Search Results - "Jameson, Brian"
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Glucose-Lowering Agents and the Risk of Hypoglycemia: a Real-world Study
Published in Journal of general internal medicine : JGIM (01-01-2023)“…Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1RA) are increasingly recommended in type 2…”
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A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2
Published in PloS one (11-08-2014)“…Lipoxygenase (LOX) enzymes catalyze the hydroperoxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with…”
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Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase
Published in Biochemistry (Easton) (14-06-2016)“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause nosocomial and chronic infections in immunocompromised patients. P. aeruginosa secretes a…”
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Analytical approaches for the evaluation of data deficient simulated leachable compounds in ENDS products: a case study
Published in Frontiers in chemistry (04-08-2023)“…Leachable investigations are routinely undertaken across a range of sectors (e.g., pharmaceuticals, medical devices, etc.) to determine whether chemicals from…”
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Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15-Lipoxygenase-1
Published in Journal of medicinal chemistry (28-10-2010)“…There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in cellular biology. Human reticulocyte 15-lipoxygenase-1 (15-hLO-1),…”
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Corrigendum: Analytical approaches for the evaluation of data deficient simulated leachable compounds in ENDS products: a case study
Published in Frontiers in chemistry (28-11-2023)“…[This corrects the article DOI: 10.3389/fchem.2023.1212744.]…”
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Non-Targeted Chemical Characterization of JUUL Virginia Tobacco Flavored Aerosols Using Liquid and Gas Chromatography
Published in Separations (01-09-2021)“…The chemical constituents of JUUL Virginia Tobacco pods with 3.0% and 5.0% nicotine by weight (VT3 and VT5) were characterized by non-targeted analyses, an…”
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Determination of chemical constituent yields in e-cigarette aerosol using partial and whole pod collections, a comparative analysis
Published in Frontiers in chemistry (07-09-2023)“…Literature reports the chemical constituent yields of electronic nicotine delivery systems (ENDS) aerosol collected using a range of aerosol collection…”
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Non-Targeted Chemical Characterization of JUUL-Menthol-Flavored Aerosols Using Liquid and Gas Chromatography
Published in Separations (01-11-2022)“…The aerosol constituents generated from JUUL Menthol pods with 3.0% and 5.0% nicotine by weight (Me3 and Me5) are characterized by a non-targeted approach,…”
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Synthesis and Structure–Activity Relationship Studies of 4‑((2-Hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase
Published in Journal of medicinal chemistry (23-01-2014)“…Human lipoxygenases (LOXs) are a family of iron-containing enzymes which catalyze the oxidation of polyunsaturated fatty acids to provide the corresponding…”
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A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors
Published in Analytical biochemistry (01-05-2015)“…Lipoxygenases (LOXs) regulate inflammation through the production of a variety of molecules whose specific downstream effects are not entirely understood due…”
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Expression of DC-SIGN by Dendritic Cells of Intestinal and Genital Mucosae in Humans and Rhesus Macaques
Published in Journal of Virology (01-02-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery of Potent and Selective Inhibitors of Human Platelet-Type 12- Lipoxygenase
Published in Journal of medicinal chemistry (11-08-2011)“…We report the discovery of novel small molecule inhibitors of platelet-type 12-human lipoxygenase, which display nanomolar activity against the purified…”
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Rotation‐Inversion Isomerization of Tertiary Carbamates: Potential Energy Surface Analysis of Multi‐Paths Isomerization Using Boltzmann Statistics
Published in Chemphyschem (03-01-2023)“…Potential energy surface (PES) analyses at the SMD[MP2/6–311++G(d,p)] level and higher‐level energies up to MP4(fc,SDTQ) are reported for the fluorinated…”
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Rotation‐Inversion Isomerization of Tertiary Carbamates: Potential Energy Surface Analysis of Multi‐Paths Isomerization Using Boltzmann Statistics
Published in Chemphyschem (03-01-2023)“…The front cover artwork is provided by Prof. Rainer Glaser's group at the Missouri University of Science and Technology. The image shows one of four potential…”
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Cover Feature: Rotation‐Inversion Isomerization of Tertiary Carbamates: Potential Energy Surface Analysis of Multi‐Paths Isomerization Using Boltzmann Statistics (ChemPhysChem 1/2023)
Published in Chemphyschem (03-01-2023)“…The Cover Feature shows one of four potential energy surfaces generated from our rotation‐inversion study of tertiary carbamates and highlights two of the…”
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The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton
Published in The Journal of biological chemistry (06-11-1998)“…The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). ZO-1 has been…”
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Nuclear Magnetic Resonance Study of CO2 Capture by Fluoroalkylamines: Ammonium Ion pK a Depression via Fluorine Modification and Thermochemistry of Carbamylation
Published in Journal of organic chemistry (18-08-2023)“…We are developing energy-efficient and reversible carbon capture and release (CCR) systems that mimic the Lys201 carbamylation reaction in the active site of…”
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Nuclear Magnetic Resonance Study of CO 2 Capture by Fluoroalkylamines: Ammonium Ion p K a Depression via Fluorine Modification and Thermochemistry of Carbamylation
Published in Journal of organic chemistry (18-08-2023)“…We are developing energy-efficient and reversible carbon capture and release (CCR) systems that mimic the Lys carbamylation reaction in the active site of…”
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