Search Results - "James, Sally"

Subtype-specific regulatory network rewiring in acute myeloid leukemia by Assi, Salam A., Imperato, Maria Rosaria, Coleman, Daniel J. L., Pickin, Anna, Potluri, Sandeep, Ptasinska, Anetta, Chin, Paulynn Suyin, Blair, Helen, Cauchy, Pierre, James, Sally R., Zacarias-Cabeza, Joaquin, Gilding, L. Niall, Beggs, Andrew, Clokie, Sam, Loke, Justin C., Jenkin, Phil, Uddin, Ash, Delwel, Ruud, Richards, Stephen J., Raghavan, Manoj, Griffiths, Michael J., Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze

“…Acute myeloid leukemia (AML) is a heterogeneous disease caused by a variety of alterations in transcription factors, epigenetic regulators and signaling…”
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Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal by Ptasinska, Anetta, Assi, Salam A., Martinez-Soria, Natalia, Imperato, Maria Rosaria, Piper, Jason, Cauchy, Pierre, Pickin, Anna, James, Sally R., Hoogenkamp, Maarten, Williamson, Dan, Wu, Mengchu, Tenen, Daniel G., Ott, Sascha, Westhead, David R., Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze

“…Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21), subvert normal blood cell development by…”
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Abnormal fibre usage in UC in remission by James, Sally L, Christophersen, Claus T, Bird, Anthony R, Conlon, Michael A, Rosella, Ourania, Gibson, Peter R, Muir, Jane G

“…Colonic fermentation in patients with UC in remission was compared with that in matched healthy subjects on habitual diets and when dietary fibre was…”
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Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature by Cauchy, Pierre, James, Sally R., Zacarias-Cabeza, Joaquin, Ptasinska, Anetta, Imperato, Maria Rosaria, Assi, Salam A., Piper, Jason, Canestraro, Martina, Hoogenkamp, Maarten, Raghavan, Manoj, Loke, Justin, Akiki, Susanna, Clokie, Samuel J., Richards, Stephen J., Westhead, David R., Griffiths, Michael J., Ott, Sascha, Bonifer, Constanze, Cockerill, Peter N.

“…Acute myeloid leukemia (AML) is characterized by recurrent mutations that affect the epigenetic regulatory machinery and signaling molecules, leading to a…”
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Microexon gene transcriptional profiles and evolution provide insights into blood processing by the Schistosoma japonicum esophagus by Li, Xiao-Hong, DeMarco, Ricardo, Neves, Leandro X, James, Sally R, Newling, Katherine, Ashton, Peter D, Cao, Jian-Ping, Wilson, R Alan, Castro-Borges, William

“…Adult schistosomes have a well-developed alimentary tract comprising an oral sucker around the mouth, a short esophagus and a blind ending gut. The esophagus…”
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Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis by Fraser, Simon D., Thackray-Nocera, Susannah, Wright, Caroline, Flockton, Rachel, James, Sally R., Crooks, Michael G., Kaye, Paul M., Hart, Simon P.

“…Introduction In sarcoidosis granulomas, monocyte-derived macrophages are activated by pro-inflammatory cytokines including TNF and IL-6. Current drug treatment…”
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Human cell dedifferentiation in mesenchymal condensates through controlled autophagy by Pennock, Rebecca, Bray, Elen, Pryor, Paul, James, Sally, McKeegan, Paul, Sturmey, Roger, Genever, Paul

“…Tissue and whole organ regeneration is a dramatic biological response to injury that occurs across different plant and animal phyla. It frequently requires the…”
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Pseudomolecule-scale genome assemblies of Drepanocaryum sewerzowii and Marmoritis complanata by Smit, Samuel J, Whitehead, Caragh, James, Sally R, Jeffares, Daniel C, Godden, Grant, Peng, Deli, Sun, Hang, Lichman, Benjamin R

“…Abstract The Nepetoideae, a subfamily of Lamiaceae (mint family), is rich in aromatic plants, many of which are sought after for their use as flavors and…”
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Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients by Pirmohamed, Munir, James, Sally, Meakin, Shaun, Green, Chris, Scott, Andrew K, Walley, Thomas J, Farrar, Keith, Park, B Kevin, Breckenridge, Alasdair M

“…Abstract Objective To ascertain the current burden of adverse drug reactions (ADRs) through a prospective analysis of all admissions to hospital. Design…”
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Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes by James, Sally, Fox, James, Afsari, Farinaz, Lee, Jennifer, Clough, Sally, Knight, Charlotte, Ashmore, James, Ashton, Peter, Preham, Olivier, Hoogduijn, Martin, Ponzoni, Raquel De Almeida Rocha, Hancock, Y., Coles, Mark, Genever, Paul

“…Bone marrow stromal cells (BMSCs, also called bone-marrow-derived mesenchymal stromal cells) provide hematopoietic support and immunoregulation and contain a…”
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CD317-Positive Immune Stromal Cells in Human "Mesenchymal Stem Cell" Populations by Kay, Alasdair G, Fox, James M, Hewitson, James P, Stone, Andrew P, Robertson, Sophie, James, Sally, Wang, Xiao-Nong, Kapasa, Elizabeth, Yang, Xuebin B, Genever, Paul G

“…Heterogeneity of bone marrow mesenchymal stromal cells (MSCs, frequently referred to as "mesenchymal stem cells") clouds biological understanding and hampers…”
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Whole genome structural predictions reveal hidden diversity in putative oxidative enzymes of the lignocellulose-degrading ascomycete Parascedosporium putredinis NO1 by Scott, Conor J R, Leadbeater, Daniel R, Oates, Nicola C, James, Sally R, Newling, Katherine, Li, Yi, McGregor, Nicholas G S, Bird, Susannah, Bruce, Neil C

“…An annotated reference genome has revealed NO1 as a useful resource for the identification of new lignocellulose-degrading enzymes for biorefining of woody…”
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Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19 by Wilson, Julie C., Kealy, David, James, Sally R., Plowman, Tobias, Newling, Katherine, Jagger, Christopher, Filbey, Kara, Mann, Elizabeth R., Konkel, Joanne E., Menon, Madhvi, Knight, Sean B., Simpson, Angela, Prihartadi, Aliya, Forshaw, Greg, Todd, Neil, Yates, David R.A., Grainger, John R., Hussell, Tracy, Kaye, Paul M., Signoret, Nathalie, Lagos, Dimitris

“…Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with similar circulating CC levels present with different disease severity…”
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Antigenic epitope targets of rhesus macaques self-curing from Schistosoma mansoni infection by Vance, Gillian M, Khouri, Mariana I, Neto, Almiro Pires da Silva, James, Sally, Leite, Luciana C C, Farias, Leonardo Paiva, Wilson, R Alan

“…The self-cure of rhesus macaques from a schistosome infection and their subsequent strong immunity to a cercarial challenge should provide novel insights into…”
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Cell Death in Pseudomonas aeruginosa Biofilm Development by Webb, Jeremy S, Thompson, Lyndal S, James, Sally, Charlton, Tim, Tolker-Nielsen, Tim, Koch, Birgit, Givskov, Michael, Kjelleberg, Staffan

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Corrigendum: CD317-Positive Immune Stromal Cells in Human "Mesenchymal Stem Cell" Populations by Kay, Alasdair G, Fox, James M, Hewitson, James P, Stone, Andrew P, Robertson, Sophie, James, Sally, Wang, Xiao-Nong, Kapasa, Elizabeth, Yang, Xuebin B, Genever, Paul G

“…[This corrects the article DOI: 10.3389/fimmu.2022.903796.]…”
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The Schistosome Esophagus Is a 'Hotspot' for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing by Wilson, R Alan, Li, Xiao Hong, MacDonald, Sandy, Neves, Leandro Xavier, Vitoriano-Souza, Juliana, Leite, Luciana C C, Farias, Leonardo P, James, Sally, Ashton, Peter D, DeMarco, Ricardo, Castro Borges, William

“…The schistosome esophagus is divided into anterior and posterior compartments, each surrounded by a dense cluster of gland cell bodies, the source of distinct…”
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Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei by Davey, John W, Catta-Preta, Carolina M C, James, Sally, Forrester, Sarah, Motta, Maria Cristina M, Ashton, Peter D, Mottram, Jeremy C

“…Angomonas deanei is an endosymbiont-bearing trypanosomatid with several highly fragmented genome assemblies and unknown chromosome number. We present an…”
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A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer by Smith, Vicki E, Read, Martin L, Turnell, Andrew S, Watkins, Rachel J, Watkinson, John C, Lewy, Greg D, Fong, Jim C W, James, Sally R, Eggo, Margaret C, Boelaert, Kristien, Franklyn, Jayne A, McCabe, Christopher J

“…Differentiated thyroid cancers and their metastases frequently exhibit reduced iodide uptake, impacting on the efficacy of radioiodine ablation therapy. PTTG…”
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Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192 by Boissinot, Marjorie, Inman, Martyn, Hempshall, Aiden, James, Sally R, Gill, Jason H, Selby, Peter, Bowen, David T, Grigg, Ronald, Cockerill, Peter N

“…Abstract Histone deacetylase inhibitors (HDACIs) are in advanced clinical development as cancer therapeutic agents. However, first generation HDACIs such as…”
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