Search Results - "Jamey D. Marth"

Glycosylation in Cellular Mechanisms of Health and Disease by Ohtsubo, Kazuaki, Marth, Jamey D.

“…Glycosylation produces an abundant, diverse, and highly regulated repertoire of cellular glycans that are frequently attached to proteins and lipids. The past…”
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A unified vision of the building blocks of life by Marth, Jamey D

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Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport by Ohtsubo, Kazuaki, Chen, Mark Z, Olefsky, Jerrold M, Marth, Jamey D

“…Many mechanisms contribute to type 2 diabetes, but few connections have established a pathway from diet to disease. Jamey Marth and his colleagues now provide…”
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Recurrent infection progressively disables host protection against intestinal inflammation by Yang, Won Ho, Heithoff, Douglas M., Aziz, Peter V., Sperandio, Markus, Nizet, Victor, Mahan, Michael J., Marth, Jamey D.

“…Intestinal inflammation is the central pathological feature of colitis and the inflammatory bowel diseases. These syndromes arise from unidentified…”
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Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells by Li, Yun, Fu, Jianxin, Ling, Yun, Yago, Tadayuki, McDaniel, J. Michael, Song, Jianhua, Bai, Xia, Kondo, Yuji, Qin, Yannan, Hoover, Christopher, McGee, Samuel, Shao, Bojing, Liu, Zhenghui, Sonon, Roberto, Azadi, Parastoo, Marth, Jamey D., McEver, Rodger P., Ruan, Changgeng, Xia, Lijun

“…Most platelet membrane proteins are modified by mucin-type core 1-derived glycans (O-glycans). However, the biological importance of O-glycans in platelet…”
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Mammalian N-Glycan Branching Protects against Innate Immune Self-Recognition and Inflammation in Autoimmune Disease Pathogenesis by Green, Ryan S., Stone, Erica L., Tenno, Mari, Lehtonen, Eero, Farquhar, Marilyn G., Marth, Jamey D.

“…Autoimmune diseases are prevalent and often life-threatening syndromes, yet the pathogenic triggers and mechanisms involved remain mostly unresolved. Protein…”
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An intrinsic mechanism of secreted protein aging and turnover by Yang, Won Ho, Aziz, Peter V., Heithoff, Douglas M., Mahan, Michael J., Smith, Jeffrey W., Marth, Jamey D.

“…The composition and functions of the secreted proteome are controlled by the life spans of different proteins. However, unlike intracellular protein fate,…”
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Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning by Yang, Won Ho, Westman, Julia S., Heithoff, Douglas M., Sperandio, Markus, Cho, Jin Won, Mahan, Michael J., Marth, Jamey D.

“…Intestinal inflammation is the underlying basis of colitis and the inflammatory bowel diseases. These syndromes originate from genetic and environmental…”
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Quantitative selection and parallel characterization of aptamers by Cho, Minseon, Oh, Seung Soo, Nie, Jeff, Stewart, Ron, Eisenstein, Michael, Chambers, James, Marth, Jamey D., Walker, Faye, Thomson, James A., Soh, H. Tom

“…Aptamers are promising affinity reagents that are potentially well suited for high-throughput discovery, as they are chemically synthesized and discovered via…”
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The Ashwell receptor mitigates the lethal coagulopathy of sepsis by Le, Dzung T, Marth, Jamey D, Nizet, Victor, Uchiyama, Satoshi, Ditto, David, Grewal, Prabhjit K, Varki, Nissi

“…The Ashwell receptor, the major lectin of hepatocytes, rapidly clears from blood circulation glycoproteins bearing glycan ligands that include galactose and N…”
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Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing by Ersoy, Selvi C., Heithoff, Douglas M., Barnes, Lucien, Tripp, Geneva K., House, John K., Marth, Jamey D., Smith, Jeffrey W., Mahan, Michael J.

“…The emergence and prevalence of antibiotic-resistant bacteria are an increasing cause of death worldwide, resulting in a global ‘call to action’ to avoid…”
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Dual roles for hepatic lectin receptors in the clearance of chilled platelets by Hoffmeister, Karin M, Marth, Jamey D, Hartwig, John H, Josefsson, Emma C, Wandall, Hans H, Rumjantseva, Viktoria, Larson, Göran, Grewal, Prabhjit K, Sørensen, Anne Louise

“…Unlike other types of blood components, refrigeration of platelets leads to their rapid clearance from the circulation after transfusion. Platelets must…”
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Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands by Yang, Won Ho, Nussbaum, Claudia, Grewal, Prabhjit K., Marth, Jamey D., Sperandio, Markus

“…Binding of selectins to their glycan ligands is a prerequisite for successful leukocyte trafficking. During synthesis and transport through the secretory…”
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Dietary and Genetic Control of Glucose Transporter 2 Glycosylation Promotes Insulin Secretion in Suppressing Diabetes by Ohtsubo, Kazuaki, Takamatsu, Shinji, Minowa, Mari T., Yoshida, Aruto, Takeuchi, Makoto, Marth, Jamey D.

“…Pancreatic β cell-surface expression of glucose transporter 2 (Glut-2) is essential for glucose-stimulated insulin secretion, thereby controlling blood glucose…”
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Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor by Grewal, Prabhjit K., Aziz, Peter V., Uchiyama, Satoshi, Rubio, Gabriel R., Lardone, Ricardo D., Le, Dzung, Varki, Nissi M., Nizet, Victor, Marth, Jamey D.

“…The endocytic Ashwell-Morell receptor (AMR) of hepatocytes detects pathogen remodeling of host glycoproteins by neuraminidase in the bloodstream and mitigates…”
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A GENETIC APPROACH TO MAMMALIAN GLYCAN FUNCTION by Lowe, John B, Marth, Jamey D

“…The four essential building blocks of cells are proteins, nucleic acids, lipids, and glycans. Also referred to as carbohydrates, glycans are composed of…”
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Symbol nomenclature for glycan representation by Varki, Ajit, Cummings, Richard D, Esko, Jeffrey D, Freeze, Hudson H, Stanley, Pamela, Marth, Jamey D, Bertozzi, Carolyn R, Hart, Gerald W, Etzler, Marilynn E

“…The glycan symbol nomenclature proposed by Harvey et al. in these pages has relative advantages and disadvantages. The use of symbols to depict glycans…”
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MKK7 deficiency in mature neurons impairs parental behavior in mice by Shin, Tadashi, Hiraoka, Yuichi, Yamasaki, Tokiwa, Marth, Jamey D., Penninger, Josef M., Kanai‐Azuma, Masami, Tanaka, Kohichi, Kofuji, Satoshi, Nishina, Hiroshi

“…c‐Jun N‐terminal kinases (JNKs) are constitutively activated in mammalian brains and are indispensable for their development and neural functions. MKK7 is an…”
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Ogt-Dependent X-Chromosome-Linked Protein Glycosylation Is a Requisite Modification in Somatic Cell Function and Embryo Viability by O'Donnell, Niall, Zachara, Natasha E., Hart, Gerald W., Marth, Jamey D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Biosynthesis of the major brain gangliosides GD1a and GT1b by Sturgill, Elizabeth R, Aoki, Kazuhiro, Lopez, Pablo H H, Colacurcio, Daniel, Vajn, Katarina, Lorenzini, Ileana, Majić, Senka, Yang, Won Ho, Heffer, Marija, Tiemeyer, Michael, Marth, Jamey D, Schnaar, Ronald L

“…Gangliosides-sialylated glycosphingolipids-are the major glycoconjugates of nerve cells. The same four structures-GM1, GD1a, GD1b and GT1b-comprise the great…”
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