Search Results - "James M. Antonini"

Using liquid chromatography mass spectrometry (LC-MS) to assess the effect of age, high-fat diet, and rat strain on the liver metabolome by Boyce, Greg, Shoeb, Mohammad, Kodali, Vamsi, Meighan, Terence, Roberts, Jenny R, Erdely, Aaron, Kashon, Michael, Antonini, James M

“…The goal of this study was to use liquid chromatography mass spectrometry to assess metabolic changes of two different diets in three distinct rat strains…”
Get full text

Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel by Falcone, Lauryn M, Erdely, Aaron, Salmen, Rebecca, Keane, Michael, Battelli, Lori, Kodali, Vamsi, Bowers, Lauren, Stefaniak, Aleksandr B, Kashon, Michael L, Antonini, James M, Zeidler-Erdely, Patti C

“…In 2017, the International Agency for Research on Cancer classified welding fumes as "carcinogenic to humans" (Group 1). Both mild steel (MS) welding, where…”
Get full text

A comparison of cytotoxicity and oxidative stress from welding fumes generated with a new nickel-, copper-based consumable versus mild and stainless steel-based welding in RAW 264.7 mouse macrophages by Badding, Melissa A, Fix, Natalie R, Antonini, James M, Leonard, Stephen S

“…Welding processes that generate fumes containing toxic metals, such as hexavalent chromium (Cr(VI)), manganese (Mn), and nickel (Ni), have been implicated in…”
Get full text

Exposure to welding fumes and lower airway infection with Streptococcus pneumoniae by Suri, Reetika, PhD, Periselneris, Jimstan, MB BS, Lanone, Sophie, PhD, Zeidler-Erdely, Patti C., PhD, Melton, Geoffrey, BSc, Palmer, Keith T., MD, Andujar, Pascal, MD, Antonini, James M., PhD, Cohignac, Vanessa, MSc, Erdely, Aaron, PhD, Jose, Ricardo J., MB BS, Mudway, Ian, PhD, Brown, Jeremy, MD, Grigg, Jonathan, MD

“…Background Welders are at increased risk of pneumococcal pneumonia. The mechanism for this association is not known. The capacity of pneumococci to adhere to…”
Get full text

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats by Skovmand, Astrid, Erdely, Aaron, Antonini, James M, Nurkiewicz, Timothy R, Shoeb, Mohammad, Eye, Tracy, Kodali, Vamsi, Loeschner, Katrin, Vidmar, Janja, Agerholm, Jørgen S, Goericke-Pesch, Sandra, Vogel, Ulla, Hougaard, Karin S

“…Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which…”
Get full text

Skin as a Route of Exposure and Sensitization in Chronic Beryllium Disease by Tinkle, Sally S., Antonini, James M., Rich, Brenda A., Roberts, Jenny R., Salmen, Rebecca, DePree, Karyn, Adkins, Eric J.

“…Chronic beryllium disease is an occupational lung disease that begins as a cell-mediated immune response to beryllium. Although respiratory and engineering…”
Get full text

Comparison of stainless and mild steel welding fumes in generation of reactive oxygen species by Leonard, Stephen S, Chen, Bean T, Stone, Samuel G, Schwegler-Berry, Diane, Kenyon, Allison J, Frazer, David, Antonini, James M

“…Welding fumes consist of a wide range of complex metal oxide particles which can be deposited in all regions of the respiratory tract. The welding aerosol is…”
Get full text

Dopaminergic neurotoxicity following pulmonary exposure to manganese-containing welding fumes by Sriram, Krishnan, Lin, Gary X, Jefferson, Amy M, Roberts, Jenny R, Chapman, Rebecca S, Chen, Bean T, Soukup, Joleen M, Ghio, Andrew J, Antonini, James M

“…The potential for development of Parkinson's disease (PD)-like neurological dysfunction following occupational exposure to aerosolized welding fumes (WF) is an…”
Get full text

Development of a thermal spray coating aerosol generator and inhalation exposure system by Afshari, Aliakbar A., McKinney, Walter, Cumpston, Jared L., Leonard, Howard D., Cumpston, James B., Meighan, Terence G., Jackson, Mark, Friend, Sherri, Kodali, Vamsi, Lee, Eun Gyung, Antonini, James M.

“…[Display omitted] •An automated thermal spray coating generator and inhalation exposure system was designed and developed.•The system can generate a consistent…”
Get full text

Welder's Anthrax: A Review of an Occupational Disease by de Perio, Marie A, Hendricks, Katherine A, Dowell, Chad H, Bower, William A, Burton, Nancy C, Dawson, Patrick, Schrodt, Caroline A, Salzer, Johanna S, Marston, Chung K, Feldmann, Karl, Hoffmaster, Alex R, Antonini, James M

“…Since 1997, nine cases of severe pneumonia, caused by species within the group and with a presentation similar to that of inhalation anthrax, were reported in…”
Get full text

Effect of short-term stainless steel welding fume inhalation exposure on lung inflammation, injury, and defense responses in rats by Antonini, James M., Stone, Sam, Roberts, Jenny R., Chen, Bean, Schwegler-Berry, Diane, Afshari, Aliakbar A., Frazer, David G.

“…Many welders have experienced bronchitis, metal fume fever, lung function changes, and an increase in the incidence of lung infection. Questions remain…”
Get full text

Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver by Boyce, Greg R., Shoeb, Mohammad, Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., McKinney, Walter, Stone, Samuel, Powell, Matthew J., Roberts, Jenny R., Zeidler-Erdely, Patti C., Erdely, Aaron, Antonini, James M.

“…It is estimated that greater than 1 million workers are exposed to welding fume (WF) by inhalation daily. The potentially toxic metals found in WF are known to…”
Get full text

Epidemiologic Investigation of Two Welder's Anthrax Cases Caused by Bacillus Cereus Group Bacteria: Occupational Link Established by Environmental Detection by Dawson, Patrick, Salzer, Johanna S, Schrodt, Caroline A, Feldmann, Karl, Kolton, Cari B, Gee, Jay E, Marston, Chung K, Gulvik, Christopher A, Elrod, Mindy G, Villarma, Aaron, Traxler, Rita M, Negrón, María E, Hendricks, Kate A, Moulton-Meissner, Heather, Rose, Laura J, Byers, Paul, Taylor, Kathryn, Ware, Daphne, Balsamo, Gary A, Sokol, Theresa, Barrett, Bret, Payne, Erica, Zaheer, Saad, Jung, Ga On, Long, Stephen, Quijano, Ricardo, LeBouf, Lindsey, O'Sullivan, Briana, Swaney, Erin, Antonini, James M, de Perio, Marie A, Weiner, Zachary, Bower, William A, Hoffmaster, Alex R

“…group bacteria containing the anthrax toxin genes can cause fatal anthrax pneumonia in welders. Two welder's anthrax cases identified in 2020 were investigated…”
Get full text

Pulmonary effects of welding fumes: Review of worker and experimental animal studies by Antonini, James M., Lewis, Anthony B., Roberts, Jenny R., Whaley, David A.

“…Background Approximately one million workers worldwide perform welding as part of their work duties. Electric arc welding processes produce metal fumes and…”
Get full text

Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice by Zeidler-Erdely, Patti C, Kashon, Michael L, Li, Shengqiao, Antonini, James M

“…Debate exists as to whether welding fume is carcinogenic, but epidemiological evidence suggests that welders are an at risk population for the development of…”
Get full text

Performance evaluation of cytometric bead assays for the measurement of lung cytokines in two rodent models by Young, Shih-Houng, Antonini, James M., Roberts, Jenny R., Erdely, Aaron D., Zeidler-Erdely, Patti C.

“…There is a growing demand for a cost-effective, efficient, and high-throughput method for measuring cytokines. Currently, many studies are using flow…”
Get full text

Sequential Exposure to Carbon Nanotubes and Bacteria Enhances Pulmonary Inflammation and Infectivity by Shvedova, Anna A, Fabisiak, James P, Kisin, Elena R, Murray, Ashley R, Roberts, Jenny R, Tyurina, Yulia Y, Antonini, James M, Feng, Wei Hong, Kommineni, Choudari, Reynolds, Jeffrey, Barchowsky, Aaron, Castranova, Vince, Kagan, Valerian E

Get full text

Telomeres in toxicology: Occupational health by Shoeb, Mohammad, Meier, Helen C.S., Antonini, James M.

“…The ends of chromosomes shorten at each round of cell division, and this process is thought to be affected by occupational exposures. Occupational hazards may…”
Get full text

Aerosol characterization and pulmonary responses in rats after short-term inhalation of fumes generated during resistance spot welding of galvanized steel by Antonini, James M, Afshari, Aliakbar, Meighan, Terence G, McKinney, Walter, Jackson, Mark, Schwegler-Berry, Diane, Burns, Dru A, LeBouf, Ryan F, Chen, Bean T, Shoeb, Mohammad, Zeidler-Erdely, Patti C

“…Resistance spot welding is a common process to join metals in the automotive industry. Adhesives are often used as sealers to seams of metals that are joined…”
Get full text

Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume by Zeidler-Erdely, Patti C, Kashon, Michael L, Battelli, Lori A, Young, Shih-Houng, Erdely, Aaron, Roberts, Jenny R, Reynolds, Steven H, Antonini, James M

“…Welding fume has been categorized as "possibly carcinogenic" to humans. Our objectives were to characterize the lung response to carcinogenic and…”
Get full text