laurent, Cravedi, Jean-Pierre, Zalko, Daniel, Audebert, Marc

“…Colorectal neoplasia is the third most common cancer worldwide. Environmental factors such as diet are known to be involved in the etiology of this cancer…”
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Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment by Tkalec, Žiga, Antignac, Jean-Philippe, Bandow, Nicole, Béen, Frederic M., Belova, Lidia, Bessems, Jos, Le Bizec, Bruno, Brack, Werner, Cano-Sancho, German, Chaker, Jade, Covaci, Adrian, Creusot, Nicolas, David, Arthur, Debrauwer, Laurent, Dervilly, Gaud, Duca, Radu Corneliu, Fessard, Valérie, Grimalt, Joan O., Guerin, Thierry, Habchi, Baninia, Hecht, Helge, Hollender, Juliane, Jamin, Emilien L., Klánová, Jana, Kosjek, Tina, Krauss, Martin, Lamoree, Marja, Lavison-Bompard, Gwenaelle, Meijer, Jeroen, Moeller, Ruth, Mol, Hans, Mompelat, Sophie, Van Nieuwenhuyse, An, Oberacher, Herbert, Parinet, Julien, Van Poucke, Christof, Roškar, Robert, Togola, Anne, Trontelj, Jurij, Price, Elliott J.

“…•Outlines ways to overcome the barriers for innovative methodologies in chemical risk assessment.•Barriers include chemical detection, annotation,…”
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Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice by Smith, Lorraine, Klément, Wendy, Dopavogui, Léonie, de Bock, Frédéric, Lasserre, Frédéric, Barretto, Sharon, Lukowicz, Céline, Fougerat, Anne, Polizzi, Arnaud, Schaal, Benoist, Patris, Bruno, Denis, Colette, Feuillet, Guylène, Canlet, Cécile, Jamin, Emilien L, Debrauwer, Laurent, Mselli-Lakhal, Laila, Loiseau, Nicolas, Guillou, Hervé, Marchi, Nicola, Ellero-Simatos, Sandrine, Gamet-Payrastre, Laurence

“…We recently demonstrated that chronic dietary exposure to a mixture of pesticides at low-doses induced sexually dimorphic obesogenic and diabetogenic effects…”
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Untargeted profiling of pesticide metabolites by LC–HRMS: an exposomics tool for human exposure evaluation by Jamin, Emilien L., Bonvallot, Nathalie, Tremblay-Franco, Marie, Cravedi, Jean-Pierre, Chevrier, Cécile, Cordier, Sylvaine, Debrauwer, Laurent

“…Human exposure to xenobiotics is usually estimated by indirect methods. Biological monitoring has emerged during the last decade to improve assessment of…”
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Osmolality-based normalization enhances statistical discrimination of untargeted metabolomic urine analysis: results from a comparative study by Mervant, Loïc, Tremblay-Franco, Marie, Jamin, Emilien L., Kesse-Guyot, Emmanuelle, Galan, Pilar, Martin, Jean-François, Guéraud, Françoise, Debrauwer, Laurent

“…Introduction Because of its ease of collection, urine is one of the most commonly used matrices for metabolomics studies. However, unlike other biofluids,…”
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The Solvent Dimethyl Sulfoxide Affects Physiology, Transcriptome and Secondary Metabolism of Aspergillus flavus by Costes, Laura H, Lippi, Yannick, Naylies, Claire, Jamin, Emilien L, Genthon, Clémence, Bailly, Sylviane, Oswald, Isabelle P, Bailly, Jean-Denis, Puel, Olivier

“…Dimethyl sulfoxide (DSMO) is a simple molecule widely used because of its great solvating ability, but this solvent also has little-known biological effects,…”
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Miniaturized Two-Dimensional Heart Cutting for LC–MS-Based Metabolomics by Orlandi, Carla, Jacques, Carine, Duplan, Hélène, Debrauwer, Laurent, Jamin, Emilien L.

“…Liquid chromatography–mass spectrometry (LC–MS)-based metabolomics usually combines hydrophilic interaction liquid chromatography (HILIC) and reversed-phase…”
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Spatial metabolomics using mass-spectrometry imaging to decipher the impact of high red meat diet on the colon metabolome in rat by Ferey, Justine, Mervant, Loïc, Naud, Nathalie, Jamin, Emilien L., Pierre, Fabrice, Debrauwer, Laurent, Guéraud, Françoise

“…Colorectal cancer (CRC) is the third most common cancer in the world with a higher prevalence in the developed countries, mainly caused by environmental and…”
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Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor by Lukowicz, Céline, Ellero-Simatos, Sandrine, Régnier, Marion, Polizzi, Arnaud, Lasserre, Frédéric, Montagner, Alexandra, Lippi, Yannick, Jamin, Emilien L, Martin, Jean-François, Naylies, Claire, Canlet, Cécile, Debrauwer, Laurent, Bertrand-Michel, Justine, Al Saati, Talal, Théodorou, Vassilia, Loiseau, Nicolas, Mselli-Lakhal, Laïla, Guillou, Hervé, Gamet-Payrastre, Laurence

“…Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have…”
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FragHub: A Mass Spectral Library Data Integration Workflow by Dablanc, Axel, Hennechart, Solweig, Perez, Amélie, Cabanac, Guillaume, Guitton, Yann, Paulhe, Nils, Lyan, Bernard, Jamin, Emilien L., Giacomoni, Franck, Marti, Guillaume

“…Open mass spectral libraries (OMSLs) are critical for metabolite annotation and machine learning, especially given the rising volume of untargeted metabolomic…”
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Multi-omics analysis to evaluate the effects of solar exposure and a broad-spectrum SPF50+ sunscreen on markers of skin barrier function in a skin ecosystem model by Jacques, Carine, Jamin, Emilien L, Noustens, Anais, Lauze, Christophe, Jouanin, Isabelle, Doat, Gautier, Debrauwer, Laurent, Bessou-Touya, Sandrine, Stockfleth, Eggert, Duplan, Hélène

“…Sun exposure induces major skin alterations, but its effects on skin metabolites and lipids remain largely unknown. Using an original reconstructed human…”
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Metabolism of versicolorin A, a genotoxic precursor of aflatoxin B1: Characterization of metabolites using in vitro production of standards by Al-Ayoubi, Carine, Oules, Justin, Person, Elodie, Bruel, Sandrine, Bouville, Alyssa, Pinton, Philippe, Oswald, Isabelle P., Jamin, Emilien L., Puel, Olivier, Soler, Laura

“…The toxicity of mycotoxins containing bisfuranoid structures such as aflatoxin B1 (AFB1) depends largely on biotransformation processes. While the genotoxicity…”
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The fate of bisphenol A, bisphenol S, and their respective glucuronide metabolites in ovarian cells by Person, Elodie, Bruel, Sandrine, Manzano, Trishabelle I., Jamin, Emilien L., Zalko, Daniel, Combelles, Catherine MH

“…Ovarian cells are critical for reproduction and steroidogenesis, which are functions that can be impacted by exposure to xenobiotics. As in other extra-hepatic…”
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Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes by Liamin, Marie, Boutet-Robinet, Elisa, Jamin, Emilien L., Fernier, Morgane, Khoury, Laure, Kopp, Benjamin, Le Ferrec, Eric, Vignard, Julien, Audebert, Marc, Sparfel, Lydie

“…[Display omitted] Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (B[a]P), are widely distributed environmental contaminants exerting toxic…”
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A European proposal for quality control and quality assurance of tandem mass spectral libraries by Oberacher, Herbert, Sasse, Michael, Antignac, Jean-Philippe, Guitton, Yann, Debrauwer, Laurent, Jamin, Emilien L., Schulze, Tobias, Krauss, Martin, Covaci, Adrian, Caballero-Casero, Noelia, Rousseau, Kathleen, Damont, Annelaure, Fenaille, François, Lamoree, Marja, Schymanski, Emma L.

“…Background High resolution mass spectrometry (HRMS) is being used increasingly in the context of suspect and non-targeted screening for the identification of…”
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Global Profiling of Toxicologically Relevant Metabolites in Urine: Case Study of Reactive Aldehydes by Jamin, Emilien L, Costantino, Robin, Mervant, Loïc, Martin, Jean-François, Jouanin, Isabelle, Blas-Y-Estrada, Florence, Guéraud, Françoise, Debrauwer, Laurent

“…Among the numerous unknown metabolites representative of our exposure, focusing on toxic compounds should provide more relevant data to link exposure and…”
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Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles by Bacqueville, Daniel, Jacques, Carine, Duprat, Laure, Jamin, Emilien L., Guiraud, Beatrice, Perdu, Elisabeth, Bessou-Touya, Sandrine, Zalko, Daniel, Duplan, Hélène

“…In this study, a comprehensive characterization of xenobiotic metabolizing enzymes (XMEs) based on gene expression and enzyme functionality was made in a…”
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Safety assessment of cosmetics by read across applied to metabolomics data of in vitro skin and liver models by Jacques, Carine, Jamin, Emilien L., Jouanin, Isabelle, Canlet, Cécile, Tremblay-Franco, Marie, Martin, Jean-François, Zalko, Daniel, Brunel, Yves, Bessou-Touya, Sandrine, Debrauwer, Laurent, Ferret, Pierre-Jacques, Duplan, Hélène

“…As a result of the cosmetics testing ban, safety evaluations of cosmetics ingredients must now be conducted using animal-free methods. A common approach is…”
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