Search Results - "Jamieson, Beth D."

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease by Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L

“…Epigenetic biomarkers of aging (the "epigenetic clock") have the potential to address puzzling findings surrounding mortality rates and incidence of…”
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LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response by Bensinger, Steven J., Bradley, Michelle N., Joseph, Sean B., Zelcer, Noam, Janssen, Edith M., Hausner, Mary Ann, Shih, Roger, Parks, John S., Edwards, Peter A., Jamieson, Beth D., Tontonoz, Peter

“…Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are incompletely understood. We…”
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Relationship among serum levels of IL-6, sIL-6R, s gp130 and CD126 on T-cell in HIV-1 infected and uninfected men participating in the Los Angeles Multi-Center AIDS Cohort Study by Aziz, Najib, Shih, Roger, Alexopoulos, Nicole, Jamieson, Beth D, Mimiaga, Matthew J, Martinez-Maza, Otoniel, Detels, Roger

“…Interleukin 6 (IL-6) activates cells through its unique heterodimeric signaling complex of IL-6 receptor (IL6R) subunit and interleukin 6 signal transducer…”
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Acceleration of age-associated methylation patterns in HIV-1-infected adults by Rickabaugh, Tammy M, Baxter, Ruth M, Sehl, Mary, Sinsheimer, Janet S, Hultin, Patricia M, Hultin, Lance E, Quach, Austin, Martínez-Maza, Otoniel, Horvath, Steve, Vilain, Eric, Jamieson, Beth D

“…Patients with treated HIV-1-infection experience earlier occurrence of aging-associated diseases, raising speculation that HIV-1-infection, or antiretroviral…”
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Effect of HIV-infection and cumulative viral load on age-related decline in grip strength by Schrack, Jennifer A, Jacobson, Lisa P, Althoff, Keri N, Erlandson, Kristine M, Jamieson, Beth D, Koletar, Susan L, Phair, John, Brown, Todd T, Margolick, Joseph B

“…OBJECTIVE:Grip strength predicts functional decline and death, and is regarded as a biomarker of biological aging. The primary objective of this manuscript was…”
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Increased Rate of Epigenetic Aging in Men Living With HIV Prior to Treatment by Sehl, Mary E, Breen, Elizabeth Crabb, Shih, Roger, Chen, Larry, Wang, Ruibin, Horvath, Steve, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Jamieson, Beth D

“…Epigenetic aging is accelerated in tissues of persons living with HIV (PLWH) and may underlie the early onset of age-related illnesses. This study examines the…”
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Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments by Dock, Jeffrey, Ramirez, Christina M, Hultin, Lance, Hausner, Mary Ann, Hultin, Patricia, Elliott, Julie, Yang, Otto O, Anton, Peter A, Jamieson, Beth D, Effros, Rita B

“…A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability…”
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Copy number variation of KIR genes influences HIV-1 control by Pelak, Kimberly, Need, Anna C, Fellay, Jacques, Shianna, Kevin V, Feng, Sheng, Urban, Thomas J, Ge, Dongliang, De Luca, Andrea, Martinez-Picado, Javier, Wolinsky, Steven M, Martinson, Jeremy J, Jamieson, Beth D, Bream, Jay H, Martin, Maureen P, Borrow, Persephone, Letvin, Norman L, McMichael, Andrew J, Haynes, Barton F, Telenti, Amalio, Carrington, Mary, Goldstein, David B, Alter, Galit

“…A genome-wide screen for large structural variants showed that a copy number variant (CNV) in the region encoding killer cell immunoglobulin-like receptors…”
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Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop by Gabuzda, Dana, Jamieson, Beth D, Collman, Ronald G, Lederman, Michael M, Burdo, Tricia H, Deeks, Steven G, Dittmer, Dirk P, Fox, Howard S, Funderburg, Nicholas T, Pahwa, Savita G, Pandrea, Ivona, Wilson, Cara C, Hunt, Peter W

“…People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also…”
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Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo by Mu, Wenli, Rezek, Valerie, Martin, Heather, Carrillo, Mayra A, Tomer, Shallu, Hamid, Philip, Lizarraga, Miguel A, Tibbe, Tristan D, Yang, Otto O, Jamieson, Beth D, Kitchen, Scott G, Zhen, Anjie

“…A hallmark of HIV-1 infection is chronic inflammation, even in patients treated with antiretroviral therapy (ART). Chronic inflammation drives HIV-1…”
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Emergence and Persistence of CXCR4-Tropic HIV-1 in a Population of Men from the Multicenter AIDS Cohort Study by Shepherd, James, Jacobson, Lisa P., Qiao, Wei, Jamieson, Beth D., Phair, John P., Piazza, Paolo, Quinn, Thomas C., Margolick, Joseph B.

“…We examined the emergence of CXCR4 (i.e., X4) tropism in 67 male human immunodeficiency virus type 1 (HIV-1) seroconverters from the Multicenter AIDS Cohort…”
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Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV by Sehl, Mary E, Breen, Elizabeth Crabb, Shih, Roger, Li, Fengxue, Zhang, Joshua, Langfelder, Peter, Horvath, Steve, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Jamieson, Beth D

“…Persons living with HIV (PLWH) experience the early onset of age-related illnesses, even in the setting of successful human immunodeficiency virus (HIV)…”
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Overexpression of microRNAs from the miR-17-92 paralog clusters in AIDS-related non-Hodgkin's lymphomas by Thapa, Dharma R, Li, Xinmin, Jamieson, Beth D, Martínez-Maza, Otoniel

“…Individuals infected by HIV are at an increased risk for developing non-Hodgkin's lymphomas (AIDS-NHL). In the highly active antiretroviral therapy (HAART)…”
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Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV by Zhang, Joshua, Sehl, Mary E, Shih, Roger, Breen, Elizabeth Crabb, Li, Fengxue, Lu, Ake T, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Horvath, Steve, Jamieson, Beth D

“…Highly active antiretroviral therapy (HAART) helps improve some measures of accelerated epigenetic aging in persons living with HIV (PLWH), but its overall…”
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The dual impact of HIV-1 infection and aging on naïve CD4 T-cells: additive and distinct patterns of impairment by Rickabaugh, Tammy M, Kilpatrick, Ryan D, Hultin, Lance E, Hultin, Patricia M, Hausner, Mary Ann, Sugar, Catherine A, Althoff, Keri N, Margolick, Joseph B, Rinaldo, Charles R, Detels, Roger, Phair, John, Effros, Rita B, Jamieson, Beth D

“…HIV-1-infected adults over the age of 50 years progress to AIDS more rapidly than adults in their twenties or thirties. In addition, HIV-1-infected individuals…”
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The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults by Sehl, Mary E, Rickabaugh, Tammy M, Shih, Roger, Martinez-Maza, Otoniel, Horvath, Steve, Ramirez, Christina M, Jamieson, Beth D

“…HIV-1 infection is associated with acceleration of age-related methylation patterns in peripheral blood and brain of infected individuals although the relative…”
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Value of a Quality Assessment Program in Optimizing Cryopreservation of Peripheral Blood Mononuclear Cells in a Multicenter Study by Aziz, Najib, Margolick, Joseph B, Detels, Roger, Rinaldo, Charles R, Phair, John, Jamieson, Beth D, Butch, Anthony W

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Differential blood and mucosal immune responses against an HIV-1 vaccine administered via inguinal or deltoid injection by Yang, Otto O, Ibarrondo, F Javier, Price, Charles, Hultin, Lance E, Elliott, Julie, Hultin, Patricia M, Shih, Roger, Hausner, Mary Ann, Ng, Hwee L, Hoffman, Jennifer, Jamieson, Beth D, Anton, Peter A

“…Mucosal immunity is central to sexual transmission and overall pathogenesis of HIV-1 infection, but the ability of vaccines to induce immune responses in…”
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Natural killer T cells in advanced melanoma patients treated with tremelimumab by Ibarrondo, F Javier, Yang, Otto O, Chodon, Thinle, Avramis, Earl, Lee, Yohan, Sazegar, Hooman, Jalil, Jason, Chmielowski, Bartosz, Koya, Richard C, Schmid, Ingrid, Gomez-Navarro, Jesus, Jamieson, Beth D, Ribas, Antoni, Comin-Anduix, Begoña

“…A significant barrier to effective immune clearance of cancer is loss of antitumor cytotoxic T cell activity. Antibodies to block pro-apoptotic/downmodulatory…”
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Predictive Value of Immunologic and Virologic Markers After Long or Short Duration of HIV-1 Infection by Giorgi, Janis V, Lyles, Robert H, Matud, Jose L, Yamashita, Traci E, Mellors, John W, Hultin, Lance E, Jamieson, Beth D, Margolick, Joseph B, Rinaldo, Charles R, Phair, John P, Detels, Roger

“…Laboratory markers that predict HIV-1 disease progression include plasma viral burden, CD4 T-cell count, and CD38 expression on CD8 T cells. To better…”
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