Search Results - "Jameson, Brian J."

A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2 by Jameson, 2nd, J Brian, Kantz, Auric, Schultz, Lena, Kalyanaraman, Chakrapani, Jacobson, Matthew P, Maloney, David J, Jadhav, Ajit, Simeonov, Anton, Holman, Theodore R

“…Lipoxygenase (LOX) enzymes catalyze the hydroperoxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with…”
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Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase by Deschamps, Joshua D, Ogunsola, Abiola F, Jameson, J. Brian, Yasgar, Adam, Flitter, Becca A, Freedman, Cody J, Melvin, Jeffrey A, Nguyen, Jason V. M. H, Maloney, David J, Jadhav, Ajit, Simeonov, Anton, Bomberger, Jennifer M, Holman, Theodore R

“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause nosocomial and chronic infections in immunocompromised patients. P. aeruginosa secretes a…”
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Analytical approaches for the evaluation of data deficient simulated leachable compounds in ENDS products: a case study by Smith, Cameron, Lyndon, Matthew, Jeong, Lena, Lehman, Danielle, Jameson, J Brian, Chevva, Harish, Ayala-Fierro, Felix, Cook, David, Carter, Karen, Oldham, Michael, Gillman, I Gene

“…Leachable investigations are routinely undertaken across a range of sectors (e.g., pharmaceuticals, medical devices, etc.) to determine whether chemicals from…”
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Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15-Lipoxygenase-1 by Rai, Ganesha, Kenyon, Victor, Jadhav, Ajit, Schultz, Lena, Armstrong, Michelle, Jameson, J. Brian, Hoobler, Eric, Leister, William, Simeonov, Anton, Holman, Theodore R, Maloney, David J

“…There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in cellular biology. Human reticulocyte 15-lipoxygenase-1 (15-hLO-1),…”
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Corrigendum: Analytical approaches for the evaluation of data deficient simulated leachable compounds in ENDS products: a case study by Smith, Cameron, Lyndon, Matthew, Jeong, Lena, Lehman, Danielle, Jameson, J Brian, Chevva, Harish, Ayala-Fierro, Felix, Cook, David, Carter, Karen, Oldham, Michael, Gillman, I Gene

“…[This corrects the article DOI: 10.3389/fchem.2023.1212744.]…”
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Synthesis and Structure–Activity Relationship Studies of 4‑((2-Hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase by Luci, Diane K., Jameson, J. Brian, Yasgar, Adam, Diaz, Giovanni, Joshi, Netra, Kantz, Auric, Markham, Kate, Perry, Steve, Kuhn, Norine, Yeung, Jennifer, Kerns, Edward H., Schultz, Lena, Holinstat, Michael, Nadler, Jerry L., Taylor-Fishwick, David A., Jadhav, Ajit, Simeonov, Anton, Holman, Theodore R., Maloney, David J.

“…Human lipoxygenases (LOXs) are a family of iron-containing enzymes which catalyze the oxidation of polyunsaturated fatty acids to provide the corresponding…”
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Non-Targeted Chemical Characterization of JUUL Virginia Tobacco Flavored Aerosols Using Liquid and Gas Chromatography by Crosswhite, Mark R., Bailey, Patrick C., Jeong, Lena N., Lioubomirov, Anastasia, Yang, Clarissa, Ozvald, Adam, Jameson, J. Brian, Gillman, I. Gene

“…The chemical constituents of JUUL Virginia Tobacco pods with 3.0% and 5.0% nicotine by weight (VT3 and VT5) were characterized by non-targeted analyses, an…”
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Determination of chemical constituent yields in e-cigarette aerosol using partial and whole pod collections, a comparative analysis by Jameson, J. Brian, Wang, Jiaming, Bailey, Patrick C., Oldham, Michael J., Smith, Cameron R., Jeong, Lena N., Cook, David K., Bates, Austin L., Ullah, Sifat, Pennington, Alexander S. C., Gillman, I. Gene

“…Literature reports the chemical constituent yields of electronic nicotine delivery systems (ENDS) aerosol collected using a range of aerosol collection…”
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Non-Targeted Chemical Characterization of JUUL-Menthol-Flavored Aerosols Using Liquid and Gas Chromatography by Crosswhite, Mark R, Jeong, Lena N, Bailey, Patrick C, Jameson, J. Brian, Lioubomirov, Anastasia, Cook, David, Yang, Clarissa, Ozvald, Adam, Lyndon, Matthew, Gillman, I. Gene

“…The aerosol constituents generated from JUUL Menthol pods with 3.0% and 5.0% nicotine by weight (Me3 and Me5) are characterized by a non-targeted approach,…”
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A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors by Jameson, J. Brian, Kenyon, Victor, Holman, Theodore R.

“…Lipoxygenases (LOXs) regulate inflammation through the production of a variety of molecules whose specific downstream effects are not entirely understood due…”
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Discovery of Potent and Selective Inhibitors of Human Platelet-Type 12- Lipoxygenase by Kenyon, Victor, Rai, Ganesha, Jadhav, Ajit, Schultz, Lena, Armstrong, Michelle, Jameson, J. Brian, Perry, Steven, Joshi, Netra, Bougie, James M, Leister, William, Taylor-Fishwick, David A, Nadler, Jerry L, Holinstat, Michael, Simeonov, Anton, Maloney, David J, Holman, Theodore R

“…We report the discovery of novel small molecule inhibitors of platelet-type 12-human lipoxygenase, which display nanomolar activity against the purified…”
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The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton by Fanning, Alan S., Jameson, Brian J., Jesaitis, Lynne A., Anderson, James Melvin

“…The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). ZO-1 has been…”
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Discovery and characterization of potent and selective inhibitors to human epithelial 15‐lipoxygenase‐2 (582.5) by Jameson, J Brian, Kantz, Auric, Jadhav, Ajit, Simeonov, Anton, Maloney, David, Holman, Ted

“…Lipoxygenase (LOX) enzymes catalyzes the peroxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with varying…”
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Characterization and inhibition studies for 15-lipoxygenase enzymes by Jameson, J Brian

“…The research presented in this dissertation focuses on two distinct areas of 15-lipoxygenase biology: screening and identification of inhibitors toward human…”
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