Search Results - "Jamieson, Beth"

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease by Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L

“…Epigenetic biomarkers of aging (the "epigenetic clock") have the potential to address puzzling findings surrounding mortality rates and incidence of…”
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Relationship among serum levels of IL-6, sIL-6R, s gp130 and CD126 on T-cell in HIV-1 infected and uninfected men participating in the Los Angeles Multi-Center AIDS Cohort Study by Aziz, Najib, Shih, Roger, Alexopoulos, Nicole, Jamieson, Beth D, Mimiaga, Matthew J, Martinez-Maza, Otoniel, Detels, Roger

“…Interleukin 6 (IL-6) activates cells through its unique heterodimeric signaling complex of IL-6 receptor (IL6R) subunit and interleukin 6 signal transducer…”
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Acceleration of age-associated methylation patterns in HIV-1-infected adults by Rickabaugh, Tammy M, Baxter, Ruth M, Sehl, Mary, Sinsheimer, Janet S, Hultin, Patricia M, Hultin, Lance E, Quach, Austin, Martínez-Maza, Otoniel, Horvath, Steve, Vilain, Eric, Jamieson, Beth D

“…Patients with treated HIV-1-infection experience earlier occurrence of aging-associated diseases, raising speculation that HIV-1-infection, or antiretroviral…”
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Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments by Dock, Jeffrey, Ramirez, Christina M, Hultin, Lance, Hausner, Mary Ann, Hultin, Patricia, Elliott, Julie, Yang, Otto O, Anton, Peter A, Jamieson, Beth D, Effros, Rita B

“…A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability…”
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LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response by Bensinger, Steven J., Bradley, Michelle N., Joseph, Sean B., Zelcer, Noam, Janssen, Edith M., Hausner, Mary Ann, Shih, Roger, Parks, John S., Edwards, Peter A., Jamieson, Beth D., Tontonoz, Peter

“…Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are incompletely understood. We…”
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Effect of HIV-infection and cumulative viral load on age-related decline in grip strength by Schrack, Jennifer A, Jacobson, Lisa P, Althoff, Keri N, Erlandson, Kristine M, Jamieson, Beth D, Koletar, Susan L, Phair, John, Brown, Todd T, Margolick, Joseph B

“…OBJECTIVE:Grip strength predicts functional decline and death, and is regarded as a biomarker of biological aging. The primary objective of this manuscript was…”
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Copy number variation of KIR genes influences HIV-1 control by Pelak, Kimberly, Need, Anna C, Fellay, Jacques, Shianna, Kevin V, Feng, Sheng, Urban, Thomas J, Ge, Dongliang, De Luca, Andrea, Martinez-Picado, Javier, Wolinsky, Steven M, Martinson, Jeremy J, Jamieson, Beth D, Bream, Jay H, Martin, Maureen P, Borrow, Persephone, Letvin, Norman L, McMichael, Andrew J, Haynes, Barton F, Telenti, Amalio, Carrington, Mary, Goldstein, David B, Alter, Galit

“…A genome-wide screen for large structural variants showed that a copy number variant (CNV) in the region encoding killer cell immunoglobulin-like receptors…”
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Increased Rate of Epigenetic Aging in Men Living With HIV Prior to Treatment by Sehl, Mary E, Breen, Elizabeth Crabb, Shih, Roger, Chen, Larry, Wang, Ruibin, Horvath, Steve, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Jamieson, Beth D

“…Epigenetic aging is accelerated in tissues of persons living with HIV (PLWH) and may underlie the early onset of age-related illnesses. This study examines the…”
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Relationship Between a Frailty-Related Phenotype and Progressive Deterioration of the Immune System in HIV-Infected Men by Desquilbet, Loic, Margolick, Joseph B, Fried, Linda P, Phair, John P, Jamieson, Beth D, Holloway, Marcy, Jacobson, Lisa P

“…CONTEXT:Immunological similarities have been noted between HIV-infected individuals and older HIV-negative adults. Immunologic alterations with aging have been…”
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Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D by Schmid, Ingrid, Uittenbogaart, Christel, Jamieson, Beth D

“…This protocol describes a rapid and simple method for the identification of apoptotic cells. Owing to changes in membrane permeability, early apoptotic cells…”
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CD31, a Valuable Marker to Identify Early and Late Stages of T Cell Differentiation in the Human Thymus by Douaisi, Marc, Resop, Rachel S, Nagasawa, Maho, Craft, Joshua, Jamieson, Beth D, Blom, Bianca, Uittenbogaart, Christel H

“…Although CD31 expression on human thymocytes has been reported, a detailed analysis of CD31 expression at various stages of T cell development in the human…”
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HIV-1 Infection Is Associated With an Earlier Occurrence of a Phenotype Related to Frailty by Desquilbet, Loic, Jacobson, Lisa P., Fried, Linda P., Phair, John P., Jamieson, Beth D., Holloway, Marcy, Margolick, Joseph B.

“…Background. Older healthy and HIV-infected adults exhibit physiological similarities. Frailty is a clinical syndrome associated with aging that identifies a…”
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Longitudinal Intra- and Inter-individual variation in T-cell subsets of HIV-infected and uninfected men participating in the LA Multi-Center AIDS Cohort Study by Aziz, Najib, Jamieson, Beth D., Quint, Joshua J., Martinez-Maza, Otoniel, Chow, Marianne, Detels, Roger

“…To assess the intra-individual and inter-individuals biological variation and the effect of aging on lymphocyte T-cells subsets.We assessed lymphocyte…”
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Homeostasis of the Naive CD4+ T Cell Compartment during Aging by Kilpatrick, Ryan D, Rickabaugh, Tammy, Hultin, Lance E, Hultin, Patricia, Hausner, Mary Ann, Detels, Roger, Phair, John, Jamieson, Beth D

“…Despite thymic involution, the number of naive CD4(+) T cells diminishes slowly during aging, suggesting considerable peripheral homeostatic expansion of these…”
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The combined effects of age and HIV on the anatomic distribution of cortical and cancellous bone in the femoral neck among men and women by Abraham, Alison G., Sun, Jing, Sharma, Anjali, Yin, Michael T., Brown, J. Keenan, Demehri, Shadpour, Garza, Joshua, Shah, Jayesh G., Palella, Frank J., Kingsley, Lawrence, Jamieson, Beth D., Althoff, Keri N., Brown, Todd T.

“…To investigate HIV-related and age-related differences in hip bone structure in men and women. Cross sectional study of bone structure and HIV serostatus. We…”
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Overexpression of microRNAs from the miR-17-92 paralog clusters in AIDS-related non-Hodgkin's lymphomas by Thapa, Dharma R, Li, Xinmin, Jamieson, Beth D, Martínez-Maza, Otoniel

“…Individuals infected by HIV are at an increased risk for developing non-Hodgkin's lymphomas (AIDS-NHL). In the highly active antiretroviral therapy (HAART)…”
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The dual impact of HIV-1 infection and aging on naïve CD4 T-cells: additive and distinct patterns of impairment by Rickabaugh, Tammy M, Kilpatrick, Ryan D, Hultin, Lance E, Hultin, Patricia M, Hausner, Mary Ann, Sugar, Catherine A, Althoff, Keri N, Margolick, Joseph B, Rinaldo, Charles R, Detels, Roger, Phair, John, Effros, Rita B, Jamieson, Beth D

“…HIV-1-infected adults over the age of 50 years progress to AIDS more rapidly than adults in their twenties or thirties. In addition, HIV-1-infected individuals…”
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Accelerated Longitudinal Gait Speed Decline in HIV-Infected Older Men by Schrack, Jennifer A, Althoff, Keri N, Jacobson, Lisa P, Erlandson, Kristine M, Jamieson, Beth D, Koletar, Susan L, Phair, John, Ferrucci, Luigi, Brown, Todd T, Margolick, Joseph B

“…BACKGROUND:Gait speed predicts functional decline, disability, and death and is considered a biomarker of biological aging. Changes in gait speed in persons…”
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Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop by Gabuzda, Dana, Jamieson, Beth D, Collman, Ronald G, Lederman, Michael M, Burdo, Tricia H, Deeks, Steven G, Dittmer, Dirk P, Fox, Howard S, Funderburg, Nicholas T, Pahwa, Savita G, Pandrea, Ivona, Wilson, Cara C, Hunt, Peter W

“…People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also…”
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A frailty-related phenotype before HAART initiation as an independent risk factor for AIDS or death after HAART among HIV-infected men by Desquilbet, Loic, Jacobson, Lisa P, Fried, Linda P, Phair, John P, Jamieson, Beth D, Holloway, Marcy, Margolick, Joseph B

“…In the general population, frailty, a late stage of the aging process, predicts mortality. We investigated whether manifesting a previously defined…”
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